Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man

[1]  U. Klotz,et al.  Specific measurement of 5-aminosalicylic acid and its acetylated metabolite in human bile. , 1983, British journal of clinical pharmacology.

[2]  S. Hansen,et al.  5-aminosalicylic acid in a slow-release preparation: bioavailability, plasma level, and excretion in humans. , 1982, Gastroenterology.

[3]  K. Das,et al.  Absorption, enterohepatic circulation, and excretion of 5-aminosalicylic acid in rats. , 1982, The American journal of gastroenterology.

[4]  S. Hansen.  Assay of 5-aminosalicylate and its acetylated metabolite in biological fluids by high-performance liquid chromatography on dynamically modified silica. , 1981, Journal of chromatography.

[5]  U. Klotz,et al.  Simplified high-performance liquid chromatographic method for 5-aminosalicylic acid in plasma and urine. , 1981, Journal of chromatography.

[6]  Truelove Sc.  The treatment of ulcerative colitis. , 1981 .

[7]  G. Labó,et al.  TREATMENT OF ULCERATIVE COLITIS WITH HIGH-DOSE 5-AMINOSALICYLIC ACID ENEMAS , 1981, The Lancet.

[8]  E. Hudson,et al.  Sulphasalazine and male infertility: reversibility and possible mechanism. , 1981, Gut.

[9]  S. Truelove.  The treatment of ulcerative colitis. , 1981, Schweizerische medizinische Wochenschrift.

[10]  K Heinkel,et al.  Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. , 1980, The New England journal of medicine.

[11]  J. V. van Tongeren,et al.  Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine. , 1980, Gut.

[12]  S. Truelove,et al.  The effect of topical N-acetyl-5-aminosalicylic acid in ulcerative colitis. , 1980, Scandinavian journal of gastroenterology.

[13]  H. Pieniaszek,et al.  Capacity-limited gut wall metabolism of 5-aminosalicylic acid, a therapeutically active metabolite of sulfasalazine, in rats. , 1979, Journal of pharmaceutical sciences.

[14]  H. Mekhjian,et al.  National Cooperative Crohn's Disease Study: adverse reactions to study drugs. , 1979, Gastroenterology.

[15]  S. Truelove,et al.  AN EXPERIMENT TO DETERMINE THE ACTIVE THERAPEUTIC MOIETY OF SULPHASALAZINE , 1977, The Lancet.

[16]  K. Das,et al.  Clinical Pharmacokinetics of Sulphasalazine , 1976, Clinical pharmacokinetics.

[17]  J. McManus,et al.  Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. , 1973, The New England journal of medicine.

[18]  Thomas We,et al.  Enteric fever apparently spread by pasteurized milk. , 1948 .