Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation

[1]  Eric C. Lai,et al.  The m6A pathway facilitates sex determination in Drosophila , 2017, Nature Communications.

[2]  T. Nilsen,et al.  Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication , 2017, Journal of Virology.

[3]  Douglas L Black,et al.  m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover , 2017, Genes & development.

[4]  M. Rao,et al.  Mrhl Long Noncoding RNA Mediates Meiotic Commitment of Mouse Spermatogonial Cells by Regulating Sox8 Expression , 2017, Molecular and Cellular Biology.

[5]  Nian Liu,et al.  N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein , 2017, Nucleic acids research.

[6]  Yang Shi,et al.  m6A RNA methylation regulates the UV-induced DNA damage response , 2016, Nature.

[7]  Qianhua Xu,et al.  BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis , 2017, Nature Communications.

[8]  Yun-Gui Yang,et al.  Cytoplasmic m6A reader YTHDF3 promotes mRNA translation , 2017, Cell Research.

[9]  Chuan He,et al.  YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA , 2017, Cell Research.

[10]  Chuan He,et al.  m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition , 2016, Nature.

[11]  Chaolin Zhang,et al.  CLIP Tool Kit (CTK): a flexible and robust pipeline to analyze CLIP sequencing data , 2016, Bioinform..

[12]  F. Tang,et al.  Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions. , 2017, Cell stem cell.

[13]  Chuan He,et al.  Post-transcriptional gene regulation by mRNA modifications , 2016, Nature Reviews Molecular Cell Biology.

[14]  Nathan Archer,et al.  m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination , 2016, Nature.

[15]  Miguel A. Andrade-Navarro,et al.  m6A modulates neuronal functions and sex determination in Drosophila , 2016, Nature.

[16]  Samie R. Jaffrey,et al.  m6A RNA methylation promotes XIST-mediated transcriptional repression , 2016, Nature.

[17]  Zhe Liang,et al.  N(6)-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis. , 2016, Developmental cell.

[18]  Chuan He,et al.  Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. , 2016, Trends in genetics : TIG.

[19]  Samir Adhikari,et al.  Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. , 2016, Molecular cell.

[20]  M. Rao,et al.  Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells , 2015, Nucleic acids research.

[21]  Miao Yu,et al.  A METTL 3-METTL 14 complex mediates mammalian nuclear RNA N 6-adenosine methylation , 2016 .

[22]  Rong Wang,et al.  Coordination of m(6)A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming. , 2015, Cell stem cell.

[23]  Camille Stephan-Otto Attolini,et al.  Designing alternative splicing RNA-seq studies. Beyond generic guidelines , 2015, Bioinform..

[24]  Saeed Tavazoie,et al.  HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events , 2015, Cell.

[25]  Shu-Bing Qian,et al.  Dynamic m6A mRNA methylation directs translational control of heat shock response , 2015, Nature.

[26]  J. Zyprych-Walczak,et al.  The Impact of Normalization Methods on RNA-Seq Data Analysis , 2015, BioMed research international.

[27]  Christopher E. Mason,et al.  Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome , 2015, Nature Methods.

[28]  Chuan He,et al.  N 6 -methyladenosine Modulates Messenger RNA Translation Efficiency , 2015, Cell.

[29]  Molly Hammell,et al.  piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis , 2015, Genes & development.

[30]  F. Ashcroft,et al.  FTO influences adipogenesis by regulating mitotic clonal expansion , 2015, Nature Communications.

[31]  Yi-Xun Liu,et al.  Regulation of spermatogonial stem cell self-renewal and spermatocyte meiosis by Sertoli cell signaling. , 2015, Reproduction.

[32]  Steven L Salzberg,et al.  HISAT: a fast spliced aligner with low memory requirements , 2015, Nature Methods.

[33]  S. Tavazoie,et al.  N6-methyladenosine marks primary microRNAs for processing , 2015, Nature.

[34]  Qi Zhou,et al.  m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency. , 2015, Cell stem cell.

[35]  Erez Y. Levanon,et al.  m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation , 2015, Science.

[36]  Sven Rahmann,et al.  N6-Adenosine Methylation in MiRNAs , 2015, PloS one.

[37]  Chuan He,et al.  N6-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions , 2015, Nature.

[38]  S. Jaffrey,et al.  A mRNA methylation directs translational control of heat shock response , 2015 .

[39]  Lan Lin,et al.  rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data , 2014, Proceedings of the National Academy of Sciences.

[40]  Chuan He,et al.  FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis , 2014, Cell Research.

