Evaluation of cytotoxicity and immune modulatory activities of soyasaponin Ab: an in vitro and in vivo study.

[1]  H. Meng,et al.  Haemolytic activity and adjuvant effect of soyasaponins and some of their derivatives on the immune responses to ovalbumin in mice. , 2014, International immunopharmacology.

[2]  F. Gallyas,et al.  Antioxidant and Anti-Inflammatory Effects in RAW264.7 Macrophages of Malvidin, a Major Red Wine Polyphenol , 2013, PloS one.

[3]  Dayun Zhao,et al.  Efficient protocol for isolation and purification of different soyasaponins from soy hypocotyls. , 2012, Journal of separation science.

[4]  Dong-Hyun Kim,et al.  Soyasaponin Ab ameliorates colitis by inhibiting the binding of lipopolysaccharide (LPS) to Toll-like receptor (TLR)4 on macrophages. , 2011, Journal of agricultural and food chemistry.

[5]  A. Osbourn,et al.  The saponins: polar isoprenoids with important and diverse biological activities. , 2011, Natural product reports.

[6]  S. Akira,et al.  The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors , 2010, Nature Immunology.

[7]  Songhua Hu,et al.  Adjuvant activities of saponins from traditional Chinese medicinal herbs. , 2009, Vaccine.

[8]  Hongxiang Sun,et al.  Advances in saponin-based adjuvants. , 2009, Vaccine.

[9]  Jicheng Liu,et al.  Haemolytic activities and adjuvant effect of Anemone raddeana saponins (ARS) on the immune responses to ovalbumin in mice. , 2008, International immunopharmacology.

[10]  Wei Zhang,et al.  Effect of soyasapogenol A and soyasapogenol B concentrated extracts on HEP-G2 cell proliferation and apoptosis. , 2008, Journal of agricultural and food chemistry.

[11]  E. Merello,et al.  Hypoxia transcriptionally induces macrophage‐inflammatory protein‐3α/CCL‐20 in primary human mononuclear phagocytes through nuclear factor (NF)‐κB , 2008 .

[12]  Guo-Qing Huang,et al.  Soyasaponins inhibit the proliferation of Hela cells by inducing apoptosis. , 2007, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

[13]  H. Tanizawa,et al.  Effects of soyasaponins on lipid peroxidation through the secretion of thyroid hormones. , 2006, Biological & pharmaceutical bulletin.

[14]  Hongxiang Sun Adjuvant effect of Achyranthes bidentata saponins on specific antibody and cellular response to ovalbumin in mice. , 2006, Vaccine.

[15]  M. Inganäs,et al.  The Rb1 fraction of ginseng elicits a balanced Th1 and Th2 immune response. , 2005, Vaccine.

[16]  P. Murphy,et al.  Soyasaponins Lowered Plasma Cholesterol and Increased Fecal Bile Acids in Female Golden Syrian Hamsters , 2005, Experimental biology and medicine.

[17]  W. Verstraete,et al.  Simultaneous quantification of differently glycosylated, acetylated, and 2,3-dihydro-2,5-dihydroxy-6-methyl-4H-pyran-4-one-conjugated soyasaponins using reversed-phase high-performance liquid chromatography with evaporative light scattering detection. , 2005, Journal of chromatography. A.

[18]  W. Reynolds,et al.  The isolation of soyasaponins by fractional precipitation, solid phase extraction, and low pressure liquid chromatography , 2005, International journal of food sciences and nutrition.

[19]  T. Nohara,et al.  Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells. , 2003, Biological & pharmaceutical bulletin.

[20]  H. Matsuda,et al.  Relationship between adjuvant activity and amphipathic structure of soyasaponins. , 2003, Vaccine.

[21]  T. Nagamine,et al.  Onjisaponins, from the root of Polygala tenuifolia Willdenow, as effective adjuvants for nasal influenza and diphtheria-pertussis-tetanus vaccines. , 2001, Vaccine.

[22]  S. Vaughn,et al.  Characterization and antimutagenic activity of soybean saponins. , 2000, Mutation research.

[23]  H. Matsuda,et al.  Adjuvant and Haemolytic Activities of 47 Saponins Derived from Medicinal and Food Plants , 2000, Biological chemistry.

[24]  T. Nohara,et al.  Structure-Hepatoprotective Relationships Study of Soyasaponins I-IV Having Soyasapogenol B as Aglycone# , 1998, Planta medica.

[25]  H. Hayashi,et al.  Inhibitory Activity of Soyasaponin II on Virus Replication in vitro , 1997, Planta medica.

[26]  J. Cox,et al.  Adjuvants--a classification and review of their modes of action. , 1997, Vaccine.

[27]  K. Harada,et al.  Composition and structure of "group B saponin" in soybean seed. , 1991, Agricultural and biological chemistry.

[28]  N. Yamamoto,et al.  Inhibitory effect of glycosides like saponin from soybean on the infectivity of HIV in vitro. , 1989, AIDS.

[29]  I. Kitagawa,et al.  Saponin and sapogenol. XXXVIII. Structure of soyasaponin A2, a bisdesmoside of soyasapogenol A, from soybean, the seeds of Glycine max Merrill. , 1985 .

[30]  T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.

[31]  I. Yosioka,et al.  Saponin and Sapogenol. XIII. Structures of Three Soybean Saponins : Soyasaponin I, Soyasaponin II, and Soyasaponin III , 1976 .

[32]  Mi-Kyung Sung,et al.  Protective effect of soybean saponins and major antioxidants against aflatoxin B1-induced mutagenicity and DNA-adduct formation. , 2002, Journal of medicinal food.

[33]  R. Bomford,et al.  Adjuvanticity and ISCOM formation by structurally diverse saponins. , 1992, Vaccine.

[34]  G. S. Sidhu,et al.  Could saponins be a useful treatment for hypercholesterolaemia? , 1990, European journal of clinical nutrition.