Dual-path handheld system for cornea and retina imaging using optical coherence tomography

A dual-path handheld system is proposed for cornea and retina imaging using spectral domain optical coherence tomography. The handheld sample arm is designed to acquire two images simultaneously. Both eyes of a person can be imaged at the same time to obtain the images of the cornea of one eye and the retina of the other eye. Cornea, retina, and optic disc images are acquired with the proposed sample arm. Experimental results demonstrate the usefulness of this system for imaging of different eye segments. This system reduces the time required for imaging of the two eyes and is cost effective.

[1]  G. Gelikonov,et al.  In vivo OCT imaging of hard and soft tissue of the oral cavity. , 1998, Optics express.

[2]  Yilei Shao,et al.  Versatile optical coherence tomography for imaging the human eye , 2013, Biomedical optics express.

[3]  J. Fujimoto,et al.  In vivo retinal imaging by optical coherence tomography. , 1993, Optics letters.

[4]  Hyun-Woo Jeong,et al.  Spectral-domain OCT with dual illumination and interlaced detection for simultaneous anterior segment and retina imaging. , 2012, Optics express.

[5]  Jeehyun Kim,et al.  Depth enhancement in spectral domain optical coherence tomography using bidirectional imaging modality with a single spectrometer , 2016, Journal of biomedical optics.

[6]  Thilo Gambichler,et al.  Applications of optical coherence tomography in dermatology. , 2005, Journal of dermatological science.

[7]  N. Cho,et al.  Development of SD-OCT for Imaging the in vivo Human Tympanic Membrane , 2011 .

[8]  Ruchire Eranga Wijesinghe,et al.  Decalcification using ethylenediaminetetraacetic acid for clear microstructure imaging of cochlea through optical coherence tomography , 2016, Journal of biomedical optics.

[9]  Jeehyun Kim,et al.  In Vivo Monitoring on Growth and Spread of Gray Leaf Spot Disease in Capsicum annuum Leaf Using Spectral Domain Optical Coherence Tomography , 2016 .

[10]  J. Fujimoto,et al.  Optical Coherence Tomography , 1991 .

[11]  Jin U. Kang,et al.  Sapphire ball lens-based fiber probe for common-path optical coherence tomography and its applications in corneal and retinal imaging. , 2012, Optics letters.

[12]  Jeehyun Kim,et al.  Phase correction using programmable phase modulator (PPM) in optical coherence tomography , 2014 .

[13]  Igor Kozak,et al.  Retinal imaging using adaptive optics technology. , 2014, Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society.

[14]  Jeehyun Kim,et al.  Quantitative monitoring of laser-treated engineered skin using optical coherence tomography. , 2016, Biomedical optics express.

[15]  Jeehyun Kim,et al.  In vivo imaging of middle-ear and inner-ear microstructures of a mouse guided by SD-OCT combined with a surgical microscope. , 2014, Optics express.

[16]  Shanhui Fan,et al.  Optical coherence tomography for whole eye segment imaging. , 2012, Optics express.

[17]  Jee-Hyun Kim,et al.  Nondestructive defect inspection for LCDs using optical coherence tomography , 2011, Displays.

[18]  Jeehyun Kim,et al.  Development of Real-Time Dual-Display Handheld and Bench-Top Hybrid-Mode SD-OCTs , 2014, Sensors.

[19]  Shanhui Fan,et al.  Dual band dual focus optical coherence tomography for imaging the whole eye segment. , 2015, Biomedical optics express.

[20]  M. Doughty,et al.  Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. , 2000, Survey of ophthalmology.

[21]  Jeehyun Kim,et al.  Wavelength-Filter Based Spectral Calibrated Wave number - Linearization in 1.3 mm Spectral Domain Optical Coherence. , 2013, International journal of engineering and advanced technology.

[22]  Jeehyun Kim,et al.  Optical coherence tomography for advanced screening in the primary care office , 2014, Journal of biophotonics.

[23]  Yilei Shao,et al.  Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation , 2013, Biomedical optics express.

[24]  Jeehyun Kim,et al.  Lateral resolution enhancement using programmable phase modulator in optical coherence tomography. , 2015, Bio-medical materials and engineering.

[25]  Jeehyun Kim,et al.  Wide-field optical coherence microscopy of the mouse brain slice. , 2015, Optics letters.

[26]  Jeehyun Kim,et al.  Application of optical coherence tomography to detect Cucumber green mottle mosaic virus (CGMMV) infected cucumber seed , 2012, Horticulture, Environment, and Biotechnology.

[27]  David Williams.  Imaging single cells in the living retina , 2011, Vision Research.

[28]  Beop-Min Kim,et al.  Optically deviated focusing method based high-speed SD-OCT for in vivo retinal clinical applications , 2016 .

[29]  Nathan D. Shemonski,et al.  Addendum: Computational high-resolution optical imaging of the living human retina , 2015, Nature Photonics.

[30]  Jeehyun Kim,et al.  Ultra-Fast Displaying Spectral Domain Optical Doppler Tomography System Using a Graphics Processing Unit , 2012, Sensors.

[31]  Jeehyun Kim,et al.  Quantitative assessment of touch-screen panel by nondestructive inspection with three-dimensional real-time display optical coherence tomography , 2015 .

[32]  Heeyoung Jung,et al.  Optical Sensing Method for Screening Disease in Melon Seeds by Using Optical Coherence Tomography , 2011, Sensors.

[33]  Chen D. Lu,et al.  Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers , 2012, Biomedical optics express.

[34]  Jeehyun Kim,et al.  Full-range k-domain linearization in spectral-domain optical coherence tomography. , 2011, Applied optics.

[35]  Jeehyun Kim,et al.  Handheld Optical Coherence Tomography Scanner for Primary Care Diagnostics , 2011, IEEE Transactions on Biomedical Engineering.