Differential Modulation of Beta-Adrenergic Receptor Signaling by Trace Amine-Associated Receptor 1 Agonists
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T. Schöneberg | A. Grüters | H. Biebermann | H. Krude | J. Köhrle | D. Führer-Sakel | Juliane Pratzka | G. Kleinau | D. Nürnberg
[1] V. Trudeau,et al. β-blockers as endocrine disruptors: the potential effects of human β-blockers on aquatic organisms. , 2011, Journal of experimental zoology. Part A, Ecological genetics and physiology.
[2] T. Sotnikova,et al. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity , 2011, Proceedings of the National Academy of Sciences.
[3] Santiago Vilar,et al. In silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor. , 2011, Journal of molecular graphics & modelling.
[4] M. Hoener,et al. Selective antagonists of mouse trace amine-associated receptor 1 (mTAAR1): discovery of EPPTB (RO5212773). , 2011, Bioorganic & medicinal chemistry letters.
[5] Jörg D. Wichard,et al. Chemogenomic Analysis of G-Protein Coupled Receptors and Their Ligands Deciphers Locks and Keys Governing Diverse Aspects of Signalling , 2011, PloS one.
[6] J. Köhrle,et al. Thyronamines--past, present, and future. , 2011, Endocrine reviews.
[7] G. V. van Westen,et al. GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[8] Christopher G. Tate,et al. The structural basis for agonist and partial agonist action on a β1-adrenergic receptor , 2010, Nature.
[9] T. Schwartz,et al. The minor binding pocket: a major player in 7TM receptor activation. , 2010, Trends in pharmacological sciences.
[10] A. Serretti,et al. TAAR6 variations possibly associated with antidepressant response and suicidal behavior , 2010, Psychiatry Research.
[11] Jonathan A. Javitch,et al. Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist , 2010, Science.
[12] Cheng Zhang,et al. Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex , 2010, Nature.
[13] P. Vitti,et al. Tissue distribution and cardiac metabolism of 3-iodothyronamine. , 2010, Endocrinology.
[14] G. Aston-Jones,et al. 3-Monoiodothyronamine: The rationale for its action as an endogenous adrenergic-blocking neuromodulator , 2010, Brain Research.
[15] T. Scanlan,et al. 3-Iodothyronamine (T(1)AM): a new chapter of thyroid hormone endocrinology? , 2010, Molecular bioSystems.
[16] E. Vallender,et al. Normal thermoregulatory responses to 3‐iodothyronamine, trace amines and amphetamine‐like psychostimulants in trace amine associated receptor 1 knockout mice , 2010, Journal of neuroscience research.
[17] Wolfgang Enard,et al. Structural and Functional Evolution of the Trace Amine-Associated Receptors TAAR3, TAAR4 and TAAR5 in Primates , 2010, PloS one.
[18] I. Khan,et al. Effects of synephrine and beta-phenethylamine on human alpha-adrenoceptor subtypes. , 2010, Planta medica.
[19] G. Chiellini,et al. Cardiac effects of thyronamines , 2010, Heart Failure Reviews.
[20] S. Westmoreland,et al. Functional evolution of the trace amine associated receptors in mammals and the loss of TAAR1 in dogs , 2010, BMC Evolutionary Biology.
[21] G. Pizzolato,et al. Trace amine metabolism in Parkinson's disease: Low circulating levels of octopamine in early disease stages , 2010, Neuroscience Letters.
[22] M. Gassmann,et al. The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system , 2009, Proceedings of the National Academy of Sciences.
[23] A. Serretti,et al. TAAR 6 and HSP-70 variations associated with bipolar disorder , 2009, Neuroscience Letters.
[24] Liaoyuan A. Hu,et al. Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands. , 2009, The Biochemical journal.
[25] H. Navarro,et al. Amiodarone and its putative metabolites fail to activate wild type hTAAR1. , 2009, Bioorganic & medicinal chemistry letters.
[26] Catherine L. Worth,et al. Comparative Sequence and Structural Analyses of G-Protein-Coupled Receptor Crystal Structures and Implications for Molecular Models , 2009, PloS one.
[27] T. Sotnikova,et al. Trace Amine-Associated Receptors as Emerging Therapeutic Targets , 2009, Molecular Pharmacology.
[28] H. Breer,et al. Frontiers in Cellular Neuroscience Cellular Neuroscience Review Article Odorant Receptors (ors) Structural Features of Receptor Proteins , 2022 .
