NABTT 0502: a phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme.
暂无分享,去创建一个
Spain | T. Mikkelsen | M. Ahluwalia | S. Phuphanich | M. Rosenfeld | J. Supko | S. Grossman | L. Nabors | X. Ye | D. Peereboom | S. Kimmel | S. Hilderbrand | Cleveland Clinic | Maryland | Massachusetts Boston | Cleveland | S. Massachusetts | General Hospital | L. Barcelona | Henry Ford Hospital
[1] S. Phuphanich,et al. Phase I trial of sorafenib in patients with recurrent or progressive malignant glioma. , 2011, Neuro-oncology.
[2] Uwe Fuhr,et al. Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors , 2011, Clinical pharmacokinetics.
[3] Sagar Agarwal,et al. The Role of the Breast Cancer Resistance Protein (ABCG2) in the Distribution of Sorafenib to the Brain , 2011, Journal of Pharmacology and Experimental Therapeutics.
[4] J. Beijnen,et al. Erlotinib and pantoprazole: a relevant interaction or not? , 2010, British journal of clinical pharmacology.
[5] R. McLendon,et al. Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma. , 2010, Neuro-oncology.
[6] E. Giovannetti,et al. A Multicenter Phase II Study of Erlotinib and Sorafenib in Chemotherapy-Naïve Patients with Advanced Non–Small Cell Lung Cancer , 2010, Clinical Cancer Research.
[7] L. Chin,et al. Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence , 2010, Proceedings of the National Academy of Sciences.
[8] J. Uhm. Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group , 2010 .
[9] W. Kaelin,et al. Erlotinib therapy for central nervous system hemangioblastomatosis associated with von Hippel-Lindau disease: a case report , 2010, Journal of Neuro-Oncology.
[10] Susan M. Chang,et al. A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy. , 2010, Neuro-oncology.
[11] Susan M. Chang,et al. A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas. , 2010, Neuro-oncology.
[12] M. Prados,et al. Phase I/II study of sorafenib and temsirolimus for patients with recurrent glioblastoma (GBM) (NABTC 05-02). , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] M. J. van den Bent,et al. Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] M. Prados,et al. Phase I/II study of sorefenib and erlotinib for patients with recurrent glioblastoma (GBM) (NABTC 05-02). , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[15] C. Rudin,et al. Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] Keith L. Ligon,et al. Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies , 2007, Science.
[17] G. Pond,et al. Phase I Targeted Combination Trial of Sorafenib and Erlotinib in Patients with Advanced Solid Tumors , 2007, Clinical Cancer Research.
[18] Forest M White,et al. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma , 2007, Proceedings of the National Academy of Sciences.
[19] Sumithra J. Mandrekar,et al. Phase I Trial of Sorafenib in Combination with Gefitinib in Patients with Refractory or Recurrent Non–Small Cell Lung Cancer , 2007, Clinical Cancer Research.
[20] M. Hidalgo,et al. Assessment of erlotinib pharmacodynamics in tumors and skin of patients with head and neck cancer. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.
[21] B. Lum,et al. The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition , 2007, European Journal of Clinical Pharmacology.
[22] R. Pazdur,et al. Sorafenib for the Treatment of Advanced Renal Cell Carcinoma , 2006, Clinical Cancer Research.
[23] R. Bruno,et al. Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer , 2006, Clinical pharmacology and therapeutics.
[24] J. Raizer,et al. Erratum: Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: Tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01 (Clinical Cancer Research (November 1, 2005) 11 (7841-7850)) , 2006 .
[25] Susan Chang,et al. Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. , 2006, Neuro-oncology.
[26] Koji Yoshimoto,et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. , 2005, The New England journal of medicine.
[27] Susan M. Chang,et al. Molecular Study of Malignant Gliomas Treated with Epidermal Growth Factor Receptor Inhibitors: Tissue Analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01 , 2005, Clinical Cancer Research.
[28] A. Oza,et al. Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors. , 2005, Annals of oncology : official journal of the European Society for Medical Oncology.
[29] Jeffrey W. Clark,et al. Safety and Pharmacokinetics of the Dual Action Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor, BAY 43-9006, in Patients with Advanced, Refractory Solid Tumors , 2005, Clinical Cancer Research.
[30] M. Piccart,et al. Phase I safety and pharmacokinetics of BAY 43-9006 administered for 21 days on/7 days off in patients with advanced, refractory solid tumours , 2005, British Journal of Cancer.
[31] Martin J. van den Bent,et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. , 2005, The New England journal of medicine.
[32] Dirk Strumberg,et al. Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] J. Holmlund,et al. Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-alpha delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas. , 2005, Neuro-oncology.
[34] L. Ellis,et al. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.
[35] S. Steinberg,et al. Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[36] G. Barnett,et al. Phase II trial of the EGFR tyrosine kinase inhibitor erlotinib for single agent therapy of recurrent Glioblastoma Multiforme: Interim results. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[37] W. Yung,et al. The autocrine loop of TGF-α/EGFR and brain tumors , 1997, Journal of Neuro-Oncology.
[38] X Yu,et al. J.Chromatogr., B: Anal. Technol. Biomed. Life Sci. , 2004 .
[39] T. Mikkelsen,et al. Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11. , 2004, Neuro-oncology.
[40] M. Hidalgo,et al. Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography-tandem mass spectrometry. , 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[41] T. Efferth,et al. EGFR but not PDGFR-beta expression correlates to the antiproliferative effect of growth factor withdrawal in glioblastoma multiforme cell lines. , 2003, Anticancer research.
[42] M. Hidalgo,et al. Development of the epidermal growth factor receptor inhibitor Tarceva (OSI-774). , 2003, Advances in experimental medicine and biology.
[43] Arnab Chakravarti,et al. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. , 2002, Cancer research.
[44] L. Grochow,et al. Toxicity, efficacy, and pharmacology of suramin in adults with recurrent high-grade gliomas. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[45] E K Rowinsky,et al. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[46] D. Gutmann,et al. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas. , 2001, Cancer research.
[47] A. Pawson,et al. Proliferation of human malignant astrocytomas is dependent on Ras activation , 1997, Oncogene.
[48] A Bye,et al. Common noncompartmental pharmacokinetic variables: are they normally or log-normally distributed? , 1997, Journal of biopharmaceutical statistics.
[49] W. Yung,et al. The autocrine loop of TGF-alpha/EGFR and brain tumors. , 1997, Journal of neuro-oncology.
[50] M Kiessling,et al. Amplification of the epidermal‐growth‐factor‐receptor gene correlates with different growth behaviour in human glioblastoma , 2007, International journal of cancer.
[51] O D Laerum,et al. Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. , 1990, Cancer research.
[52] T. Cascino,et al. Response criteria for phase II studies of supratentorial malignant glioma. , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[53] E. Mizuta,et al. Preparation of mean drug concentration--time curves in plasma. A study on the frequency distribution of pharmacokinetic parameters. , 1985, Chemical & pharmaceutical bulletin.
[54] P. Echlin,et al. Amplification and overexpression of the EGF receptor gene in primary human glioblastomas , 1985 .
[55] P. Echlin,et al. Amplification and Overexpression of the EGF Receptor Gene in Primary Human Glioblastomas , 1985, Journal of Cell Science.
[56] Hermona Soreq,et al. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin , 1985, Nature.
[57] Rupert G. Miller. The jackknife-a review , 1974 .