Primase promotes the competition between transcription and replication on the same template strand resulting in DNA damage
暂无分享,去创建一个
[1] Qianwen Sun,et al. DNA polymerase ε harmonizes topological states and R-loops formation to maintain genome integrity in Arabidopsis , 2023, Nature communications.
[2] Qianwen Sun,et al. DEtail-seq is an ultra-efficient and convenient method for meiotic DNA break profiling in multiple organisms , 2023, Science China Life Sciences.
[3] Wenzhi Lan,et al. Two Magnesium Transporters in the Chloroplast Inner Envelope Essential for Thylakoid Biogenesis in Arabidopsis. , 2022, The New phytologist.
[4] Zhongnan Yang,et al. AtNusG, a chloroplast nucleoid protein of bacterial origin linking chloroplast transcriptional and translational machineries, is required for proper chloroplast gene expression in Arabidopsis thaliana , 2022, Nucleic acids research.
[5] K. Cimprich,et al. Walking a tightrope: The complex balancing act of R-loops in genome stability. , 2022, Molecular cell.
[6] Xueming Li,et al. Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids , 2022, bioRxiv.
[7] D. Garboczi,et al. Structural basis of R-loop recognition by the S9.6 monoclonal antibody , 2022, Nature Communications.
[8] Qianwen Sun,et al. Mitochondrial RNase H1 activity regulates R-loop homeostasis to maintain genome integrity and enable early embryogenesis in Arabidopsis , 2021, PLoS biology.
[9] Qianwen Sun,et al. RNase H1C collaborates with ssDNA binding proteins WHY1/3 and recombinase RecA1 to fulfill the DNA damage repair in Arabidopsis chloroplasts , 2021, Nucleic acids research.
[10] Uttiya Basu,et al. Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells , 2021, Nature Genetics.
[11] Qianwen Sun,et al. RHON1 Co-transcriptionally Resolves R-Loops for Arabidopsis Chloroplast Genome Maintenance. , 2020, Cell reports.
[12] J. Gualberto,et al. DNA Repair and the Stability of the Plant Mitochondrial Genome , 2020, International journal of molecular sciences.
[13] A. Aguilera,et al. R Loops: From Physiological to Pathological Roles , 2019, Cell.
[14] N. Ahmad,et al. Plant Organelle Genome Replication , 2019, Plants.
[15] P. Ridge,et al. Arabidopsis thaliana organelles mimic the T7 phage DNA replisome with specific interactions between Twinkle protein and DNA polymerases Pol1A and Pol1B , 2019, BMC Plant Biology.
[16] Iain G. Johnston,et al. Tension and Resolution: Dynamic, Evolving Populations of Organelle Genomes within Plant Cells. , 2019, Molecular plant.
[17] A. Aguilera,et al. Transcription-mediated replication hindrance: a major driver of genome instability , 2019, Genes & development.
[18] S. Nik-Zainal,et al. Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts , 2019, bioRxiv.
[19] K. Cimprich,et al. R-Loops as Cellular Regulators and Genomic Threats. , 2019, Molecular cell.
[20] Wei Xu,et al. RNase H1 Cooperates with DNA Gyrases to Restrict R-Loops and Maintain Genome Integrity in Arabidopsis Chloroplasts , 2017, Plant Cell.
[21] L. Brieba,et al. Plant organellar DNA primase-helicase synthesizes RNA primers for organellar DNA polymerases using a unique recognition sequence , 2017, Nucleic acids research.
[22] Wei Xu,et al. The R-loop is a common chromatin feature of the Arabidopsis genome , 2017, Nature Plants.
[23] Hannah Tabakh,et al. Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis , 2017, Cell.
[24] T. Swigut,et al. Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses , 2017, Cell.
[25] H. Merrikh,et al. Spatial and Temporal Control of Evolution through Replication-Transcription Conflicts. , 2017, Trends in microbiology.
[26] T. Kuroiwa,et al. Holliday junction resolvases mediate chloroplast nucleoid segregation , 2017, Science.
[27] R. Rabadán,et al. Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry , 2017, Cell.
[28] W. Smits,et al. Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile , 2016, Open Biology.
[29] T. Kunkel,et al. Processing ribonucleotides incorporated during eukaryotic DNA replication , 2016, Nature Reviews Molecular Cell Biology.
[30] P. Hanawalt,et al. Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair , 2016, Cell.
[31] M. Falkenberg,et al. Primer removal during mammalian mitochondrial DNA replication. , 2015, DNA repair.
[32] Xuecheng Wang,et al. Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation , 2015, Genome Biology.
[33] Martin A. M. Reijns,et al. Lagging strand replication shapes the mutational landscape of the genome , 2015, Nature.
[34] A. Bhagwat,et al. Transcription-associated mutagenesis. , 2014, Annual review of genetics.
[35] Junhong Han,et al. Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall. , 2014, Molecular cell.
[36] D. L. Thurlow,et al. Chimeric proteins constructed from bacteriophage T7 gp4 and a putative primase–helicase from Arabidopsis thaliana , 2014, Molecular Biology Reports.
[37] David Hsu,et al. OpenComet: An automated tool for comet assay image analysis , 2014, Redox biology.
[38] B. Liu,et al. The Arabidopsis At1g30680 gene encodes a homologue to the phage T7 gp4 protein that has both DNA primase and DNA helicase activities , 2013, BMC Plant Biology.
[39] C. Richardson,et al. Molecular interactions in the priming complex of bacteriophage T7 , 2012, Proceedings of the National Academy of Sciences.
[40] C. Richardson,et al. Choreography of bacteriophage T7 DNA replication. , 2011, Current opinion in chemical biology.
[41] Jean-Sébastien Parent,et al. Divergent Roles for the Two PolI-Like Organelle DNA Polymerases of Arabidopsis1[W][OA] , 2011, Plant Physiology.
[42] P. Polak,et al. The evolution of transcription-associated biases of mutations across vertebrates , 2010, BMC Evolutionary Biology.
[43] S. Hamdan,et al. Motors, switches, and contacts in the replisome. , 2009, Annual review of biochemistry.
[44] C. Gustafsson,et al. Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro , 2008, Proceedings of the National Academy of Sciences.
[45] A. Weber,et al. The origin and establishment of the plastid in algae and plants. , 2007, Annual review of genetics.
[46] S. Benkovic,et al. Real-time observation of bacteriophage T4 gp41 helicase reveals an unwinding mechanism , 2007, Proceedings of the National Academy of Sciences.
[47] X. Xie,et al. DNA primase acts as a molecular brake in DNA replication , 2006, Nature.
[48] A. Paetau,et al. Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[49] Christian G Elowsky,et al. Dual-Domain, Dual-Targeting Organellar Protein Presequences in Arabidopsis Can Use Non-AUG Start Codons , 2005, The Plant Cell Online.
[50] Toyotaka Ishibashi,et al. Plastid DNA polymerases from higher plants, Arabidopsis thaliana. , 2005, Biochemical and biophysical research communications.
[51] C. van Broeckhoven,et al. Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA. , 2004, Nucleic acids research.
[52] N. Seeman. DNA in a material world , 2003, Nature.
[53] G. Comi,et al. Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria , 2001, Nature Genetics.
[54] S. Hyberts,et al. The Cys4 zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[55] M. Kunnimalaiyaan,et al. Fine mapping of replication origins (ori A and ori B) in Nicotiana tabacum chloroplast DNA. , 1997, Nucleic acids research.
[56] K. Yoda,et al. Evidence that discontinuous DNA replication in Escherichia coli is primed by approximately 10 to 12 residues of RNA starting with a purine. , 1985, Journal of molecular biology.