[29] S. Liberles,et al. Trace Amine‐associated Receptors Are Olfactory Receptors in Vertebrates , 2009, Annals of the New York Academy of Sciences.
[30] Eli S. Groban,et al. The molecular basis of species-specific ligand activation of trace amine-associated receptor 1 (TAAR(1)). , 2009, ACS chemical biology.
[31] S. Korsching,et al. Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts , 2009, Proceedings of the National Academy of Sciences.
[32] T. Scanlan. 3-Iodothyronamine (T1AM): A New Player on the Thyroid Endocrine Team? , 2009 .
[33] R. Neubig,et al. International Union of Pharmacology. LXXII. Recommendations for Trace Amine Receptor Nomenclature , 2009, Pharmacological Reviews.
[34] D. Grandy,et al. Modulation of cardiac ionic homeostasis by 3-iodothyronamine , 2009, Journal of cellular and molecular medicine.
[35] R. Stevens,et al. The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist , 2008, Science.
[36] T. Scanlan,et al. Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites. , 2008, Bioorganic & medicinal chemistry letters.
[37] J. Köhrle,et al. Development of a validated liquid chromatography/tandem mass spectrometry method for the distinction of thyronine and thyronamine constitutional isomers and for the identification of new deiodinase substrates. , 2008, Rapid communications in mass spectrometry : RCM.
[38] F. Ozoe,et al. Single amino acid of an octopamine receptor as a molecular switch for distinct G protein couplings. , 2008, Biochemical and biophysical research communications.
[39] Dietmar Krautwurst,et al. Human Olfactory Receptor Families and Their Odorants , 2008, Chemistry & biodiversity.
[40] S. Westmoreland,et al. Modulation of Monoamine Transporters by Common Biogenic Amines via Trace Amine-Associated Receptor 1 and Monoamine Autoreceptors in Human Embryonic Kidney 293 Cells and Brain Synaptosomes , 2008, Journal of Pharmacology and Experimental Therapeutics.
[41] Matthew P Jacobson,et al. Toward deciphering the code to aminergic G protein-coupled receptor drug design. , 2008, Chemistry & biology.
[42] J. Moreau,et al. Trace Amine-Associated Receptor 1 Modulates Dopaminergic Activity , 2008, Journal of Pharmacology and Experimental Therapeutics.
[43] D. Grandy,et al. Trace amine-associated receptor 1-Family archetype or iconoclast? , 2007, Pharmacology & therapeutics.
[44] R. Stevens,et al. High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor , 2007, Science.
[45] M. Burghammer,et al. Crystal structure of the human β2 adrenergic G-protein-coupled receptor , 2007, Nature.
[46] C. Swanson,et al. The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia , 2007, Genes, brain, and behavior.
[47] Y. Sawa,et al. Identification of critical structural determinants responsible for octopamine binding to the alpha-adrenergic-like Bombyx mori octopamine receptor. , 2007, Biochemistry.
[48] D. Grandy,et al. Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1. , 2007, Journal of medicinal chemistry.
[49] T. Scanlan,et al. Thyronamines are substrates for human liver sulfotransferases. , 2007, Endocrinology.
[50] S. Westmoreland,et al. Rhesus Monkey Trace Amine-Associated Receptor 1 Signaling: Enhancement by Monoamine Transporters and Attenuation by the D2 Autoreceptor in Vitro , 2007, Journal of Pharmacology and Experimental Therapeutics.
[51] G. Miller,et al. Trace Amine-Associated Receptor 1 Is a Modulator of the Dopamine Transporter , 2007, Journal of Pharmacology and Experimental Therapeutics.
[52] Y. Tu,et al. Pharmacologic Characterization of the Cloned Human Trace Amine-Associated Receptor1 (TAAR1) and Evidence for Species Differences with the Rat TAAR1 , 2007, Journal of Pharmacology and Experimental Therapeutics.
[53] G. Chiellini,et al. Trace amine‐associated receptors and their ligands , 2006, British journal of pharmacology.
[54] Linda B. Buck,et al. A second class of chemosensory receptors in the olfactory epithelium , 2006, Nature.
[55] T. Hicks,et al. The mysterious trace amines: Protean neuromodulators of synaptic transmission in mammalian brain , 2006, Progress in Neurobiology.
[56] Lewin Ah. Receptors of Mammalian Trace Amines , 2006 .
[57] D. Grandy,et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. , 2006, Journal of medicinal chemistry.
