Deep Dermatophytosis to Trichophyton rubrum and T. verrucosum in an Immunosuppressed Patient

ABSTRACT: A patient treated with immunosuppressant drug therapy for a non‐Hodgkin's lymphoma and who presented with a tinea corporis developed a sudden outbreak of numerous subcutaneous nodules. Deep‐seated hyphae and spores were found in skin biopsy specimens. There was no evidence of keratin debris or histologic features of granulomata and giant cells. Cultures from tinea and nodules grew Trichophyton rubrum and T. verrucosum. There are no more than 60 cases of deep dermatophytosis reported in the literature.

[1]  E. Bottone,et al.  Invasive trichophyton rubrum infection in an immunocompromised host. Case report and review of the literature. , 1987, The American journal of medicine.

[2]  H. Tiouiri,et al.  La maladie dermatophytique, à propos d'un cas tunisien , 1987 .

[3]  M. Para,et al.  Successful use of ketoconazole for invasive cutaneous Trichophyton rubrum infection. , 1984, Archives of internal medicine.

[4]  B. Liautaud,et al.  La maladie dermatophytique observations Algériennes récentes , 1984 .

[5]  N. Okazaki,et al.  Trichophyton mentagrophytes granulomas. Unique systemic dissemination to lymph nodes, testes, vertebrae, and brain. , 1983, Archives of dermatology.

[6]  Z. Brahmi,et al.  Depressed cell-mediated immunity in chronic dermatophytic infections. , 1978, Archives de l'Institut Pasteur d'Algerie. Institut Pasteur d'Algerie.

[7]  K. Márton,et al.  MYCOSE GENERALISEE DUE AU TRICHOPHYTON VERRUCOSUM: A PROPOS DE DEUX CAS , 1973 .

[8]  E. Thorne,et al.  Subcutaneous Trichophyton rubrum abscesses. A case report. , 1971, Dermatologica.

[9]  G. Catanzano,et al.  [A recent case of "dermatophytic disease": epidermomycosis (T. violaceum) with dermoepidermal localizations]. , 1970, Maroc medical.

[10]  J. Convit,et al.  Subcutaneous abscesses caused by T. rubrum. , 1970 .

[11]  H. Blank,et al.  Widespread Trichophyton rubrum granulomas treated with griseofulvin. , 1960, Archives of dermatology.

[12]  H. Blank,et al.  The pathogenesis of superficial fungous infections in cultured human skin. , 1959, A.M.A. archives of dermatology.

[13]  T. Sternberg,et al.  Deep infection of mice with Trichophyton rubrum (purpureum). , 1952, The Journal of investigative dermatology.

[14]  J. Sequeira.  A CASE OF TRICHOPHYTIC GRANULOMATA , 1912 .