The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies
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E. Schwarz | L. Calvi | J. Liesveld | L. Xing | M. Becker | Hengwei Zhang | B. Lipe | Shu-Chi A. Yeh
[1] R. Turcotte,et al. Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging , 2022, Nature Methods.
[2] E. McNeil,et al. Publisher Correction: Musculoskeletal involvement in childhood leukemia: Characteristics and survival outcomes , 2022, Pediatric Rheumatology.
[3] Corbin E. Meacham,et al. Adiponectin receptors sustain hematopoietic stem cells throughout adulthood by protecting them from inflammation , 2022, Nature Cell Biology.
[4] L. Xing,et al. Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice , 2022, The Journal of clinical investigation.
[5] J. Krijgsveld,et al. Specific inflammatory osteoclast precursors induced during chronic inflammation give rise to highly active osteoclasts associated with inflammatory bone loss , 2022, Bone Research.
[6] Xiaolei Tang,et al. Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation. , 2022, American journal of physiology. Cell physiology.
[7] N. LeBrasseur,et al. Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity , 2022, Aging cell.
[8] P. Libby,et al. B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis , 2022, Nature Immunology.
[9] Xi-Ping Huang,et al. Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia , 2022, Cancer discovery.
[10] P. Schneider,et al. Receptor Activator of NF-κB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course , 2021, Cancers.
[11] David M. Evans,et al. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis , 2021, The Journal of experimental medicine.
[12] S. M. Tariq,et al. A comprehensive review of the impact of obesity on plasma cell disorders , 2021, Leukemia.
[13] G. Müller-Newen,et al. Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization , 2021, Leukemia.
[14] E. Sikora,et al. A common signature of cellular senescence; does it exist? , 2021, Ageing Research Reviews.
[15] E. Forsberg,et al. Acute and endothelial-specific Robo4 deletion affect hematopoietic stem cell trafficking independent of VCAM1 , 2021, PloS one.
[16] Rachel E. Brewer,et al. Aged skeletal stem cells generate an inflammatory degenerative niche , 2021, Nature.
[17] C. Edwards,et al. Myeloma and marrow adiposity: Unanswered questions and future directions. , 2021, Best practice & research. Clinical endocrinology & metabolism.
[18] T. L. Andersen,et al. Myeloma-bone marrow adipocyte axis in tumour survival and treatment response , 2021, British Journal of Cancer.
[19] A. Chalk,et al. The characterization of distinct populations of murine skeletal cells that have different roles in B lymphopoiesis. , 2021, Blood.
[20] P. Tang,et al. Skeleton-vasculature chain reaction: a novel insight into the mystery of homeostasis , 2021, Bone Research.
[21] F. Camargo,et al. Quantification of bone marrow interstitial pH and calcium concentration by intravital ratiometric imaging , 2021, Nature communications.
[22] S. Morrison,et al. A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis , 2021, Nature.
[23] J. D. Engel,et al. In situ mapping identifies distinct vascular niches for myelopoiesis , 2021, Nature.
[24] Nancie J. MacIver,et al. The Role of the Adipokine Leptin in Immune Cell Function in Health and Disease , 2021, Frontiers in Immunology.
[25] J. Edwards,et al. Adiponectin signalling in bone homeostasis, with age and in disease , 2021, Bone Research.
[26] D. Hume,et al. Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice , 2021, Journal of Hematology & Oncology.
[27] Junke Zheng,et al. Bone marrow niche ATP levels determine leukemia-initiating cell activity via P2X7 in leukemic models. , 2020, The Journal of clinical investigation.
[28] T. Witham,et al. Quantitative 3D imaging of the cranial microvascular environment at single-cell resolution , 2020, Nature Communications.
[29] Gary D Bader,et al. Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation. , 2020, Blood cancer discovery.
[30] G. Pei,et al. Schwann cells promote prevascularization and osteogenesis of tissue-engineered bone via bone marrow mesenchymal stem cell-derived endothelial cells , 2020, Stem cell research & therapy.
