Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival
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Ashley R. Jones | G. Breen | A. Al-Chalabi | C. Shaw | J. Glass | O. Hardiman | J. Landers | R. McLaughlin | P. van Damme | L. H. van den Berg | J. Veldink | V. Drory | M. de Carvalho | K. Morrison | P. Vourc'h | P. Shaw | S. Pinto | P. Corcia | P. Couratier | Markus Weber | N. Ticozzi | V. Silani | P. Andersen | R. Dobson | M. Gotkine | J. Cooper-Knock | P. Van Damme | A. Iacoangeli | I. Fogh | M. Povedano | A. Al Khleifat | P. Andersen | P. Couratier | V. Silani | M. de Carvalho | J. M. Mora Pardina | S. Pinto | C. E. Shaw | O. Hardiman | M. Povedano Panadés | N. Başak | P. Corcia | M. Wéber | A. Jones | B. Adey | J. Glass | R. Dobson | P. Shaw | Richard Dobson
[1] Ewout J. N. Groen,et al. Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology , 2021, Nature Genetics.
[2] Ashley R. Jones,et al. SCFD1 expression quantitative trait loci in amyotrophic lateral sclerosis are differentially expressed , 2021, Brain communications.
[3] Ashley R. Jones,et al. A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex , 2021, Scientific Reports.
[4] Yan Li,et al. Caveolin-1, a novel player in cognitive decline , 2021, Neuroscience & Biobehavioral Reviews.
[5] H. Patel,et al. Subpial Gene Delivery of synapsin‐promoted Caveolin‐1 Prolongs Survival in hSODG93A mice Model of ALS , 2021, The FASEB Journal.
[6] M. Snyder,et al. Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis , 2020, Neuron.
[7] Andrea D Matlock,et al. Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines , 2020, Nature Neuroscience.
[8] L. Van Den Bosch,et al. C9orf72 loss-of-function: a trivial, stand-alone or additive mechanism in C9 ALS/FTD? , 2020, Acta Neuropathologica.
[9] M. Igarashi,et al. Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation , 2020, Frontiers in Molecular Neuroscience.
[10] N. Wray,et al. Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene , 2020, Cell reports.
[11] N. Wray,et al. ALS in Danish Registries , 2020, Neurology: Genetics.
[12] F. Mastaglia,et al. Structural Variants May Be a Source of Missing Heritability in sALS , 2020, Frontiers in Neuroscience.
[13] O. Hardiman,et al. Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis. , 2019, JAMA neurology.
[14] Xiao-fan Jiang,et al. Neurons can upregulate Cav-1 to increase intake of endothelial cells-derived extracellular vesicles that attenuate apoptosis via miR-1290 , 2019, Cell Death & Disease.
[15] S. Newhouse,et al. C9orf72 intermediate expansions of 24–30 repeats are associated with ALS , 2019, Acta Neuropathologica Communications.
[16] Alexander I. Young. Solving the missing heritability problem , 2019, PLoS genetics.
[17] H. Patel,et al. Neuron‐targeted caveolin‐1 improves neuromuscular function and extends survival in SOD1G93A mice , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[18] Timothy A. Miller,et al. Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia , 2019, bioRxiv.
[19] C. Mandyam,et al. Neuron-Targeted Caveolin-1 Promotes Ultrastructural and Functional Hippocampal Synaptic Plasticity , 2018, Cerebral cortex.
[20] E. Fraenkel,et al. Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism , 2018, eLife.
[21] J. Rowe,et al. Genetic screening in sporadic ALS and FTD , 2017, Journal of Neurology, Neurosurgery, and Psychiatry.
[22] Annelot M. Dekker,et al. Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis , 2017, European Journal of Human Genetics.
[23] C. Mandyam,et al. Neuron‐specific caveolin‐1 overexpression improves motor function and preserves memory in mice subjected to brain trauma , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[24] A. Al-Chalabi,et al. Gene discovery in amyotrophic lateral sclerosis: implications for clinical management , 2017, Nature Reviews Neurology.
[25] C. Mandyam,et al. Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice , 2017, Biological Psychiatry.
[26] T. Hortobágyi,et al. Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria , 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.
[27] Zhi-rui Zhou,et al. Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis , 2017, Journal of Neurology, Neurosurgery & Psychiatry.
[28] A. Al-Chalabi,et al. Amyotrophic lateral sclerosis: moving towards a new classification system , 2016, The Lancet Neurology.
[29] Annelot M. Dekker,et al. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis , 2016, Nature Genetics.
[30] J. Taipale,et al. The role of enhancers in cancer , 2016, Nature Reviews Cancer.
[31] Robert H. Brown,et al. Endogenous retroviruses in ALS: A reawakening? , 2015, Science Translational Medicine.
[32] Christian A. Ross,et al. Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS , 2015, Nature Neuroscience.
[33] B. Cupid,et al. Establishing the UK DNA Bank for motor neuron disease (MND) , 2015, BMC Genetics.
[34] P. Scacheri,et al. Enhancer variants: evaluating functions in common disease , 2014, Genome Medicine.
[35] A. Al-Chalabi,et al. The epidemiology of ALS: a conspiracy of genes, environment and time , 2013, Nature Reviews Neurology.
[36] P. Insel,et al. Neuron-targeted Caveolin-1 Protein Enhances Signaling and Promotes Arborization of Primary Neurons* , 2011, The Journal of Biological Chemistry.
[37] A. Miyanohara,et al. Loss of Caveolin-1 Accelerates Neurodegeneration and Aging , 2010, PloS one.
[38] A. Al-Chalabi,et al. An estimate of amyotrophic lateral sclerosis heritability using twin data , 2010, Journal of Neurology, Neurosurgery & Psychiatry.
[39] Orla Hardiman,et al. Cognitive impairment in amyotrophic lateral sclerosis , 2007, The Lancet Neurology.
[40] B. Miller,et al. Are amyotrophic lateral sclerosis patients cognitively normal? , 2003, Neurology.
[41] E. Suchman,et al. The American Soldier: Adjustment During Army Life. , 1949 .
[42] E. Suchman,et al. The American soldier: Adjustment during army life. (Studies in social psychology in World War II), Vol. 1 , 1949 .