[41]  M. Wilkinson,et al.  Transcriptional control of spermatogonial maintenance and differentiation. , 2014, Seminars in cell & developmental biology.

[42]  Michael Q. Zhang,et al.  HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. , 2014, Cell reports.

[43]  Yang Wang,et al.  N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells , 2014, Nature Cell Biology.

[44]  A. Mele,et al.  Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis , 2014, Nature Protocols.

[45]  Samir Adhikari,et al.  Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase , 2014, Cell Research.

[46]  Miao Yu,et al.  A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation , 2013, Nature chemical biology.

[47]  Zhike Lu,et al.  m6A-dependent regulation of messenger RNA stability , 2013, Nature.

[48]  Perturbation of m 6 A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 Sites Citation , 2014 .

[49]  Minoru Yoshida,et al.  RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock , 2013, Cell.

[50]  Arne Klungland,et al.  ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. , 2013, Molecular cell.

[51]  C. Payne,et al.  MicroRNA 146 (Mir146) Modulates Spermatogonial Differentiation by Retinoic Acid in Mice1 , 2013, Biology of reproduction.

[52]  Bing Ren,et al.  N6-methyladenosine-dependent regulation of messenger RNA stability , 2013 .

[53]  M. Kupiec,et al.  Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq , 2012, Nature.

[54]  M. Gori,et al.  SOHLH1 and SOHLH2 control Kit expression during postnatal male germ cell development , 2012, Journal of Cell Science.

[55]  A. Rajkovic,et al.  SOHLH1 and SOHLH2 coordinate spermatogonial differentiation. , 2012, Developmental biology.

[56]  Chengqi Yi,et al.  N6-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO , 2011, Nature chemical biology.

[57]  Helga Thorvaldsdóttir,et al.  Integrative Genomics Viewer , 2011, Nature Biotechnology.

[58]  J. Ule,et al.  iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution , 2010, Nature Structural &Molecular Biology.

[59]  Cole Trapnell,et al.  Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.

[60]  John C. Schimenti,et al.  Genetics of mammalian meiosis: regulation, dynamics and impact on fertility , 2010, Nature Reviews Genetics.

[61]  Richard Durbin,et al.  Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .

[62]  Brad T. Sherman,et al.  Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists , 2008, Nucleic acids research.

[63]  B. Frey,et al.  Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing , 2008, Nature Genetics.

[64]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[65]  Michael L. Creech,et al.  Integration of biological networks and gene expression data using Cytoscape , 2007, Nature Protocols.

[66]  D. Smiraglia,et al.  Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells. , 2007, Developmental biology.

[67]  D. Castrillon,et al.  Generation of a germ cell‐specific mouse transgenic Cre line, Vasa‐Cre , 2007, Genesis.

[68]  R. Feil,et al.  Differential histone modifications mark mouse imprinting control regions during spermatogenesis , 2007, The EMBO journal.

[69]  E. Wagner,et al.  Nuclear Autoantigenic Sperm Protein (NASP), a Linker Histone Chaperone That Is Required for Cell Proliferation* , 2006, Journal of Biological Chemistry.

[70]  M. Matzuk,et al.  Sohlh1 is essential for spermatogonial differentiation. , 2006, Developmental biology.

[71]  Characterization of the NASP promoter in 3T3 fibroblasts and mouse spermatogenic cells. , 2006, Gene.

[72]  T. Bestor,et al.  Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L , 2004, Nature.

[73]  G. Crooks,et al.  WebLogo: a sequence logo generator. , 2004, Genome research.

[74]  A. Inoue,et al.  Failure To Proliferate and Mitotic Arrest of CDK11p110/p58-Null Mutant Mice at the Blastocyst Stage of Embryonic Cell Development , 2004, Molecular and Cellular Biology.

[75]  Sergei Egorov,et al.  Pathway studio - the analysis and navigation of molecular networks , 2003, Bioinform..

[76]  M. O'Rand,et al.  Overexpression of the Linker Histone-binding Protein tNASP Affects Progression through the Cell Cycle* , 2003, The Journal of Biological Chemistry.

[77]  F. Rottman,et al.  Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase. , 1997, RNA.

[78]  M. Kajtár,et al.  Modified porynudeotides. VI. Properties of a synthetic DNA containing the anti-herpes agent (E)-5-(2-bromovinyI)-2′-deoxyuridine , 1982 .

[79]  Olivier Elemento,et al.  5 0 UTR m 6 A Promotes Cap-Independent Translation Graphical , 2022 .