Making the step from chemistry to biology and back.

There is a gap between the nanoscale level of molecular structure and the micron-sized level of cellular ultrastructure that is difficult to probe experimentally. New techniques and simulated images are revealing its secrets.

[1]  J. Ottino.  Is a picture worth 1,000 words? , 2003, Nature.

[2]  D. Klionsky,et al.  Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast , 2006, The Journal of cell biology.

[3]  David S. Goodsell.  The machinery of life , 1993 .

[4]  David S Goodsell.  Looking at Molecules—An Essay on Art and Science , 2003, Chembiochem : a European journal of chemical biology.

[5]  J. Richardson,et al.  The anatomy and taxonomy of protein structure. , 1981, Advances in protein chemistry.

[6]  David S Goodsell,et al.  Visual methods from atoms to cells. , 2005, Structure.

[7]  D S Goodsell,et al.  Inside a living cell. , 1991, Trends in biochemical sciences.

[8]  Helmut Grubmüller,et al.  Molecular Anatomy of a Trafficking Organelle , 2006, Cell.

[9]  Brad J Marsh,et al.  Lessons from tomographic studies of the mammalian Golgi. , 2005, Biochimica et biophysica acta.

[10]  Joachim Frank,et al.  Three-dimensional imaging of biological complexity. , 2002, Journal of structural biology.