Power and Efficiency of the TDT and Case-Control Design for Association Scans

[1]  Sagiv Shifman,et al.  The value of isolated populations , 2001, Nature Genetics.

[2]  D J Schaid,et al.  Evaluation of candidate genes in case-control studies: a statistical method to account for related subjects. , 2001, American journal of human genetics.

[3]  Pardis C Sabeti,et al.  Linkage disequilibrium in the human genome , 2001, Nature.

[4]  R. McGinnis General equations for Pt, Ps, and the power of the TDT and the affected-sib-pair test. , 2000, American journal of human genetics.

[5]  Pui-Yan Kwok,et al.  Juxtaposed regions of extensive and minimal linkage disequilibrium in human Xq25 and Xq28 , 2000, Nature Genetics.

[6]  G. Abecasis,et al.  Single nucleotide polymorphism and linkage disequilibrium within the TCR α/δ locus , 2000 .

[7]  N E Morton,et al.  Genetic epidemiology of single-nucleotide polymorphisms. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[8]  K. Roeder,et al.  Genomic Control for Association Studies , 1999, Biometrics.

[9]  J. Pritchard,et al.  Use of unlinked genetic markers to detect population stratification in association studies. , 1999, American journal of human genetics.

[10]  L. Kruglyak Prospects for whole-genome linkage disequilibrium mapping of common disease genes , 1999, Nature Genetics.

[11]  A S Whittemore,et al.  Power of association and linkage tests when the disease alleles are unobserved. , 1999, American journal of human genetics.

[12]  Momiao Xiong,et al.  The Power of Linkage Detection by the Transmission/Disequilibrium Tests , 1998, Human Heredity.

[13]  B. Müller-Myhsok,et al.  Maximum-likelihood expression of the transmission/disequilibrium test and power considerations. , 1998, American journal of human genetics.

[14]  M. Boehnke,et al.  Genetic association mapping based on discordant sib pairs: the discordant-alleles test. , 1998, American journal of human genetics.

[15]  McGinnis Re Hidden linkage: a comparison of the affected sib pair (ASP) test and transmission/disequilibrium test (TDT) , 1998 .

[16]  W. Ewens,et al.  A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. , 1998, American journal of human genetics.

[17]  N. Camp,et al.  Genomewide transmission/disequilibrium testing--consideration of the genotypic relative risks at disease loci. , 1997, American journal of human genetics.

[18]  W. Klitz,et al.  Association mapping of disease loci, by use of a pooled DNA genomic screen. , 1997, American journal of human genetics.

[19]  D. Curtis,et al.  Use of siblings as controls in case‐control association studies , 1997, Annals of human genetics.

[20]  N Risch,et al.  The Future of Genetic Studies of Complex Human Diseases , 1996, Science.

[21]  E. Lander,et al.  Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results , 1995, Nature Genetics.

[22]  W. Ewens,et al.  Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). , 1993, American journal of human genetics.

[23]  R. Lewontin,et al.  On measures of gametic disequilibrium. , 1988, Genetics.

[24]  N. Arnheim,et al.  Use of pooled DNA samples to detect linkage disequilibrium of polymorphic restriction fragments and human disease: studies of the HLA class II loci. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[25]  L R Cardon,et al.  Extent and distribution of linkage disequilibrium in three genomic regions. , 2001, American journal of human genetics.

[26]  J. Witte,et al.  Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. , 2000, American journal of human genetics.