[31] Caroline Wilson,et al. Oestrogen and zoledronic acid driven changes to the bone and immune environments: Potential mechanisms underlying the differential anti-tumour effects of zoledronic acid in pre- and post-menopausal conditions , 2020, Journal of bone oncology.
[32] Anjali P. Kusumbe,et al. Bone Vasculature and Bone Marrow Vascular Niches in Health and Disease , 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[33] Hyunsook Kim,et al. Bone marrow adipogenic lineage precursors (MALPs) promote osteoclastogenesis in bone remodeling and pathologic bone loss , 2020, bioRxiv.
[34] E. Chiarella,et al. Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells , 2020, Heliyon.
[35] Michael R. Tallack,et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance , 2020, Nature Communications.
[36] Mingyao Li,et al. Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment , 2020, eLife.
[37] J. Gribben,et al. Bone marrow niches in haematological malignancies , 2020, Nature Reviews Cancer.
[38] Seung Hun Lee,et al. Regulation of bone metabolism by megakaryocytes in a paracrine manner , 2020, Scientific Reports.
[39] Seung Hun Lee,et al. Regulation of bone metabolism by megakaryocytes in a paracrine manner , 2020, Scientific Reports.
[40] C. Burger,et al. Osteoimmunology: A Current Update of the Interplay Between Bone and the Immune System , 2020, Frontiers in Immunology.
[41] D. Spandidos,et al. Telomere length and telomerase activity in osteoporosis and osteoarthritis , 2019, Experimental and therapeutic medicine.
[42] Guoji Guo,et al. Live-animal imaging of native hematopoietic stem and progenitor cells , 2019, Nature.
[43] P. Waterhouse,et al. Metalloproteases: On the Watch in the Hematopoietic Niche. , 2019, Trends in immunology.
[44] H. Pahl,et al. Enhanced expression of the sphingosine-1-phosphate-receptor-3 causes acute myelogenous leukemia in mice , 2019, Leukemia.
[45] T. Hla,et al. Sphingosine 1-phosphate: Lipid signaling in pathology and therapy , 2019, Science.
[46] Anjali P. Kusumbe,et al. Role of angiocrine signals in bone development, homeostasis and disease , 2019, Open Biology.
[47] A. Trumpp,et al. Haematopoietic stem cells in perisinusoidal niches are protected from ageing , 2019, Nature Cell Biology.
[48] John M. Ashton,et al. Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support , 2019, Leukemia.
[49] C. López-Otín,et al. Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging , 2019, Cell stem cell.
[50] Bin Huang,et al. CXCL2 attenuates osteoblast differentiation by inhibiting the ERK1/2 signaling pathway , 2019, Journal of Cell Science.
[51] Patrick M. Helbling,et al. Global transcriptomic profiling of the bone marrow stromal microenvironment during postnatal development, aging and inflammation , 2019, bioRxiv.
[52] Daohong Zhou. Faculty Opinions recommendation of A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia. , 2019, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.
[53] Monika S. Kowalczyk,et al. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia , 2019, Cell.
[54] Angel Y. F. Kam,et al. CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation , 2019, Stem cell reports.
[55] Michael R. Elliott,et al. Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B. , 2019, JCI insight.
[56] R. Satija,et al. The bone marrow microenvironment at single-cell resolution , 2019, Nature.
[57] Jianbo He,et al. Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells. , 2019, Cell stem cell.
[58] F. Delhommeau,et al. Systemic Dysfunction of Osteoblast Differentiation in Adipose-Derived Stem Cells from Patients with Multiple Myeloma , 2019, Cells.
[59] H. Snoeck,et al. Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro. , 2019, Cell stem cell.
[60] Martin C. Müller,et al. The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis , 2019, Haematologica.
[61] N. Rucci,et al. Updates on Osteoimmunology: What's New on the Cross-Talk Between Bone and Immune System , 2019, Front. Endocrinol..
[62] Austin J. Ramme,et al. Age-related inflammation triggers skeletal stem/progenitor cell dysfunction , 2019, Proceedings of the National Academy of Sciences.
[63] A. List,et al. The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes. , 2019, Blood.
