Retinopretectal and accessory optic projections of normal mice and the OKN‐defective mutant mice beige, beige‐J, and pearl

Retinal projections to the pretectal and terminal accessory optic nuclei were studied in normal wild‐type mice and mutant mice with abnormal optokinetic nystagmus (OKN, Mangini, Vanable, Williams, and Pinto: J. Comp. Neurol. 247:191–209, '85). The mutants used were (1) pearl, which exhibits an inverted OKN in response to stimulation of only the temporal retina, and (2) beige and beige‐J, which show inverted OKN in response to stimulation of only the temporal retina and, in addition, exhibit eye movements with a vertical component in response to horizontally moving, full‐field stimuli. These projections were studied following intraocular injections of 3H‐proline or horseradish peroxidase (HRP) with, respectively, light microscopic auto‐radiography or HRP histochemistry.

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