COMPARATIVE STUDIES OF THE EFFECTS OF α-TOCOPHERYL NICOTINATE AND THE COMBINATION α-TOCOPHERYL ACETATE AND NICOTINIC ACID

By conducting a cross administration of Toc. nic and the combination of Toc. ace and 20% nicotinic acid to cases with insufficient micro-circulation and also by performing the cooling rewarming test during the administration, it was found that Toc. nic is more effective than the combination in reducing the MRT, and that the effectiveness of Toc. nic was not due to the synergic action of tocopherol and nicotinic acid but to the independent action of Toc. nic.