[64] M. Raaijmakers,et al. The mesenchymal niche in MDS. , 2019, Blood.
[65] S. Morrison,et al. Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow. , 2019, Cell stem cell.
[66] D. Casero,et al. Lymphoid-Biased Hematopoietic Stem Cells Are Maintained with Age and Efficiently Generate Lymphoid Progeny , 2019, Stem cell reports.
[67] L. Calvi,et al. Impact of aging on bone, marrow and their interactions. , 2019, Bone.
[68] Xi C. He,et al. N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells. , 2019, Cell reports.
[69] A. Verma,et al. Myelodysplastic Syndrome Progression to Acute Myeloid Leukemia at the Stem Cell Level , 2018, Nature Medicine.
[70] P. Frenette,et al. Neural Regulation of Bone and Bone Marrow. , 2018, Cold Spring Harbor perspectives in medicine.
[71] Marc N. Wein,et al. Regulation of Bone Remodeling by Parathyroid Hormone. , 2018, Cold Spring Harbor perspectives in medicine.
[72] Walter de Back,et al. Hematopoietic Stem Cells in Perisinusoidal Niches are Protected From Aging , 2018, Experimental Hematology.
[73] J. E. Park,et al. Next‐generation proteasome inhibitors for cancer therapy , 2018, Translational research : the journal of laboratory and clinical medicine.
[74] Samuel E. Zimmerman,et al. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow , 2018, Nature Communications.
[75] U. Germing,et al. Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia , 2018, Haematologica.
[76] Sida Zhao,et al. Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells , 2018, Cell Death & Disease.
[77] J. Martinez-Barbera,et al. Paracrine roles of cellular senescence in promoting tumourigenesis , 2018, British Journal of Cancer.
[78] P. Frenette,et al. Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches. , 2018, Developmental cell.
[79] Christopher A. Miller,et al. Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant. , 2018, JCI insight.
[80] E. Schwarz,et al. Osteoblast–osteoclast interactions , 2018, Connective tissue research.
[81] S. Seno,et al. Direct cell–cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo , 2018, Nature Communications.
[82] Yongwon Choi,et al. Updating osteoimmunology: regulation of bone cells by innate and adaptive immunity , 2018, Nature Reviews Rheumatology.
[83] Catriona McLean,et al. Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML , 2018, Cell stem cell.
[84] V. Gudnason,et al. Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study. , 2017, Blood advances.
[85] J. Hong,et al. Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function. , 2017, Blood advances.
[86] A. Banfi,et al. It Takes Two to Tango: Coupling of Angiogenesis and Osteogenesis for Bone Regeneration , 2017, Front. Bioeng. Biotechnol..
[87] M. Dimopoulos,et al. Mechanisms of bone destruction in multiple myeloma , 2017, European journal of cancer care.
[88] L. Calvi,et al. The microenvironment in myelodysplastic syndromes: Niche-mediated disease initiation and progression. , 2017, Experimental hematology.
[89] D. Hume,et al. CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. , 2017, Biomaterials.
[90] Y. Degboé,et al. DKK1 and sclerostin are early markers of relapse in multiple myeloma. , 2017, Bone.
[91] C. Chen,et al. Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion , 2017, Leukemia.
[92] C. Schütte,et al. Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[93] N. LeBrasseur,et al. Targeting cellular senescence prevents age-related bone loss in mice , 2017, Nature Medicine.
[94] R. Davis,et al. AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth. , 2017, JCI insight.
[95] S. Gabriel,et al. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease , 2017, The New England journal of medicine.
[96] O. Naveiras,et al. Bone marrow adipocytes promote the regeneration of stem cells and hematopoiesis by secreting SCF , 2017, Nature Cell Biology.
[97] A. Scialdone,et al. Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration , 2017, Cell stem cell.
[98] M. L. Le Beau,et al. Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model. , 2017, Blood.
[99] Satoru Miyano,et al. Clonal evolution in myelodysplastic syndromes , 2017, Nature Communications.
[100] N. Raje,et al. Myeloma bone disease: pathogenesis and treatment. , 2017, Clinical advances in hematology & oncology : H&O.