[58] C. Grimmelikhuijzen,et al. A new family of insect tyramine receptors. , 2005, Biochemical and biophysical research communications.
[59] M. Bly. Examination of the trace amine-associated receptor 2 (TAAR2) , 2005, Schizophrenia Research.
[60] Martin Ebeling,et al. An Automated System for the Analysis of G Protein-Coupled Receptor Transmembrane Binding Pockets: Alignment, Receptor-Based Pharmacophores, and Their Application , 2005, J. Chem. Inf. Model..
[61] Hong Yang,et al. Primate Trace Amine Receptor 1 Modulation by the Dopamine Transporter , 2005, Journal of Pharmacology and Experimental Therapeutics.
[62] Robert Fredriksson,et al. The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish. , 2005, Molecular phylogenetics and evolution.
[63] M. Hoener,et al. A renaissance in trace amines inspired by a novel GPCR family. , 2005, Trends in pharmacological sciences.
[64] Martin Ebeling,et al. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. , 2005, Genomics.
[65] Pablo V Gejman,et al. Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia. , 2004, American journal of human genetics.
[66] Mark D. Berry,et al. Mammalian central nervous system trace amines. Pharmacologic amphetamines, physiologic neuromodulators , 2004, Journal of neurochemistry.
[67] Darrell R. Abernethy,et al. International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels , 2003, Pharmacological Reviews.
[68] Enoch S. Huang,et al. Construction of a sequence motif characteristic of aminergic G protein–coupled receptors , 2003, Protein science : a publication of the Protein Society.
[69] T. Branchek,et al. Trace amine receptors as targets for novel therapeutics: legend, myth and fact. , 2003, Current opinion in pharmacology.
[70] D. Grandy,et al. Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor. , 2001, Molecular pharmacology.
[71] Beth Borowsky,et al. Trace amines: Identification of a family of mammalian G protein-coupled receptors , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[72] M. Berlan,et al. Selective activation of β3-adrenoceptors by octopamine: comparative studies in mammalian fat cells , 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.
[73] K. Carter,et al. Cloning of a putative human neurotransmitter receptor expressed in skeletal muscle and brain. , 1998, Biochemical and Biophysical Research Communications - BBRC.
[74] P. Evans,et al. Selective inhibition of adenylyl cyclase by octopamine via a human cloned α2A‐adrenoceptor , 1997 .
[75] R. Planta,et al. Molecular cloning and pharmacological characterization of a molluscan octopamine receptor. , 1997, Molecular pharmacology.
[76] J. Ramachandran,et al. Structure and Function of G Protein Coupled Receptors , 1990, Pharmaceutical Research.
[77] E. Borrelli,et al. Cloning and characterization of a Drosophila tyramine receptor. , 1990, The EMBO journal.
[78] J. Venter,et al. Cloning, localization, and permanent expression of a Drosophila octopamine receptor , 1990, Neuron.
[79] J. McGrath,et al. Activities of octopamine and synephrine stereoisomers on α‐adrenoceptors , 1988 .
[80] J. David,et al. Octopamine in invertebrates and vertebrates. A review , 1985, Progress in Neurobiology.
[81] R. Hesch,et al. Triiodothyronamine--a beta-adrenergic metabolite of triiodothyronine? , 1983, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[82] G. V. van Westen,et al. Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation. , 2011, Trends in pharmacological sciences.
[83] J. V. Wallach. Endogenous hallucinogens as ligands of the trace amine receptors: a possible role in sensory perception. , 2009, Medical hypotheses.
[84] A. Lewin. Receptors of mammalian trace amines , 2008, The AAPS Journal.
[85] Manfred Burghammer,et al. Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. , 2007, Nature.
[86] T. Roeder. Tyramine and octopamine: ruling behavior and metabolism. , 2005, Annual review of entomology.
[87] B. O'dowd,et al. Novel human G-protein-coupled receptors. , 2003, Biochemical and biophysical research communications.
[88] P. Seeman,et al. A serotonin-4 receptor-like pseudogene in humans. , 1998, Brain research. Molecular brain research.
[89] P. Evans,et al. Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor. , 1997, British journal of pharmacology.
[90] J. Ballesteros,et al. [19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors , 1995 .
[91] C. Brown,et al. Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors. , 1988, British journal of pharmacology.
[92] V. Cody,et al. Molecular structure and biochemical activity of 3,5,3'-triiodothyronamine. , 1984, Endocrine research.