Magnetic resonance imaging, pacemakers and implantable cardioverter-defibrillators: current situation and clinical perspective.

New developments and expanding indications have resulted in a significant increase in the number of patients with pacemakers and internal cardioverterdefibrillators (ICDs). Because of its unique capabilities, magnetic resonance imaging (MRI) has become one of the most important imaging modalities for evaluation of the central nervous system, tumours, musculoskeletal disorders and some cardiovascular diseases. As a consequence of these developments, an increasing number of patients with implanted devices meet the standard indications for MRI examination. Due to the presence of potential life-threatening risks and interactions, however, pacemakers and ICDs are currently not approved by the Food and Drug Administration (FDA) for use in an MRI scanner. Despite these limitations and restrictions, a limited but still growing number of studies reporting on the effects and safety issues of MRI and implanted devices have been published. Because physicians will be increasingly confronted with the issue of MRI in patients with implanted devices, this overview is given. The effects of MRI on an implanted pacemaker and/or ICDs and vice versa are described and, based on the current literature, a strategy for safe performance of MRI in these patients is proposed. (Neth Heart J 2010;18:31-7.).

[1]  C. Walton,et al.  Platinum Pacemaker Electrodes: Origins and Effects of the Electrode‐Tissue Interface Impedance , 1987, Pacing and clinical electrophysiology : PACE.

[2]  Stephen J Riederer,et al.  MR imaging: its development and the recent Nobel Prize. , 2004, Radiology.

[3]  C. Meyer,et al.  MRT-Untersuchungen des Hirns bei Patienten mit implantierten Herzschrittmachern. Experimentelle und klinische Untersuchungen an einem 1,5 Tesla-System , 2005 .

[4]  J Gieseke,et al.  MR imaging and cardiac pacemakers: in-vitro evaluation and in-vivo studies in 51 patients at 0.5 T. , 2000, Radiology.

[5]  Z. Fayad The assessment of the vulnerable atherosclerotic plaque using MR imaging: A brief review , 2001, The International Journal of Cardiovascular Imaging.

[6]  Emanuel Kanal,et al.  Outcome of Magnetic Resonance Imaging (MRI) in Selected Patients with Implantable Cardioverter Defibrillators (ICDs) , 2005, Pacing and clinical electrophysiology : PACE.

[7]  D. Pennell,et al.  Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. , 2002, The American journal of cardiology.

[8]  Henry R. Halperin,et al.  Modern Pacemaker and Implantable Cardioverter/Defibrillator Systems Can Be Magnetic Resonance Imaging Safe: In Vitro and In Vivo Assessment of Safety and Function at 1.5 T , 2004, Circulation.

[9]  J. Zwanenburg,et al.  Propagation of onset and peak time of myocardial shortening in time of myocardial shortening in ischemic versus nonischemic cardiomyopathy: assessment by magnetic resonance imaging myocardial tagging. , 2005, Journal of the American College of Cardiology.

[10]  M Gent,et al.  Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes , 2000 .

[11]  P Boesiger,et al.  Force and Torque Effects of a 1.5‐Tesla MRI Scanner on Cardiac Pacemakers and ICDs , 2001, Pacing and clinical electrophysiology : PACE.

[12]  D. DeMets,et al.  Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. , 2004, The New England journal of medicine.

[13]  Peter Boesiger,et al.  In vivo heating of pacemaker leads during magnetic resonance imaging. , 2005, European heart journal.

[14]  Harold Litt,et al.  Strategy for Safe Performance of Extrathoracic Magnetic Resonance Imaging at 1.5 Tesla in the Presence of Cardiac Pacemakers in Non–Pacemaker-Dependent Patients: A Prospective Study With 115 Examinations , 2006, Circulation.

[15]  O. Simonetti,et al.  The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. , 2000, The New England journal of medicine.

[16]  James C Moon,et al.  Interstudy reproducibility of right ventricular volumes, function, and mass with cardiovascular magnetic resonance. , 2004, American heart journal.

[17]  Ron Kalin,et al.  Current Clinical Issues for MRI Scanning of Pacemaker and Defibrillator Patients , 2005, Pacing and clinical electrophysiology : PACE.

[18]  E. Kanal,et al.  Safety of magnetic resonance imaging of patients with a new Medtronic EnRhythm MRI SureScan pacing system: clinical study design , 2008, Trials.

[19]  A. van Rossum,et al.  Clinical applications of cardiovascular magnetic resonance imaging , 2006, Canadian Medical Association Journal.

[20]  T. Gross,et al.  The epidemiology of pacemaker implantation in the United States. , 1995, Public health reports.

[21]  H. Halperin,et al.  Clinical Utility and Safety of a Protocol for Noncardiac and Cardiac Magnetic Resonance Imaging of Patients With Permanent Pacemakers and Implantable-Cardioverter Defibrillators at 1.5 Tesla , 2006, Circulation.

[22]  W. Stevenson,et al.  Recalls and safety alerts involving pacemakers and implantable cardioverter-defibrillator generators. , 2001, JAMA.

[23]  Robert Fair,et al.  Magnetic resonance imaging and cardiac pacemaker safety at 1.5-Tesla. , 2004, Journal of the American College of Cardiology.

[24]  P. Tchou,et al.  Strategies for the Safe Magnetic Resonance Imaging of Pacemaker‐Dependent Patients , 2005, Pacing and clinical electrophysiology : PACE.

[25]  S. Priori,et al.  Magnetic resonance imaging in individuals with cardiovascular implantable electronic devices. , 2008, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[26]  Wilson Greatbatch,et al.  Magnetic resonance safety testing of a newly‐developed fiber‐optic cardiac pacing lead , 2002, Journal of magnetic resonance imaging : JMRI.

[27]  L. Goldman,et al.  Quality of life and clinical outcomes in elderly patients treated with ventricular pacing as compared with dual-chamber pacing. , 1998, Pacing and clinical electrophysiology : PACE.