[101] Nicola J. Brown,et al. Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells , 2017, Breast Cancer Research.
[102] F. Kirchhoff,et al. Osteopontin attenuates aging‐associated phenotypes of hematopoietic stem cells , 2017, The EMBO journal.
[103] Matthew A. Cooper,et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice , 2017, Science.
[104] Nicolas F. Fernandez,et al. Differential cytokine contributions of perivascular haematopoietic stem cell niches , 2017, Nature Cell Biology.
[105] L. Hofbauer,et al. Myelodysplastic syndromes and bone loss in mice and men , 2017, Leukemia.
[106] G. Colditz,et al. Obesity and the Transformation of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma: A Population-Based Cohort Study , 2016, Journal of the National Cancer Institute.
[107] J. Cleveland,et al. The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype. , 2016, Blood.
[108] S. Miyano,et al. Dynamics of clonal evolution in myelodysplastic syndromes , 2016, Nature Genetics.
[109] D. Kazandjian. Multiple myeloma epidemiology and survival: A unique malignancy. , 2016, Seminars in oncology.
[110] C. Chuah,et al. CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. , 2016, Cancer cell.
[111] R. Greil,et al. T cells in multiple myeloma display features of exhaustion and senescence at the tumor site , 2016, Journal of Hematology & Oncology.
[112] T. Trotter,et al. Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone. , 2016, The American journal of pathology.
[113] Charles P. Lin,et al. Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators. , 2016, Cell stem cell.
[114] Kai Hu,et al. The roles of vascular endothelial growth factor in bone repair and regeneration. , 2016, Bone.
[115] S. Gupta,et al. IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation , 2016, Scientific Reports.
[116] P. Shi,et al. Type I insulin-like growth factor receptor signaling in hematological malignancies , 2016, Oncotarget.
[117] N. Nassif,et al. Multiple myeloma causes clonal T-cell immunosenescence: identification of potential novel targets for promoting tumour immunity and implications for checkpoint blockade , 2016, Leukemia.
[118] R. Adams,et al. Blood vessel formation and function in bone , 2016, Development.
[119] N. Munshi,et al. APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment. , 2016, Blood.
[120] S. Morrison,et al. Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow. , 2016, Cell stem cell.
[121] L. Suva,et al. The effects of proteasome inhibitors on bone remodeling in multiple myeloma. , 2016, Bone.
[122] J. Siddiqui,et al. Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement. , 2016, Physiology.
[123] Charles P. Lin,et al. Distinct bone marrow blood vessels differentially regulate hematopoiesis , 2016, Nature.
[124] C. Betsholtz,et al. Age-dependent modulation of vascular niches for haematopoietic stem cells , 2016, Nature.
[125] E. Pietras,et al. Chronic interleukin-1 drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal , 2016, Nature Cell Biology.
[126] Ron-Patrick Cadeddu,et al. Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia , 2016, Leukemia.
[127] L. Calvi,et al. Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome. , 2016, Blood.
[128] R. Orlowski,et al. Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation , 2015, Oncotarget.
[129] T. Cheng,et al. Targeting stem cell niche can protect hematopoietic stem cells from chemotherapy and G-CSF treatment , 2015, Stem Cell Research & Therapy.
[130] K. Matsuo,et al. EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance , 2015, Stem cells.
[131] Zhiyu Zhao,et al. Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal , 2015, Nature.
[132] B. Ebert,et al. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. , 2015, Blood.
[133] C. Panaroni,et al. PTH Signaling in Osteoprogenitors Is Essential for B‐Lymphocyte Differentiation and Mobilization , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[134] S. Karlsson,et al. TGF-β signaling in the control of hematopoietic stem cells. , 2015, Blood.
[135] Xiang-hang Luo,et al. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. , 2015, The Journal of clinical investigation.
[136] E. Passegué,et al. Normal and leukemic stem cell niches: insights and therapeutic opportunities. , 2015, Cell stem cell.
[137] F. Aversa,et al. The osteoblastic niche in the context of multiple myeloma , 2015, Annals of the New York Academy of Sciences.
