IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain.
暂无分享,去创建一个
[1] W. Paul,et al. Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor. , 1996, Immunity.
[2] William Arbuthnot Sir Lane,et al. Role of IRS-2 in insulin and cytokine signalling , 1995, Nature.
[3] W. Paul,et al. Interleukin 4 signals through two related pathways. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[4] J. Darnell,et al. Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation , 1995, Cell.
[5] N. Stahl,et al. STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[6] L. Ivashkiv. Cytokines and STATs: how can signals achieve specificity? , 1995, Immunity.
[7] B. Groner,et al. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[8] S. McKnight,et al. Components of a Stat recognition code: evidence for two layers of molecular selectivity. , 1995, Immunity.
[9] R. Schreiber,et al. Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. , 1995, Immunity.
[10] W. Paul,et al. Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis , 1995, Molecular and cellular biology.
[11] W. Leonard,et al. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. , 1995, Immunity.
[12] J. Blenis,et al. Requirement of serine phosphorylation for formation of STAT-promoter complexes. , 1995, Science.
[13] J. Darnell,et al. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors , 1995, Science.
[14] J. Darnell,et al. Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway , 1995, Science.
[15] E. Skolnik,et al. Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin , 1995, Molecular and cellular biology.
[16] H. Fujii. Activation of Stat5 by interleukin 2 requires a carboxy-terminal region β chain but is not exxential for the proliferative signal transdution. , 1995 .
[17] J. Blenis,et al. Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation. , 1994, The Journal of biological chemistry.
[18] O. Silvennoinen,et al. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. , 1994, Science.
[19] J. Johnston,et al. Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID. , 1994, Science.
[20] Y. Yang,et al. JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes. , 1994, The Journal of biological chemistry.
[21] T. O’Neill,et al. Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system , 1994, Molecular and cellular biology.
[22] S. McKnight,et al. An interleukin-4-induced transcription factor: IL-4 Stat. , 1994, Science.
[23] W. Paul,et al. Interleukin 4 receptor: signaling mechanisms. , 1994, Immunology today.
[24] E. Liu,et al. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells , 1994, Nature.
[25] J. Johnston,et al. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2 , 1994, Nature.
[26] J. Darnell,et al. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. , 1994, Science.
[27] D. Cosman,et al. Utilization of the beta and gamma chains of the IL‐2 receptor by the novel cytokine IL‐15. , 1994, The EMBO journal.
[28] M. White,et al. Role of IRS-1-GRB-2 complexes in insulin signaling , 1994, Molecular and cellular biology.
[29] M. Goldsmith,et al. The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements. , 1994, The Journal of biological chemistry.
[30] B. Viviano,et al. Ligand‐induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). , 1994, The EMBO journal.
[31] D. Katz,et al. Regulation of the murine Fc epsilon RII (CD23) gene. Functional characterization of an IL-4 enhancer element. , 1994, Journal of immunology.
[32] W. Paul,et al. An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth , 1994, Cell.
[33] S. Nishikawa,et al. Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes. , 1994, Science.
[34] C. Schindler,et al. STF‐IL‐4: a novel IL‐4‐induced signal transducing factor. , 1994, The EMBO journal.
[35] C. Kahn,et al. The insulin signaling system. , 1994, The Journal of biological chemistry.
[36] S. Ziegler,et al. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. , 1993, Science.
[37] K. Arai,et al. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. , 1993, Science.
[38] E. Rieber,et al. Allergy‐associated Iϵ and Fcϵ receptor II (CD23b) genes activated via binding of an interleukin‐4‐induced transcription factor to a novel responsive element , 1993 .
[39] N. Reich,et al. Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. , 1993, Science.
[40] M. White,et al. IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells. , 1993, Science.
[41] K. Izuhara,et al. Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2. , 1993, The Journal of biological chemistry.
[42] A. Ullrich,et al. The SH2/SH3 domain‐containing protein GRB2 interacts with tyrosine‐phosphorylated IRS1 and Shc: implications for insulin control of ras signalling. , 1993, The EMBO journal.
[43] G. Lienhard,et al. Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[44] T. Taniguchi,et al. The IL-2 IL-2 receptor system: A current overview , 1993, Cell.
[45] D. Cosman. The hematopoietin receptor superfamily. , 1993, Cytokine.
[46] J. Gutkind,et al. IL‐4 activates a distinct signal transduction cascade from IL‐3 in factor‐dependent myeloid cells. , 1992, The EMBO journal.
[47] V. Duronio,et al. Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members. , 1992, Journal of immunology.
[48] N. Tanaka,et al. Cloning of the gamma chain of the human IL-2 receptor. , 1992, Science.
[49] W. Paul,et al. Interleukin-4 : A Prototypic Immunoregulatory Lymphokine , 2003 .
[50] M. Nakafuku,et al. Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[51] J. Banchereau,et al. Molecular cloning of a cDNA encoding the human interleukin 4 receptor. , 1990, International immunology.
[52] C. March,et al. Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily , 1990, The Journal of experimental medicine.
[53] R. Higuchi. 22 – RECOMBINANT PCR , 1990 .
[54] T. Taniguchi,et al. A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization , 1989, Cell.
[55] A. Ullrich,et al. Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity , 1988, Cell.
[56] J. Wang,et al. Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3-dependent murine cell lines , 1988, Molecular and cellular biology.
[57] J. Coligan,et al. High-efficiency purification and chemical characterization of B cell stimulatory factor-1/interleukin 4. , 1987, Journal of immunology.