Coverage and throughput analysis for FRET-based mobile molecular sensor/actor nanonetworks

Abstract Nanonetworks are envisaged to expand the capabilities of single nanomachines by enabling collaboration through communication between them. Forster Resonance Energy Transfer (FRET) observed among fluorescent molecules is a promising means of high-rate and reliable information transfer between single fluorophore-based nanoscale molecular machines. Recent theoretical studies have underlined its practicality for mobile ad hoc nanonetworks consisting of functionalized fluorescent molecules. In this study, we focus on the spatial characteristics of FRET-Based Mobile Molecular Sensor/Actor Nanonetworks (FRET-MSAN) by investigating the network performance in terms of communication coverage, network throughput and information propagation rate through extensive Monte Carlo simulations. The effect of fundamental system parameters related to FRET and to the mobility of the network nodes on the network performance is revealed. The results of the simulations indicate that the throughput and propagation rate as a function of distance from the information source are well-fitted by exponential curves. We also observe that the impact of FRET mechanism suppresses the effect of Brownian motion of network nodes on the exciton mobility.

[1]  J. Lakowicz Principles of fluorescence spectroscopy , 1983 .

[2]  T. Suda,et al.  Molecular communication for nanomachines using intercellular calcium signaling , 2005, 5th IEEE Conference on Nanotechnology, 2005..

[3]  T. Jovin,et al.  FRET imaging , 2003, Nature Biotechnology.

[4]  Ian F. Akyildiz,et al.  Electromagnetic wireless nanosensor networks , 2010, Nano Commun. Networks.

[5]  Murat Kuscu,et al.  Multi-Step FRET-Based Long-Range Nanoscale Communication Channel , 2013, IEEE Journal on Selected Areas in Communications.

[6]  L. Breuer Introduction to Stochastic Processes , 2022, Statistical Methods for Climate Scientists.

[7]  Xiaobo Chen,et al.  Semiconductor quantum dots for photodynamic therapy. , 2003, Journal of the American Chemical Society.

[8]  Murat Kuscu,et al.  A Physical Channel Model and Analysis for Nanoscale Molecular Communications With Förster Resonance Energy Transfer (FRET) , 2012, IEEE Transactions on Nanotechnology.

[9]  A. P. de Silva,et al.  The development of molecular fluorescent switches. , 2001, Trends in biotechnology.

[10]  Th. Förster Zwischenmolekulare Energiewanderung und Fluoreszenz , 1948 .

[11]  Joseph R. Lakowicz,et al.  Principles of Fluorescence Spectroscopy, Third Edition , 2008 .

[12]  Murat Kuscu,et al.  FRET-based mobile molecular nanonetworks , 2013, 2013 12th Annual Mediterranean Ad Hoc Networking Workshop (MED-HOC-NET).

[13]  Ian F. Akyildiz,et al.  Nanonetworks: A new communication paradigm , 2008, Comput. Networks.

[14]  Murat Kuscu,et al.  An information theoretical analysis of broadcast networks and channel routing for FRET-based nanoscale communications , 2012, 2012 IEEE International Conference on Communications (ICC).

[15]  Raymond Bonnett,et al.  Photosensitizers of the porphyrin and phthalocyanine series for photodynamic therapy , 1995 .