[138] J. Hoeijmakers,et al. An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. , 2014, Developmental cell.
[139] Xiao Li,et al. Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes , 2014, European journal of haematology.
[140] T. Suda,et al. Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin. , 2014, Biochemical and biophysical research communications.
[141] Hans Erik Johnsen,et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. , 2014, The Lancet. Oncology.
[142] Xi C. He,et al. Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells , 2014, Nature Medicine.
[143] S. Armstrong,et al. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. , 2014, Cell stem cell.
[144] L. Duong,et al. PDGF-BB secreted by preosteoclasts induces CD31hiEmcnhi vessel subtype in coupling osteogenesis , 2014, Nature Medicine.
[145] D. Lai,et al. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms , 2014, Nature.
[146] A. Trumpp,et al. Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit. , 2014, Cell stem cell.
[147] A. Sundan,et al. The role of bone morphogenetic proteins in myeloma cell survival. , 2014, Cytokine & growth factor reviews.
[148] N. Sims,et al. Osteoimmunology: oncostatin M as a pleiotropic regulator of bone formation and resorption in health and disease. , 2014, BoneKEy reports.
[149] R. Proia,et al. Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo. , 2014, The Journal of clinical investigation.
[150] Y. Kunisaki,et al. Influences of vascular niches on hematopoietic stem cell fate , 2014, International Journal of Hematology.
[151] K. Ikeda,et al. Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL* , 2014, The Journal of Biological Chemistry.
[152] R. Adams,et al. Endothelial Notch activity promotes angiogenesis and osteogenesis in bone , 2014, Nature.
[153] R. Adams,et al. Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone , 2014, Nature.
[154] C. Shao,et al. An Osteopontin‐Integrin Interaction Plays a Critical Role in Directing Adipogenesis and Osteogenesis by Mesenchymal Stem Cells , 2014, Stem cells.
[155] S. Morrison,et al. The bone marrow niche for haematopoietic stem cells , 2014, Nature.
[156] R. Rabadán,et al. Leukemogenesis Induced by an Activating β-catenin mutation in Osteoblasts , 2014, Nature.
[157] A. Bergman,et al. Megakaryocytes regulate hematopoietic stem cell quiescence via Cxcl4 secretion , 2013, Nature Medicine.
[158] F. Zhou,et al. Dickkopf-1 is a key regulator of myeloma bone disease: opportunities and challenges for therapeutic intervention. , 2013, Blood reviews.
[159] A. Bergman,et al. Arteriolar niches maintain haematopoietic stem cell quiescence , 2013, Nature.
[160] M. Schweizer,et al. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C‐C motif) ligand 5 (Ccl5) , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[161] I. Bruns,et al. Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells , 2013, Leukemia.
[162] C. Panaroni,et al. Interactions Between B Lymphocytes and the Osteoblast Lineage in Bone Marrow , 2013, Calcified Tissue International.
[163] T. Olson,et al. Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning. , 2013, Blood.
[164] D. Sipkins,et al. LYMPHOID NEOPLASIA Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy , 2013 .
[165] G. Roodman,et al. Myeloma bone disease: Pathophysiology and management , 2013, Journal of bone oncology.
[166] S. Nutt,et al. M-CSF instructs myeloid lineage fate in single haematopoietic stem cells , 2013, Nature.
[167] I. Bruns,et al. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration , 2013, Nature Medicine.
[168] L. Lagneaux,et al. Evidences of Early Senescence in Multiple Myeloma Bone Marrow Mesenchymal Stromal Cells , 2013, PloS one.
[169] Y. Yu,et al. Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1 , 2013, Leukemia.
[170] S. Morrison,et al. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches , 2013, Nature.
[171] R. Taichman,et al. The effects of zoledronic acid in the bone and vasculature support of hematopoietic stem cell niches , 2013, Journal of cellular biochemistry.
[172] D. Scadden,et al. Differential regulation of myeloid leukemias by the bone marrow microenvironment , 2012, Nature Medicine.
