In vivo depth heterogeneity of the abdomen assessed by broadband time-domain diffuse optical spectroscopy

We investigated depth heterogeneity in the abdomen using time-domain diffuse optical spectroscopy at 3 source-detector distances, finding a higher water content in shallower regions, possibly ascribed to fat heterogeneity and/or skin contributions.

[1]  Davide Contini,et al.  Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity. , 2015, Biomedical optics express.

[2]  Paola Taroni,et al.  In Vivo, Non-Invasive Characterization of Human Bone by Hybrid Broadband (600-1200 nm) Diffuse Optical and Correlation Spectroscopies , 2016, PloS one.

[3]  A. Pifferi,et al.  Time-resolved single-photon detection module based on silicon photomultiplier: A novel building block for time-correlated measurement systems. , 2016, The Review of scientific instruments.

[4]  S. Cinti,et al.  Convertible visceral fat as a therapeutic target to curb obesity , 2016, Nature Reviews Drug Discovery.

[5]  Bruce J. Tromberg,et al.  Diffuse optical spectroscopic imaging of subcutaneous adipose tissue metabolic changes during weight loss , 2016, International Journal of Obesity.

[6]  Davide Contini,et al.  New frontiers in time-domain diffuse optics, a review , 2016, Journal of biomedical optics.

[7]  S. Devaraj,et al.  Adipose tissue dysregulation in patients with metabolic syndrome. , 2011, The Journal of clinical endocrinology and metabolism.

[8]  Alessandro Torricelli,et al.  There’s plenty of light at the bottom: statistics of photon penetration depth in random media , 2016, Scientific Reports.

[9]  Davide Contini,et al.  Diffuse optics using a dual window fast-gated counter. , 2014, Applied optics.

[10]  Andrea Farina,et al.  Time-domain diffuse optical tomography using silicon photomultipliers: feasibility study , 2016, Journal of biomedical optics.

[11]  G. Boso,et al.  Functional near-infrared spectroscopy at small source-detector distance by means of high dynamic-range fast-gated SPAD acquisitions: first in-vivo measurements , 2013, European Conference on Biomedical Optics.

[12]  Paola Taroni,et al.  Broadband (600–1350 nm) Time-Resolved Diffuse Optical Spectrometer for Clinical Use , 2016, IEEE Journal of Selected Topics in Quantum Electronics.