Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity.

[1]  P. Eyer,et al.  Reversible inhibition of acetylcholinesterase by carbamates or huperzine A increases residual activity of the enzyme upon soman challenge. , 2007, Toxicology.

[2]  P. Eyer,et al.  Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds. , 2006, Biochemical pharmacology.

[3]  P. Eyer,et al.  Development of a dynamic model for real-time determination of membrane-bound acetylcholinesterase activity upon perfusion with inhibitors and reactivators. , 2006, Biochemical pharmacology.

[4]  P. Eyer,et al.  Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes. , 2004, Biochemical pharmacology.

[5]  P. Eyer,et al.  Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates , 2002, Archives of Toxicology.

[6]  P. Eyer,et al.  Improved determination of acetylcholinesterase activity in human whole blood. , 1999, Clinica chimica acta; international journal of clinical chemistry.

[7]  P. Eyer,et al.  Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients , 1997, Human & experimental toxicology.

[8]  P. Eyer,et al.  Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning , 1997, Human & experimental toxicology.

[9]  R. Dawson,et al.  Review of oximes available for treatment of nerve agent poisoning , 1994, Journal of applied toxicology : JAT.

[10]  B. Ballantyne,et al.  Clinical and Experimental Toxicology of Organophosphates and Carbamates , 1992 .

[11]  W. K. Berry Some species differences in the rates of reaction of diaphragm particulate acetylcholinesterases with tetraethyl pyrophosphate and pralidoxime. , 1971, Biochemical pharmacology.

[12]  P. Eyer The Role of Oximes in the Management of Organophosphorus Pesticide Poisoning , 2003, Toxicological reviews.

[13]  B. Ballantyne,et al.  1 – Overview of the biological and clinical aspects of organophosphates and carbamates , 1992 .