[173] L. Idolazzi,et al. Sclerostin and DKK1 in postmenopausal osteoporosis treated with denosumab , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[174] J. Lévesque,et al. Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance , 2012, Nature Medicine.
[175] A. Zallone,et al. Skeletal parasympathetic innervation communicates central IL-1 signals regulating bone mass accrual , 2012, Proceedings of the National Academy of Sciences.
[176] M. Penichet,et al. TRAF6 activation in multiple myeloma: a potential therapeutic target. , 2012, Clinical lymphoma, myeloma & leukemia.
[177] A. Rabie,et al. The role of vascular endothelial growth factor in ossification , 2012, International Journal of Oral Science.
[178] W. Hiddemann,et al. Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients. , 2012, Blood.
[179] Nathan C Boles,et al. Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. , 2012, Blood.
[180] E. Sitnicka,et al. Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow , 2012, The Journal of experimental medicine.
[181] J. Dipersio,et al. Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice. , 2012, Blood.
[182] R. Kyle,et al. Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease. , 2011, Blood.
[183] A. Iwama,et al. Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche , 2011, Cell.
[184] B. Barlogie,et al. NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity. , 2011, Experimental hematology.
[185] John M. Ashton,et al. Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia. , 2011, Blood.
[186] I. Ghobrial,et al. Multiple Myeloma Mesenchymal Stem Cells: Characterization, Origin, and Tumor-Promoting Effects , 2011, Clinical Cancer Research.
[187] S. Takeda,et al. Sympathetic control of bone mass regulated by osteopontin , 2011, Proceedings of the National Academy of Sciences.
[188] Charles P. Lin,et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche , 2011, Nature.
[189] S. Deaglio,et al. Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease. , 2011, Leukemia research.
[190] M. Bitzer,et al. Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase. , 2011, Cancer research.
[191] R. Pacifici,et al. Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand , 2010, Proceedings of the National Academy of Sciences.
[192] D. Kaplan,et al. Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. , 2010, Cancer research.
[193] J. Lévesque,et al. The endosteal ‘osteoblastic’ niche and its role in hematopoietic stem cell homing and mobilization , 2010, Leukemia.
[194] Yang Liu,et al. Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice. , 2010, The Journal of clinical investigation.
[195] U. Mellqvist,et al. Monoclonal gammopathy of undetermined significance and risk of skeletal fractures: a population-based study. , 2010, Blood.
[196] C. Yao,et al. Survivin is upregulated in myeloma cell lines cocultured with mesenchymal stem cells. , 2010, Leukemia research.
[197] S. Rajkumar,et al. Prevalence of monoclonal gammopathy of undetermined significance: a systematic review. , 2010, Mayo Clinic proceedings.
[198] H. Kronenberg,et al. Disruption of PTH Receptor 1 in T Cells Protects against PTH-Induced Bone Loss , 2010, PloS one.
[199] Ben D. MacArthur,et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche , 2010, Nature.
[200] Liza J. Raggatt,et al. Cellular and Molecular Mechanisms of Bone Remodeling* , 2010, The Journal of Biological Chemistry.
[201] David A. Williams,et al. The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. , 2010, Blood.
[202] I. Charo,et al. CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice. , 2010, The Journal of clinical investigation.
[203] K. Yata,et al. TGF-β Inhibition Restores Terminal Osteoblast Differentiation to Suppress Myeloma Growth , 2010, PloS one.
[204] Charles P. Lin,et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukemia , 2010, Nature.
[205] Ian A. White,et al. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. , 2010, Cell stem cell.
[206] J. Campisi,et al. The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.
[207] S. Shapiro,et al. Osteoclasts are important for bone angiogenesis. , 2010, Blood.
[208] J. Fraumeni,et al. Obesity is associated with an increased risk of monoclonal gammopathy of undetermined significance among black and white women. , 2009, Blood.
[209] Cheang Ly Be,et al. Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. , 2009, Blood.
[210] R. Hayes,et al. Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study. , 2009, Blood.
[211] G. Daley,et al. Bone marrow adipocytes as negative regulators of the hematopoietic microenvironment , 2009, Nature.
