The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance
暂无分享,去创建一个
A. Letai | D. Sugarbaker | R. Bueno | L. Coussens | D. Fennell | J. Ryan | D. Jablons | V. Broaddus | N. Kolhatkar | D. Barbone | A. Chacko | D. Sugarbaker | L. Coussens | Nikita S. Kolhatkar | J. Ryan
[1] A. McBride,et al. Proteasome inhibitors in the treatment of multiple myeloma , 2013, Expert review of anticancer therapy.
[2] Sven Diederichs,et al. The hallmarks of cancer , 2012, RNA biology.
[3] M. Butterworth,et al. Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells , 2010, Haematologica.
[4] A. Letai,et al. Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes , 2010, Proceedings of the National Academy of Sciences.
[5] A. Gartel,et al. ARC Synergizes with ABT-737 to Induce Apoptosis in Human Cancer Cells , 2010, Molecular Cancer Therapeutics.
[6] G. Scagliotti,et al. A randomized phase II study of bortezomib and pemetrexed, in combination or alone, in patients with previously treated advanced non-small-cell lung cancer. , 2010, Lung cancer.
[7] Lidong Zhang,et al. Open Access Research Characterization of Bortezomib-adapted I-45 Mesothelioma Cells , 2022 .
[8] Derek W. Yecies,et al. Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1. , 2010, Blood.
[9] S. Grant,et al. Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1 , 2009, Molecular and Cellular Biology.
[10] M. Yaffe,et al. Exploiting synthetic lethal interactions for targeted cancer therapy , 2009, Cell cycle.
[11] Tae-Hyoung Kim,et al. Effects of the BH3‐only protein human Noxa on mitochondrial dynamics , 2009, FEBS letters.
[12] D. Fennell,et al. Bcl-2 family proteins contribute to apoptotic resistance in lung cancer multicellular spheroids. , 2009, American journal of respiratory cell and molecular biology.
[13] P. Henklein,et al. The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[14] M. Giovannini,et al. Malignant pleural mesothelioma cells resist anoikis as quiescent pluricellular aggregates , 2009, Cell Death and Differentiation.
[15] J. Litz,et al. Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737 , 2009, Molecular Cancer Therapeutics.
[16] Valerie M. Weaver,et al. A tense situation: forcing tumour progression , 2009, Nature Reviews Cancer.
[17] G. Gordon,et al. mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids. , 2008, American journal of respiratory cell and molecular biology.
[18] Jeffrey R. Morgan,et al. Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids* , 2008, Journal of Biological Chemistry.
[19] R. Sposto,et al. Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. , 2008, Journal of the National Cancer Institute.
[20] G. Gordon,et al. Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma , 2008, Cancer Chemotherapy and Pharmacology.
[21] K. O'Byrne,et al. Advances in the systemic therapy of malignant pleural mesothelioma , 2008, Nature Clinical Practice Oncology.
[22] P. Dent,et al. Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate. , 2007, Blood.
[23] C. Porta,et al. Bortezomib Inhibits Nuclear Factor-κB–Dependent Survival and Has Potent In vivo Activity in Mesothelioma , 2007, Clinical Cancer Research.
[24] F. Pampaloni,et al. The third dimension bridges the gap between cell culture and live tissue , 2007, Nature Reviews Molecular Cell Biology.
[25] D. Fennell,et al. BCL-2 family regulation by the 20S proteasome inhibitor bortezomib , 2007, Oncogene.
[26] Tomomi Gotoh,et al. ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim , 2007, Cell.
[27] W. Hou,et al. Functional Linkage between NOXA and Bim in Mitochondrial Apoptotic Events* , 2007, Journal of Biological Chemistry.
[28] R. Bataille,et al. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma. , 2007, Cancer research.
[29] C. Scott,et al. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. , 2006, Cancer cell.
[30] Keiran S. M. Smalley,et al. Life ins't flat: Taking cancer biology to the next dimension , 2006, In Vitro Cellular & Developmental Biology - Animal.
[31] M. Soengas,et al. Proteasome Inhibitor PS-341 Induces Apoptosis in Cisplatin-resistant Squamous Cell Carcinoma Cells by Induction of Noxa* , 2006, Journal of Biological Chemistry.
[32] S. Armstrong,et al. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. , 2006, Cancer cell.
[33] D. Jablons,et al. A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance. , 2005, American journal of respiratory cell and molecular biology.
[34] S. Lowe,et al. Intrinsic tumour suppression , 2004, Nature.
[35] D. Fennell,et al. Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development. , 2004, The Lancet. Oncology.
[36] F. Khuri,et al. Novel agents and incremental advances in the treatment of head and neck cancer. , 2004, Seminars in oncology.
[37] Scott W. Lowe,et al. Apoptosis A Link between Cancer Genetics and Chemotherapy , 2002, Cell.
[38] E. Campo,et al. The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. , 2006, Blood.
[39] S. Futaki. Oligoarginine vectors for intracellular delivery: design and cellular-uptake mechanisms. , 2006, Biopolymers.
[40] W. Dalton,et al. The proteasome. , 2004, Seminars in oncology.