Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

[1]  Alicia R. Martin,et al.  Identification of common genetic risk variants for autism spectrum disorder , 2019, Nature Genetics.

[2]  Lachlan T. Strike,et al.  Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group , 2018, bioRxiv.

[3]  Alicia R. Martin,et al.  Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder , 2018, Nature Genetics.

[4]  A. Uitterlinden,et al.  DNA methylation signatures of educational attainment , 2018, npj Science of Learning.

[5]  Sina A. Gharib,et al.  Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood , 2018, Nature Communications.

[6]  Yankai Xia,et al.  Prenatal exposure to maternal smoking during pregnancy and attention-deficit/hyperactivity disorder in offspring: A meta-analysis. , 2018, Reproductive toxicology.

[7]  Warren W. Kretzschmar,et al.  Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression , 2017, Nature Genetics.

[8]  Tom R. Gaunt,et al.  A Methylome‐Wide Association Study of Trajectories of Oppositional Defiant Behaviors and Biological Overlap With Attention Deficit Hyperactivity Disorder , 2017, Child development.

[9]  W. Iacono,et al.  Increased Risk of Smoking in Female Adolescents Who Had Childhood ADHD. , 2018, The American journal of psychiatry.

[10]  Min A. Jhun,et al.  Meta-analysis of epigenome-wide association studies of cognitive abilities , 2018, Molecular Psychiatry.

[11]  Jakob Grove,et al.  Common risk variants identified in autism spectrum disorder , 2017, bioRxiv.

[12]  R. Joober,et al.  Locus-specific DNA methylation changes and phenotypic variability in children with attention-deficit hyperactivity disorder , 2017, Psychiatry Research.

[13]  R. Lyle,et al.  Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD , 2017, Clinical Epigenetics.

[14]  M. Beckmann,et al.  Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age , 2017, Scientific Reports.

[15]  G. Reynolds,et al.  DAT1 methylation is associated with methylphenidate response on oppositional and hyperactive-impulsive symptoms in children and adolescents with ADHD , 2017, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[16]  Daniel P. Newman,et al.  Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study , 2017, Molecular Psychiatry.

[17]  M. Kobor,et al.  BECon: a tool for interpreting DNA methylation findings from blood in the context of brain , 2017, Translational Psychiatry.

[18]  Tom R. Gaunt,et al.  Prenatal unhealthy diet, insulin‐like growth factor 2 gene (IGF2) methylation, and attention deficit hyperactivity disorder symptoms in youth with early‐onset conduct problems , 2016, Journal of child psychology and psychiatry, and allied disciplines.

[19]  A. Hofman,et al.  Disease variants alter transcription factor levels and methylation of their binding sites , 2016, Nature Genetics.

[20]  Alan M. Zaslavsky,et al.  The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys , 2017, ADHD Attention Deficit and Hyperactivity Disorders.

[21]  A. Sharp,et al.  DNA Methylation Signatures of Early Childhood Malnutrition Associated With Impairments in Attention and Cognition , 2016, Biological Psychiatry.

[22]  Paolo Vineis,et al.  Epigenetic Signatures of Cigarette Smoking , 2016, Circulation. Cardiovascular genetics.

[23]  V. Faundez,et al.  The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin , 2016, Front. Cell. Neurosci..

[24]  Robin M. Murray,et al.  An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation , 2016, Genome Biology.

[25]  A. Danese,et al.  Evaluation of the Persistence, Remission, and Emergence of Attention-Deficit/Hyperactivity Disorder in Young Adulthood. , 2016, JAMA psychiatry.

[26]  A. Hofman,et al.  Blood lipids influence DNA methylation in circulating cells , 2016, Genome Biology.

[27]  B. Franke,et al.  Whole-Exome Sequencing Reveals Increased Burden of Rare Functional and Disruptive Variants in Candidate Risk Genes in Individuals With Persistent Attention-Deficit/Hyperactivity Disorder. , 2016, Journal of the American Academy of Child and Adolescent Psychiatry.

[28]  P. Eline Slagboom,et al.  Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution , 2016, bioRxiv.

[29]  Tom R. Gaunt,et al.  Epigenetic profiling of ADHD symptoms trajectories: A prospective, methylome-wide study , 2016, Molecular Psychiatry.

[30]  Charles Auffray,et al.  DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. , 2016, American journal of human genetics.

[31]  E. Garne,et al.  Fever and infections in pregnancy and risk of attention deficit/hyperactivity disorder in the offspring. , 2016, Journal of child psychology and psychiatry, and allied disciplines.

[32]  A. Uitterlinden,et al.  Genetic and environmental influences interact with age and sex in shaping the human methylome , 2016, Nature Communications.

[33]  Jingyu Liu,et al.  Correspondence of DNA Methylation Between Blood and Brain Tissue and Its Application to Schizophrenia Research. , 2016, Schizophrenia bulletin.

[34]  M. Dadds,et al.  Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children , 2016, European Child & Adolescent Psychiatry.

[35]  Sarah E. Reese,et al.  Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns , 2016, Nature Communications.

[36]  J. Nigg,et al.  Methylomic analysis of salivary DNA in childhood ADHD identifies altered DNA methylation in VIPR2. , 2016, Journal of child psychology and psychiatry, and allied disciplines.

[37]  Giulio Genovese,et al.  Schizophrenia risk from complex variation of complement component 4 , 2016, Nature.

[38]  J. Mill,et al.  Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes , 2015, Epigenetics.

