Immunosurveillance of senescent cells: the bright side of the senescence program

[1]  J. Lord,et al.  The impact of ageing on natural killer cell function and potential consequences for health in older adults , 2013, Ageing Research Reviews.

[2]  Darjus F. Tschaharganeh,et al.  Non-Cell-Autonomous Tumor Suppression by p53 , 2013, Cell.

[3]  J. Campisi.  Aging, cellular senescence, and cancer. , 2013, Annual review of physiology.

[4]  L. Zender,et al.  T-helper-1-cell cytokines drive cancer into senescence , 2013, Nature.

[5]  D. Baker,et al.  Senescent Cells: A Novel Therapeutic Target for Aging and Age‐Related Diseases , 2013, Clinical pharmacology and therapeutics.

[6]  S. Lowe,et al.  Granule exocytosis mediates immune surveillance of senescent cells , 2012, Oncogene.

[7]  B. Pützer,et al.  Senescence determines the fate of activated rat pancreatic stellate cells , 2012, Journal of cellular and molecular medicine.

[8]  Alberto Mantovani,et al.  Macrophage plasticity and polarization: in vivo veritas. , 2012, The Journal of clinical investigation.

[9]  T. Luedde,et al.  Senescence surveillance of pre-malignant hepatocytes limits liver cancer development , 2011, Nature.

[10]  N. LeBrasseur,et al.  Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders , 2011, Nature.

[11]  E. Pamer,et al.  Monocyte recruitment during infection and inflammation , 2011, Nature Reviews Immunology.

[12]  Xiaowo Wang,et al.  Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity. , 2011, Genes & development.

[13]  T. Wynn,et al.  Protective and pathogenic functions of macrophage subsets , 2011, Nature Reviews Immunology.

[14]  M. Ingersoll,et al.  Monocyte trafficking in acute and chronic inflammation. , 2011, Trends in immunology.

[15]  E. K. Parkinson,et al.  Senescent mesenchymal cells accumulate in human fibrosis by a telomere‐independent mechanism and ameliorate fibrosis through matrix metalloproteinases , 2011, The Journal of pathology.

[16]  C. Akdis,et al.  Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases. , 2011, The Journal of allergy and clinical immunology.

[17]  D. Peeper,et al.  The essence of senescence. , 2010, Genes & development.

[18]  L. Lau,et al.  The Matricellular Protein CCN1/CYR61 Induces Fibroblast Senescence and Restricts Fibrosis in Cutaneous Wound Healing , 2010, Nature Cell Biology.

[19]  J. Campisi,et al.  Inflammatory networks during cellular senescence: causes and consequences. , 2010, Trends in molecular medicine.

[20]  W. Paul,et al.  Differentiation of effector CD4 T cell populations (*). , 2010, Annual review of immunology.

[21]  E. Maris,et al.  Two Sides of the Same Coin , 2010, Psychological science.

[22]  J. Campisi,et al.  The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.

[23]  F. Geissmann,et al.  Monocytes in atherosclerosis: subsets and functions , 2010, Nature Reviews Cardiology.

[24]  M. Serrano,et al.  Senescence in tumours: evidence from mice and humans , 2010, Nature Reviews Cancer.

[25]  P. Adams.  Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence. , 2009, Molecular cell.

[26]  R. Foà,et al.  ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. , 2009, Blood.

[27]  Simon Tavaré,et al.  Autophagy mediates the mitotic senescence transition. , 2009, Genes & development.

[28]  Dominick G. A. Burton.  Cellular senescence, ageing and disease , 2009, AGE.

[29]  Judith Campisi,et al.  Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor , 2008, PLoS biology.

[30]  Mark J. Smyth,et al.  The TRAIL apoptotic pathway in cancer onset, progression and therapy , 2008, Nature Reviews Cancer.

[31]  S. Bromley,et al.  Orchestrating the orchestrators: chemokines in control of T cell traffic , 2008, Nature Immunology.

[32]  S. Lowe,et al.  Senescence of Activated Stellate Cells Limits Liver Fibrosis , 2008, Cell.

[33]  S. Cullen,et al.  Mechanisms of granule-dependent killing , 2008, Cell Death and Differentiation.

[34]  J. Campisi,et al.  Cellular senescence: when bad things happen to good cells , 2007, Nature Reviews Molecular Cell Biology.

[35]  M. Blasco,et al.  Cellular Senescence in Cancer and Aging , 2007, Cell.

[36]  J. Bernhagen,et al.  MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment , 2007, Nature Medicine.

[37]  Carlos Cordon-Cardo,et al.  Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas , 2007, Nature.