[212] A. McMahon,et al. Osteoblastic regulation of B lymphopoiesis is mediated by Gsα-dependent signaling pathways , 2008, Proceedings of the National Academy of Sciences.
[213] Siu-Fun Wong,et al. Zoledronic Acid Markedly Improves Bone Mineral Density for Patients with Monoclonal Gammopathy of Undetermined Significance and Bone Loss , 2008, Clinical Cancer Research.
[214] M. Boccadoro,et al. A multicenter, randomized clinical trial comparing zoledronic acid versus observation in patients with asymptomatic myeloma , 2008, Cancer.
[215] David A. Hume,et al. Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo1 , 2008, The Journal of Immunology.
[216] S. Yaccoby,et al. Role of decorin in the antimyeloma effects of osteoblasts. , 2008, Blood.
[217] O. Stephens,et al. Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma. , 2008, Blood.
[218] Daniel Lucas,et al. Haematopoietic stem cell release is regulated by circadian oscillations , 2008, Nature.
[219] M. Zwahlen,et al. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies , 2008, The Lancet.
[220] A. Wright,et al. Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis , 2008, Aging cell.
[221] A. Cope,et al. Treg cells suppress osteoclast formation: a new link between the immune system and bone. , 2007, Arthritis and rheumatism.
[222] W. Franz,et al. Primary hyperparathyroidism is associated with increased circulating bone marrow-derived progenitor cells. , 2007, American journal of physiology. Endocrinology and metabolism.
[223] Satoshi Tanaka,et al. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region , 2007, Nature Biotechnology.
[224] A. Órfão,et al. New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells. , 2007, Blood.
[225] Kenneth C. Anderson,et al. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets , 2007, Nature Reviews Cancer.
[226] A. Trumpp,et al. Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment , 2007, Nature Medicine.
[227] Younghun Jung,et al. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. , 2007, Blood.
[228] N. Mochizuki,et al. Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice. , 2007, Blood.
[229] A. Saltiel,et al. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. , 2007, The Journal of clinical investigation.
[230] T. Suda,et al. Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. , 2006, Cell metabolism.
[231] Ari Elson,et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells , 2006, Nature Medicine.
[232] H. Weiner,et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells , 2006, Nature.
[233] Terry M Therneau,et al. Prevalence of monoclonal gammopathy of undetermined significance. , 2006, The New England journal of medicine.
[234] E. Brown,et al. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor , 2006, Nature.
[235] P. Frenette,et al. Signals from the Sympathetic Nervous System Regulate Hematopoietic Stem Cell Egress from Bone Marrow , 2006, Cell.
[236] E. Schwarz,et al. Osteoclast precursors, RANKL/RANK, and immunology , 2005, Immunological reviews.
[237] S. Rafii,et al. The bone marrow vascular niche: home of HSC differentiation and mobilization. , 2005, Physiology.
[238] O. Sezer. Myeloma bone disease , 2005, Hematology.
[239] B. Williams,et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. , 2005, Blood.
[240] S. Morrison,et al. Supplemental Experimental Procedures , 2022 .
[241] Y. Ko,et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size , 2005, The Journal of experimental medicine.
[242] Masaki Noda,et al. Leptin regulation of bone resorption by the sympathetic nervous system and CART , 2005, Nature.
[243] M. Suga,et al. Differentiation, Maturation, and Survival of Dendritic Cells by Osteopontin Regulation , 2005, Clinical Diagnostic Laboratory Immunology.
[244] T. Therneau,et al. Long-term follow-up of 241 patients with monoclonal gammopathy of undetermined significance: the original Mayo Clinic series 25 years later. , 2004, Mayo Clinic proceedings.
[245] G. Roodman. Mechanisms of bone metastasis. , 2004, Discovery medicine.
[246] B. Harder,et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. , 2004, Blood.
[247] D. Scadden,et al. Osteoblastic cells regulate the haematopoietic stem cell niche , 2003, Nature.
[248] Haiyang Huang,et al. Identification of the haematopoietic stem cell niche and control of the niche size , 2003, Nature.
