Phase-detection-sensitivity enhancement of grating-coupled surface plasmon resonance sensor with light incident at nonzero azimuth angle

Abstract. We have numerically and experimentally demonstrated the enhancement of phase detection sensitivity of a grating-coupled surface plasmon resonance (GCSPR) sensor by using incident light at a nonzero azimuth angle. Phase detection measurements were performed using an electro-optic heterodyne interferometer. When the GCSPR sensor was rotated azimuthally by 0 deg and 58 deg, the phase detection sensitivities were approximately 3.2×10−7  RIU and 5.5×10−8  RIU, respectively. The azimuth angle of 58 deg was found to enhance the sensor sensitivity by a factor of 5.87 relative to the azimuth angle of 0 deg.

[1]  J. Homola.  Present and future of surface plasmon resonance biosensors , 2003, Analytical and bioanalytical chemistry.

[2]  X. D. Hoa,et al.  Towards integrated and sensitive surface plasmon resonance biosensors: a review of recent progress. , 2007, Biosensors & bioelectronics.

[3]  Marvin J. Weber,et al.  Handbook of Optical Materials , 2002 .

[4]  Sergiy Patskovsky,et al.  Phase and amplitude sensitivities in surface plasmon resonance bio and chemical sensing. , 2009, Optics express.

[5]  Jiří Homola,et al.  Rich information format surface plasmon resonance biosensor based on array of diffraction gratings , 2005 .

[6]  G Ruffato,et al.  Sensitivity enhancement in grating coupled surface plasmon resonance by azimuthal control. , 2009, Optics express.

[7]  J. Brockman,et al.  Grating-coupled surface plasmon resonance for rapid, label-free, array-based sensing , 2001 .

[8]  Salvador M. Fernandez,et al.  Grating‐coupled surface plasmon resonance: A cell and protein microarray platform , 2005, Proteomics.

[9]  Wen-Kai Kuo,et al.  Phase detection properties of grating-coupled surface plasmon resonance sensors. , 2010, Optics express.

[10]  Sung June Kim,et al.  Design optimization of nano-grating surface plasmon resonance sensors. , 2006, Optics express.

[11]  Donghyun Kim,et al.  Effect of the azimuthal orientation on the performance of grating-coupled surface-plasmon resonance biosensors. , 2005, Applied optics.

[12]  H. Raether.  Surface Plasmons on Smooth and Rough Surfaces and on Gratings , 1988 .

[13]  T Turbadar,et al.  Complete Absorption of Light by Thin Metal Films , 1959 .

[14]  Jiří Homola,et al.  Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison , 1999 .

[15]  D. Furlong,et al.  Surface plasmon resonance studies of immunoreactions utilizing disposable diffraction gratings. , 1996, Biosensors & bioelectronics.

[16]  Kun-Huang Chen,et al.  Measurement of wavelength shift by using surface plasmon resonance heterodyne interferometry , 2002 .