[38]  K. Ligon,et al.  p16INK4a induces an age-dependent decline in islet regenerative potential , 2006, Nature.

[39]  R. DePinho,et al.  Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a , 2006, Nature.

[40]  S. Morrison,et al.  Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing , 2006, Nature.

[41]  M. Smyth,et al.  NKG2D and cytotoxic effector function in tumor immune surveillance. , 2006, Seminars in immunology.

[42]  M. Caligiuri,et al.  Human natural killer cell development and biology. , 2006, Blood reviews.

[43]  J. Sedivy,et al.  Cellular Senescence in Aging Primates , 2006, Science.

[44]  R. Ransohoff,et al.  The many roles of chemokines and chemokine receptors in inflammation. , 2006, The New England journal of medicine.

[45]  S. Gordon,et al.  Monocyte and macrophage heterogeneity , 2005, Nature Reviews Immunology.

[46]  M. Barbacid,et al.  Tumour biology: Senescence in premalignant tumours , 2005, Nature.

[47]  J. Shay,et al.  BRAFE600-associated senescence-like cell cycle arrest of human naevi , 2005, Nature.

[48]  H. Stein,et al.  Oncogene-induced senescence as an initial barrier in lymphoma development , 2005, Nature.

[49]  Jason A. Koutcher,et al.  Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis , 2005, Nature.

[50]  Lewis L Lanier,et al.  NK cell recognition. , 2005, Annual review of immunology.

[51]  K. Kuwano,et al.  The perforin mediated apoptotic pathway in lung injury and fibrosis , 2004, Journal of Clinical Pathology.

[52]  F. Pixley,et al.  CSF-1 regulation of the wandering macrophage: complexity in action. , 2004, Trends in cell biology.

[53]  K. Ley,et al.  Trafficking of natural killer cells. , 2004, Current molecular medicine.

[54]  G. Matarese,et al.  The weight of leptin in immunity , 2004, Nature Reviews Immunology.

[55]  B. McManus,et al.  Granzyme B in Atherosclerosis and Transplant Vascular Disease: Association with Cell Death and Atherosclerotic Disease Severity , 2003, Modern Pathology.

[56]  D. Brenner,et al.  Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype , 2003, Hepatology.

[57]  D. Link,et al.  G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. , 2002, Immunity.

[58]  Michael Loran Dustin,et al.  T-cell activation: a multidimensional signaling network. , 2002, Current opinion in cell biology.

[59]  T. Geijtenbeek,et al.  DC‐SIGN, a C‐type lectin on dendritic cells that unveils many aspects of dendritic cell biology , 2002, Journal of leukocyte biology.

[60]  R. Bleackley,et al.  Cytotoxic T lymphocytes: all roads lead to death , 2002, Nature Reviews Immunology.

[61]  Soyoung Lee,et al.  A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy , 2002, Cell.

[62]  S. Joel,et al.  DNA damage is able to induce senescence in tumor cells in vitro and in vivo. , 2002, Cancer research.

[63]  A. Luster.  The role of chemokines in linking innate and adaptive immunity. , 2002, Current opinion in immunology.

[64]  P. Romero.  Faculty Opinions recommendation of NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment. , 2002 .

[65]  Arthur I. Roberts,et al.  Cutting Edge: NKG2D Receptors Induced by IL-15 Costimulate CD28-Negative Effector CTL in the Tissue Microenvironment1 , 2001, The Journal of Immunology.

[66]  W. Pichler,et al.  Perforin and granzyme B may contribute to skin inflammation in atopic dermatitis and psoriasis , 2001, The British journal of dermatology.

[67]  C. Mackay,et al.  T-cell function and migration. Two sides of the same coin. , 2000, The New England journal of medicine.

[68]  U. Syrbe,et al.  T-cell trafficking into sites of inflammation. , 2000, Rheumatology.

[69]  C. Murdoch,et al.  Chemokine receptors and their role in inflammation and infectious diseases. , 2000, Blood.

[70]  D. Link,et al.  A role for G-CSF receptor signaling in the regulation of hematopoietic cell function but not lineage commitment or differentiation. , 1999, Immunity.

[71]  R. Rabin,et al.  Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. , 1999, Journal of immunology.

[72]  A. O’Garra,et al.  Cytokines induce the development of functionally heterogeneous T helper cell subsets. , 1998, Immunity.

[73]  C Roskelley,et al.  A biomarker that identifies senescent human cells in culture and in aging skin in vivo. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[74]  L. Hayflick,et al.  The serial cultivation of human diploid cell strains. , 1961, Experimental cell research.