Differential protein expression profiling of myocardial tissue in a mouse model of hypertrophic cardiomyopathy.

[1]  L. Wold,et al.  Cytoskeletal remodeling of desmin is a more accurate measure of cardiac dysfunction than fibrosis or myocyte hypertrophy. , 2008, Life sciences.

[2]  G. Cooper,et al.  Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats , 2008, Proteomics.

[3]  J. Seidman,et al.  Severe Heart Failure and Early Mortality in a Double-Mutation Mouse Model of Familial Hypertrophic Cardiomyopathy , 2008, Circulation.

[4]  Andrew Emili,et al.  Comparative Proteomics Profiling of a Phospholamban Mutant Mouse Model of Dilated Cardiomyopathy Reveals Progressive Intracellular Stress Responses*S , 2008, Molecular & Cellular Proteomics.

[5]  R. Solaro,et al.  Use of 2‐D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy , 2008, Proteomics.

[6]  J. Arthur,et al.  Proteome map of the normal murine ventricular myocardium , 2007, Proteomics.

[7]  K. Kawakami,et al.  A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. , 2007, The Journal of clinical investigation.

[8]  C. Semsarian,et al.  Abnormal cardiac response to exercise in a murine model of familial hypertrophic cardiomyopathy. , 2007, International journal of cardiology.

[9]  D. Allen,et al.  Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy. , 2006, Journal of molecular and cellular cardiology.

[10]  C. Semsarian,et al.  Application of proteomics in cardiovascular medicine. , 2006, International journal of cardiology.

[11]  Guoqiang Chen,et al.  Differential protein expression in hypertrophic heart with and without hypertension in spontaneously hypertensive rats , 2006, Proteomics.

[12]  Jun Kawai,et al.  LOCATE: a mouse protein subcellular localization database , 2005, Nucleic Acids Res..

[13]  M. J. Faber,et al.  Recent developments in proteomics , 2006, Cell Biochemistry and Biophysics.

[14]  S. Nagueh,et al.  Prevention of Cardiac Hypertrophy by Atorvastatin in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy , 2005, Circulation research.

[15]  M. J. Faber,et al.  Proteomic changes in the pressure overloaded right ventricle after 6 weeks in young rats: Correlations with the degree of hypertrophy , 2005, Proteomics.

[16]  Melanie Y. White,et al.  Proteomics of ischemia/reperfusion injury in rabbit myocardium reveals alterations to proteins of essential functional systems , 2005, Proteomics.

[17]  J. Rüegg,et al.  Increased calcium sensitivity of chemically skinned human atria by myosin light chain kinase , 1988, Basic Research in Cardiology.

[18]  J. Vockley,et al.  Proteomic analysis of hyperdynamic mouse hearts with enhanced sarcoplasmic reticulum calcium cycling , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  M. Campbell,et al.  PANTHER: a library of protein families and subfamilies indexed by function. , 2003, Genome research.

[20]  H. Watkins,et al.  Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion. , 2003, Trends in genetics : TIG.

[21]  G. Hasenfuss,et al.  The effect of myosin light chain 2 dephosphorylation on Ca2+ -sensitivity of force is enhanced in failing human hearts. , 2003, Cardiovascular research.

[22]  C. Semsarian,et al.  Hypertrophic cardiomyopathy: from gene defect to clinical disease , 2003, Cell Research.

[23]  J. Schmitt,et al.  The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model , 2002 .

[24]  J. Robbins,et al.  Phenotypic deficits in mice expressing a myosin binding protein C lacking the titin and myosin binding domains. , 2001, Journal of molecular and cellular cardiology.

[25]  F J Schoen,et al.  Comparison of Two Murine Models of Familial Hypertrophic Cardiomyopathy , 2001, Circulation research.

[26]  G. Cuda,et al.  Changes in myocardial cytoskeletal intermediate filaments and myocyte contractile dysfunction in dilated cardiomyopathy: an in vivo study in humans , 2000, Heart.

[27]  S. Kitazawa,et al.  Isoproterenol‐induced myocardial injury resulting in altered S100A4 and S100A11 protein expression in the rat , 2000, Pathology international.

[28]  W. Schaper,et al.  Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium. , 2000, Circulation research.

[29]  C. Heizmann,et al.  Right ventricular upregulation of the Ca(2+) binding protein S100A1 in chronic pulmonary hypertension. , 2000, Biochimica et biophysica acta.

[30]  P. Trouvé,et al.  Expression and Localization of the Annexins II, V, and VI in Myocardium from Patients with End-Stage Heart Failure , 2000, Laboratory Investigation.

[31]  G. Taffet,et al.  The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function. , 1999, Journal of molecular and cellular cardiology.

[32]  P. Trouvé,et al.  Localization and quantitation of cardiac annexins II, V, and VI in hypertensive guinea pigs. , 1999, American journal of physiology. Heart and circulatory physiology.

[33]  J. Yates,et al.  Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry. , 1998, Analytical biochemistry.

[34]  M. Yacoub,et al.  Cardiac protein abnormalities in dilated cardiomyopathy detected by two‐dimensional polyacrylamide gel electrophoresis , 1998, Electrophoresis.

[35]  D. Arnott,et al.  An integrated approach to proteome analysis: identification of proteins associated with cardiac hypertrophy. , 1998, Analytical biochemistry.

[36]  K P Fung,et al.  A genome-based resource for molecular cardiovascular medicine: toward a compendium of cardiovascular genes. , 1997, Circulation.

[37]  M. Matsuzaki,et al.  Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy , 1997, Nature Genetics.

[38]  C. Heizmann,et al.  Altered expression of the Ca(2+)-binding protein S100A1 in human cardiomyopathy. , 1996, Biochimica et biophysica acta.

[39]  F O Mueller,et al.  Sudden death in young competitive athletes. Clinical, demographic, and pathological profiles. , 1996, JAMA.

[40]  H. Sato,et al.  Cytoskeletal role in the contractile dysfunction of cardiocytes from hypertrophied and failing right ventricular myocardium. , 1996, Proceedings of the Association of American Physicians.

[41]  J. Gardin,et al.  Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults. , 1995, Circulation.