[39]  J. Cheong,et al.  Associations between serotonin transporter gene (SLC6A4) methylation and clinical characteristics and cortical thickness in children with ADHD , 2015, Psychological Medicine.

[40]  D. Belsky,et al.  Is Adult ADHD a Childhood-Onset Neurodevelopmental Disorder? Evidence From a Four-Decade Longitudinal Cohort Study. , 2015, The American journal of psychiatry.

[41]  Bin-Rang Yang,et al.  Multiple epigenetic factors predict the attention deficit/hyperactivity disorder among the Chinese Han children. , 2015, Journal of psychiatric research.

[42]  Tiphaine C. Martin,et al.  coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns , 2015, BMC Bioinformatics.

[43]  M. Daly,et al.  An Atlas of Genetic Correlations across Human Diseases and Traits , 2015, Nature Genetics.

[44]  Richie Poulton,et al.  The Dunedin Multidisciplinary Health and Development Study: overview of the first 40 years, with an eye to the future , 2015, Social Psychiatry and Psychiatric Epidemiology.

[45]  P. Elliott,et al.  A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies , 2015, Genome Biology.

[46]  P. Eline Slagboom,et al.  MethylAid: visual and interactive quality control of large Illumina 450k datasets , 2014, Bioinform..

[47]  B. Neale,et al.  Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children. , 2014, Journal of the American Academy of Child and Adolescent Psychiatry.

[48]  C. Spencer,et al.  Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.

[49]  Pieter B. T. Neerincx,et al.  Supplementary Information Whole-genome sequence variation , population structure and demographic history of the Dutch population , 2022 .

[50]  K. Hansen,et al.  Functional normalization of 450k methylation array data improves replication in large cancer studies , 2014, Genome Biology.

[51]  A. Hofman,et al.  DNA methylation profiles at birth and child ADHD symptoms. , 2014, Journal of psychiatric research.

[52]  Nicholas G Martin,et al.  Contribution of genetic variation to transgenerational inheritance of DNA methylation , 2014, Genome Biology.

[53]  Eric-Wubbo Lameijer,et al.  Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array , 2013, Epigenetics & Chromatin.

[54]  Ruth Pidsley,et al.  A data-driven approach to preprocessing Illumina 450K methylation array data , 2013, BMC Genomics.

[55]  P. Sullivan,et al.  Population structure, migration, and diversifying selection in the Netherlands , 2013, European Journal of Human Genetics.

[56]  P. Lichtenstein,et al.  Developmental twin study of attention problems: high heritabilities throughout development. , 2013, JAMA psychiatry.

[57]  R. Weksberg,et al.  Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray , 2013, Epigenetics.

[58]  H. M. Draisma,et al.  The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection , 2013, Twin Research and Human Genetics.

[59]  A. Thapar,et al.  Practitioner Review: What have we learnt about the causes of ADHD? , 2013, Journal of Child Psychology and Psychiatry, and Allied Disciplines.

[60]  Pau Farré,et al.  Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array , 2013, Epigenetics & Chromatin.

[61]  Brent S. Pedersen,et al.  Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values , 2012, Bioinform..

[62]  Devin C. Koestler,et al.  DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.

[63]  P. Lichtenstein,et al.  Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs. , 2012, Journal of child psychology and psychiatry, and allied disciplines.

[64]  Catharina E. M. van Beijsterveldt,et al.  Evidence for a causal association of low birth weight and attention problems. , 2011, Journal of the American Academy of Child and Adolescent Psychiatry.

[65]  Jennifer R Harris,et al.  Extensive variation and low heritability of DNA methylation identified in a twin study. , 2011, Genome research.

[66]  R. Kessler,et al.  Structure and diagnosis of adult attention-deficit/hyperactivity disorder: analysis of expanded symptom criteria from the Adult ADHD Clinical Diagnostic Scale. , 2010, Archives of general psychiatry.

[67]  P. Greengard,et al.  AGAP1/AP‐3‐dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release , 2010, The EMBO journal.

[68]  Yun Li,et al.  METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..

[69]  T. Lehner,et al.  The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies , 2010, Twin Research and Human Genetics.

[70]  G. Willemsen,et al.  Genetic Epidemiology of Attention Deficit Hyperactivity Disorder (ADHD Index) in Adults , 2010, PloS one.

[71]  Hein Putter,et al.  Persistent epigenetic differences associated with prenatal exposure to famine in humans , 2008, Proceedings of the National Academy of Sciences.

[72]  Arturas Petronis,et al.  Pre- and peri-natal environmental risks for attention-deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility. , 2008, Journal of child psychology and psychiatry, and allied disciplines.

[73]  R. Barkley,et al.  ADHD in Adults: What the Science Says , 2007 .

[74]  L. Rohde,et al.  Epidemiology of attention-deficit/hyperactivity disorder across the lifespan , 2007, Current opinion in psychiatry.

[75]  C. Moore,et al.  Prevalence and Correlates of ADHD Symptoms in the National Health Interview Survey , 2005, Journal of attention disorders.

[76]  K. Macey.  Conners' Adult ADHD Rating Scales (CAARS). , 2003 .

[77]  T. Moffitt.  Teen-aged mothers in contemporary Britain. , 2002, Journal of child psychology and psychiatry, and allied disciplines.

[78]  M. Jeanpierre.  A rapid method for the purification of DNA from blood. , 1987, Nucleic acids research.

[79]  D. Bowtell,et al.  Rapid isolation of eukaryotic DNA. , 1987, Analytical biochemistry.