Epidemiology of Kawasaki Disease in Asia, Europe, and the United States

Kawasaki disease (KD) is a systemic vasculitis that mainly affects children younger than 5 years. Although Dr. Tomisaku Kawasaki first reported KD over 40 years ago, the cause of the disease remains unknown. Currently, KD has been diagnosed in more than 60 countries, including those in Asia, the Middle East, Latin America, and Africa, as well as in North America and Europe. The purpose of this review is to describe the epidemiologic features of KD—particularly its incidence, seasonality, and the occurrence of coronary artery abnormalities—primarily in Japan and the United States, but also in Europe and other Asian countries.

[1]  R. Sung,et al.  Kawasaki disease in Hong Kong, 1994 to 2000. , 2005, Hong Kong medical journal = Xianggang yi xue za zhi.

[2]  E. Salo.  Kawasaki disease in Finland in 1982-1992. , 1993, Scandinavian journal of infectious diseases.

[3]  Yoshikazu Nakamura,et al.  Revision of diagnostic guidelines for Kawasaki disease (the 5th revised edition) , 2005, Pediatrics international : official journal of the Japan Pediatric Society.

[4]  K. Kotani,et al.  Epidemiologic Features of Kawasaki Disease in Japan: Results of the 2007–2008 Nationwide Survey , 2010, Journal of epidemiology.

[5]  A. Sheikh,et al.  Rising incidence of Kawasaki disease in England: analysis of hospital admission data , 2002, BMJ : British Medical Journal.

[6]  Hack‐Ki Kim,et al.  Kawasaki disease in Korea , 1992 .

[7]  P. Pelkonen,et al.  Outbreak of Kawasaki Syndrome in Finland , 1986, Acta paediatrica Scandinavica.

[8]  R. Holman,et al.  Kawasaki syndrome hospitalizations among children in the United States, 1988-1997. , 2003, Pediatrics.

[9]  M. Goldacre,et al.  Kawasaki Disease in England: Ethnicity, Deprivation, and Respiratory Pathogens , 2009, The Pediatric infectious disease journal.

[10]  Xiaojing Ma,et al.  Epidemiologic Pictures of Kawasaki disease in Shanghai from 1998 through 2002 , 2005, Journal of epidemiology.

[11]  R. Sittiwangkul,et al.  Epidemiologic study of Kawasaki disease and cases resistant to IVIG therapy in Thailand. , 2006, Asian Pacific journal of allergy and immunology.

[12]  Junbao Du,et al.  VALGANCICLOVIR FOR CONGENITAL CMV INFECTION: A PILOT STUDY ON PLASMA CONCENTRATION IN NEWBORNS AND INFANTS , 2007, The Pediatric infectious disease journal.

[13]  K. Nishigaki,et al.  Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease (JCS 2008)--digest version. , 2010, Circulation journal : official journal of the Japanese Circulation Society.

[14]  I. Park,et al.  Kawasaki Disease in Korea, 2003–2005 , 2007, The Pediatric infectious disease journal.

[15]  R. Cimaz,et al.  Kawasaki's disease in northern Italy: a multicenter retrospective study of 250 patients. , 2002, Clinical and experimental rheumatology.

[16]  R. Holman,et al.  Racial/ethnic differences in the incidence of Kawasaki syndrome among children in Hawaii. , 2010, Hawaii medical journal.

[17]  R. Uehara,et al.  Kawasaki Disease in Mongolia: Results From 2 Nationwide Retrospective Surveys, 1996–2008 , 2011, Journal of epidemiology.

[18]  R. Holman,et al.  Analysis of Potential Risk Factors Associated With Nonresponse to Initial Intravenous Immunoglobulin Treatment Among Kawasaki Disease Patients in Japan , 2008, The Pediatric infectious disease journal.

[19]  J. Burns,et al.  The two emergencies of Kawasaki syndrome and the implications for the developing world. , 2008, The Pediatric infectious disease journal.

[20]  M. Melish,et al.  Mucocutaneous lymph node syndrome in the United States. , 1976, American journal of diseases of children.

[21]  R. Holman,et al.  Kawasaki Syndrome in Denmark , 2007, The Pediatric infectious disease journal.

[22]  A. Fasth,et al.  Kawasaki disease in Sweden: incidence and clinical features , 1995, Acta paediatrica.

[23]  R. Holman,et al.  Kawasaki syndrome hospitalizations in Ireland, 1996 through 2000 , 2003, The Pediatric infectious disease journal.

[24]  R. Holman,et al.  Hospitalizations for Kawasaki Syndrome Among Children in the United States, 1997–2007 , 2010, The Pediatric infectious disease journal.

[25]  G. Tamburlini,et al.  A two-year survey of mucocutaneous lymph node syndrome in northeastern Italy. Epidemiological and clinical findings. , 1984, Helvetica paediatrica acta.

[26]  R. Uehara,et al.  Case‐control study of giant coronary aneurysms due to Kawasaki disease , 2003, Pediatrics international : official journal of the Japan Pediatric Society.

[27]  柳川 洋.  Epidemiology of Kawasaki disease : A 30‐year achievement , 2004 .

[28]  R. Uehara,et al.  Case–control study of giant coronary aneurysms due to Kawasaki disease: The 19th nationwide survey , 2010, Pediatrics international : official journal of the Japan Pediatric Society.

[29]  Pei-Jer Chen,et al.  Epidemiologic Features of Kawasaki Disease in Taiwan, 2003–2006 , 2009, Pediatrics.

[30]  Walter R Wilson,et al.  Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association , 2004, Circulation.

[31]  H. Yanagawa,et al.  The worldwide epidemiology of Kawasaki disease , 2004 .

[32]  Y. T. Lin,et al.  Repeated systematic surveillance of Kawasaki disease in Ontario from 1995 to 2006 , 2010, Pediatrics international : official journal of the Japan Pediatric Society.

[33]  R. Holman,et al.  Kawasaki Syndrome and Risk Factors for Coronary Artery Abnormalities: United States, 1994–2003 , 2006, The Pediatric infectious disease journal.

[34]  Min Huang,et al.  Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017 , 2019, Case Medical Research.

[35]  S. Colan,et al.  Coronary artery dimensions may be misclassified as normal in Kawasaki disease. , 1998, The Journal of pediatrics.

[36]  Sang Bum Lee,et al.  Epidemiological features of Kawasaki disease in Korea, 2006–2008 , 2011, Pediatrics international : official journal of the Japan Pediatric Society.

[37]  J. Burns,et al.  Is Kawasaki disease incidence rising in Chandigarh, North India? , 2010, Archives of Disease in Childhood.

[38]  A. Martinot,et al.  Increased detection rate of Kawasaki disease using new diagnostic algorithm, including early use of echocardiography. , 2009, The Journal of pediatrics.

[39]  K. Kotani,et al.  Epidemiologic Features of Kawasaki Disease in Japan: Results of the 2009–2010 Nationwide Survey , 2012, Journal of epidemiology.

[40]  K. Shibuya,et al.  Kawasaki disease before kawasaki at Tokyo university hospital. , 2002, Pediatrics.

[41]  Chin‐Yun Lee,et al.  Epidemiologic Features of Kawasaki Disease in Taiwan, 1996–2002 , 2004, Pediatrics.