[249] G. Avvisati,et al. Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[250] W. Berdel,et al. Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma. , 2003, Blood.
[251] E. van Marck,et al. Zoledronic Acid Treatment of 5T2MM‐Bearing Mice Inhibits the Development of Myeloma Bone Disease: Evidence for Decreased Osteolysis, Tumor Burden and Angiogenesis, and Increased Survival , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[252] K. Anderson,et al. The extracellular calcium Ca2+o-sensing receptor is expressed in myeloma cells and modulates cell proliferation. , 2002, Biochemical and biophysical research communications.
[253] L. Devy,et al. Novel Antiangiogenic Effects of the Bisphosphonate Compound Zoledronic Acid , 2002, Journal of Pharmacology and Experimental Therapeutics.
[254] O. Sezer,et al. Angiogenesis in multiple myeloma. , 2002, Leukemia research.
[255] Sundeep Khosla,et al. Sex steroids and the construction and conservation of the adult skeleton. , 2002, Endocrine reviews.
[256] S. Rafii,et al. Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand , 2002, Cell.
[257] S. Rafii,et al. Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors , 2002, Gene Therapy.
[258] P. Richardson,et al. Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications , 2001, Leukemia.
[259] C. Overall,et al. Matrix Metalloproteinase Activity Inactivates the CXC Chemokine Stromal Cell-derived Factor-1* , 2001, The Journal of Biological Chemistry.
[260] A. Spradling,et al. Stem cells find their niche , 2001, Nature.
[261] M. Noda,et al. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. , 2001, The Journal of clinical investigation.
[262] G. Rodan,et al. In vivo effects of bisphosphonates on the osteoclast mevalonate pathway. , 2000, Endocrinology.
[263] B. Klein,et al. Insulin‐like growth factor induces the survival and proliferation of myeloma cells through an interleukin‐6‐independent transduction pathway , 2000, British journal of haematology.
[264] M. Elmlinger,et al. Bone Turnover and Growth During and After Continuing Chemotherapy in Children with Acute Lymphoblastic Leukemia , 2000, Pediatric Research.
[265] R. Fonseca,et al. Prognostic value of bone marrow angiogenesis in multiple myeloma. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[266] S. Rafii,et al. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[267] R. Bataille,et al. Quantifiable excess of bone resorption in monoclonal gammopathy is an early symptom of malignancy: a prospective study of 87 bone biopsies. , 1996, Blood.
[268] S. Kasugai,et al. Regulation of Osteopontin Expression in Osteoblasts , 1995, Annals of the New York Academy of Sciences.
[269] K. Anderson,et al. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. , 1993, Blood.
[270] J. Kanis,et al. Abnormal bone remodelling in patients with myelomatosis and normal biochemical indices of bone resorption , 1992, European journal of haematology.
[271] M. Freeman,et al. A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. , 1991, Science.
[272] Florent Elefteriou,et al. Control of Bone Remodeling by the Peripheral Sympathetic Nervous System , 2013, Calcified Tissue International.
[273] Kai-Yan Liu,et al. Hematopoietic recovery following chemotherapy is improved by BADGE-induced inhibition of adipogenesis , 2012, International Journal of Hematology.
[274] Toshio Matsumoto,et al. TGF-β-related mechanisms of bone destruction in multiple myeloma. , 2011, Bone.
[275] 竹内 恭子. TGF-β inhibition restores terminal osteoblast differentiation to suppress myeloma growth , 2010 .
[276] H. Fox,et al. In vivo osteopontin-induced macrophage accumulation is dependent on CD44 expression. , 2008, Cellular immunology.
[277] L. Frölich,et al. Impact of aging , 2007, NeuroMolecular Medicine.
[278] T. Hentunen,et al. Osteocytes inhibit osteoclastic bone resorption through transforming growth factor‐β: Enhancement by estrogen * , 2002, Journal of cellular biochemistry.
[279] Pamela J. Hines,et al. Repair and Regeneration. , 2017, Science.
[280] E. Pietras,et al. Chronic interleukin-1 drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal , 2016, Nature Cell Biology.