Norepinephrine inhibits CD8+ T-cell infiltration and function, inducing anti-PD-1 mAb resistance in lung adenocarcinoma

[1]  D. Bernabé.  Catecholamines Mediate Psychologic Stress–Induced Cancer Progression , 2021, Cancer Research.

[2]  D. Sarkar,et al.  Beta 2 Adrenergic Receptor Antagonist Propranolol and Opioidergic Receptor Antagonist Naltrexone Produce Synergistic Effects on Breast Cancer Growth Prevention by Acting on Cancer Cells and Immune Environment in a Preclinical Model of Breast Cancer , 2021, Cancers.

[3]  W. Xue,et al.  Transcriptome Sequencing and Metabolome Analysis Reveal the Mechanism of Shuanghua Baihe Tablet in Treatment of Oral Mucositis , 2021 .

[4]  Li-feng Li,et al.  COL1A1 is a prognostic biomarker and correlated with immune infiltrates in lung cancer , 2021, PeerJ.

[5]  Dexin Kong,et al.  Chronic restraint stress promotes the mobilization and recruitment of myeloid‐derived suppressor cells through β‐adrenergic‐activated CXCL5‐CXCR2‐Erk signaling cascades , 2021, International journal of cancer.

[6]  Min Su,et al.  The cancer metabolic reprogramming and immune response , 2021, Molecular cancer.

[7]  L. Jia,et al.  M2‐like tumor‐associated macrophages‐secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating β‐catenin pathway in thyroid cancer , 2020, Molecular carcinogenesis.

[8]  D. Fliser,et al.  WNT–β-catenin signalling — a versatile player in kidney injury and repair , 2020, Nature Reviews Nephrology.

[9]  D. Jackson,et al.  Chronic stress physically spares but functionally impairs innate-like invariant T cells , 2020, Cell reports.

[10]  J. Bai,et al.  Microbiome-gut-brain axis in cancer treatment-related psychoneurological toxicities and symptoms: a systematic review , 2020, Supportive Care in Cancer.

[11]  A. Shanker,et al.  Critical Neurotransmitters in the Neuroimmune Network , 2020, Frontiers in Immunology.

[12]  Z. Zeng,et al.  Chronic Stress Promotes Cancer Development , 2020, Frontiers in Oncology.

[13]  K. Sun,et al.  Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors , 2020, Frontiers in Cell and Developmental Biology.

[14]  L. Buisseret,et al.  Publisher Correction: The adenosine pathway in immuno-oncology , 2020, Nature Reviews Clinical Oncology.

[15]  H. McLeod,et al.  Propranolol suppresses the growth of colorectal cancer through simultaneously activating autologous CD8+ T cells and inhibiting tumor AKT/MAPK pathway. , 2020, Clinical pharmacology and therapeutics.

[16]  Z. Cooper,et al.  Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade , 2020, Journal for immunotherapy of cancer.

[17]  D. Gao,et al.  Norepinephrine-stimulated HSCs secrete sFRP1 to promote HCC progression following chronic stress via augmentation of a Wnt16B/β-catenin positive feedback loop , 2020, Journal of Experimental & Clinical Cancer Research.

[18]  P. Frenette,et al.  Nerves in cancer , 2020, Nature Reviews Cancer.

[19]  E. Martín-Orozco,et al.  WNT Signaling in Tumors: The Way to Evade Drugs and Immunity , 2019, Frontiers in Immunology.

[20]  Jason D. Buenrostro,et al.  Hyperactivation of Sympathetic Nerves Drives Melanocyte Stem Cell Depletion , 2019, Nature.

[21]  B. Hylander,et al.  β2 Adrenergic receptor-mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells. , 2019, The Journal of clinical investigation.

[22]  Zekuan Xu,et al.  Chronic stress promotes gastric cancer progression and metastasis: an essential role for ADRB2 , 2019, Cell Death & Disease.

[23]  Zhi-gang Zhang,et al.  Neurotransmitters: emerging targets in cancer , 2019, Oncogene.

[24]  L. Lanfumey,et al.  Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity , 2019, Nature Medicine.

[25]  Y. Yanagawa,et al.  Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression , 2019, Nature Neuroscience.

[26]  D. Jackson,et al.  Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. , 2019, Cancer cell.

[27]  F. Dhabhar,et al.  The impact of psychosocial stress and stress management on immune responses in patients with cancer , 2019, Cancer.

[28]  E. Fuchs,et al.  WNT Signaling in Cancer Immunosurveillance. , 2019, Trends in cell biology.

[29]  L. Emens,et al.  Targeting adenosine for cancer immunotherapy , 2018, Journal of Immunotherapy for Cancer.

[30]  M. Hung,et al.  STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion , 2018, Nature Communications.

[31]  Benjamin J. Raphael,et al.  Abstract PR03: Genetic mechanisms of immune evasion in colorectal cancer , 2018, Systems Immuno-Oncology.

[32]  B. Hylander,et al.  Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response , 2018, Front. Immunol..

[33]  J. Werner,et al.  β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer. , 2018, Cancer cell.

[34]  Edward S. Kim,et al.  Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers , 2017, Science Translational Medicine.

[35]  B. Hylander,et al.  β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy. , 2017, Cancer research.

[36]  M. Groettrup,et al.  Chronic stress suppresses anti-tumor TCD8+ responses and tumor regression following cancer immunotherapy in a mouse model of melanoma , 2017, Brain, Behavior, and Immunity.

[37]  R. Nusse,et al.  Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities , 2017, Cell.

[38]  Robert Ford,et al.  iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics. , 2017, The Lancet. Oncology.

[39]  K. Czene,et al.  Clinical Diagnosis of Mental Disorders Immediately Before and After Cancer Diagnosis: A Nationwide Matched Cohort Study in Sweden. , 2016, JAMA oncology.

[40]  Ping Hu,et al.  β2-adrenergic receptor activation promotes the proliferation of A549 lung cancer cells via the ERK1/2/CREB pathway. , 2016, Oncology reports.

[41]  G. Page,et al.  Stress impairs the efficacy of immune stimulation by CpG-C: Potential neuroendocrine mediating mechanisms and significance to tumor metastasis and the perioperative period , 2016, Brain, Behavior, and Immunity.

[42]  S. Ryu,et al.  Molecular Mechanisms Underlying Psychological Stress and Cancer. , 2016, Current pharmaceutical design.

[43]  Yanfei Li,et al.  The immunotoxicity of aluminum trichloride on rat peritoneal macrophages via β2-adrenoceptors/cAMP pathway acted by norepinephrine. , 2016, Chemosphere.

[44]  D. Ferrari,et al.  Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination , 2016, Nature Communications.

[45]  A. Azmi,et al.  Immune evasion in cancer: Mechanistic basis and therapeutic strategies. , 2015, Seminars in cancer biology.

[46]  T. Gajewski,et al.  Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity , 2015, Nature.

[47]  F. Dhabhar,et al.  High-Anxious Individuals Show Increased Chronic Stress Burden, Decreased Protective Immunity, and Increased Cancer Progression in a Mouse Model of Squamous Cell Carcinoma , 2012, PloS one.

[48]  R. Gainetdinov,et al.  The Physiology, Signaling, and Pharmacology of Dopamine Receptors , 2011, Pharmacological Reviews.

[49]  C. Mongini,et al.  Chronic restraint stress impairs T-cell immunity and promotes tumor progression in mice , 2009, Stress.

[50]  E. Sternberg,et al.  Neuroendocrine regulation of immunity. , 2003, Annual review of immunology.

[51]  E. Wilder,et al.  Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells. , 2002, Cancer research.