Correlation of EGFR mutations with chromosomal alterations and expression of EGFR, ErbB3 and VEGF in tumor samples of lung adenocarcinoma patients.
暂无分享,去创建一个
E. C. Xu | A. Jauch | H. Dienemann | N. Reinmuth | Michael Thomas | F. Herth | P. Schnabel | E. Herpel | M. Meister | M. Granzow | H. Hoffmann | M. Steins | H. Lahm | T. Muley | S. Gottschling
[1] T. Ganz,et al. Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer. , 2008, Molecular immunology.
[2] J. Cigudosa,et al. Expression signatures in lung cancer reveal a profile for EGFR‐mutant tumours and identify selective PIK3CA overexpression by gene amplification , 2008, The Journal of pathology.
[3] E. C. Xu,et al. Mutational status of the epidermal growth factor receptor (EGFR) gene in thymomas and thymic carcinomas. , 2007, Cancer letters.
[4] H. Dienemann,et al. Molecular determinants of response to RTK‐targeting agents in nonsmall cell lung cancer , 2006, International journal of cancer.
[5] Kenji Suzuki,et al. Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma , 2006, International journal of cancer.
[6] J. D'haese,et al. Chromosomal aberrations in follicular non-Hodgkin lymphomas of Japanese patients, detected with comparative genomic hybridization and polymerase chain reaction analysis. , 2005, Cancer genetics and cytogenetics.
[7] J. Minna,et al. Epidermal growth factor receptor expression status in lung cancer correlates with its mutation. , 2005, Human pathology.
[8] B. Brandt,et al. Cytogenetic differences in breast cancer samples between German and Japanese patients , 2005, Journal of Clinical Pathology.
[9] S. Hirohashi,et al. Genetic Classification of Lung Adenocarcinoma Based on Array-Based Comparative Genomic Hybridization Analysis: Its Association with Clinicopathologic Features , 2005, Clinical Cancer Research.
[10] Mayumi Ono,et al. Activating Mutations in the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor Are Associated with Improved Survival in Gefitinib-Treated Chemorefractory Lung Adenocarcinomas , 2005, Clinical Cancer Research.
[11] Lesley Seymour,et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. , 2005, The New England journal of medicine.
[12] Renato Martins,et al. Erlotinib in previously treated non-small-cell lung cancer. , 2005, The New England journal of medicine.
[13] Elisa Rossi,et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. , 2005, Journal of the National Cancer Institute.
[14] H. Lane,et al. ERBB receptors and cancer: the complexity of targeted inhibitors , 2005, Nature Reviews Cancer.
[15] Edward S. Kim,et al. Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] Hiroyuki Sakurai,et al. Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas , 2005, Cancer.
[17] C. Mermel,et al. ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[18] A. Marchetti,et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[19] H. Varmus,et al. KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib , 2005, PLoS medicine.
[20] Michael Peyton,et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. , 2005, Cancer research.
[21] Daniel A. Haber,et al. Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways , 2004, Science.
[22] Daniel Jones. Anticancer drugs: To the rescue? , 2004, Nature Reviews Drug Discovery.
[23] Kenji Tada,et al. Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme. , 2003, Cancer research.
[24] R. Eils,et al. From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[25] M. Sliwkowski,et al. Preclinical studies with Erlotinib (Tarceva). , 2003, Seminars in oncology.
[26] L. Ellis,et al. Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells , 2003, British Journal of Cancer.
[27] F. Hirsch,et al. Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas , 2002, British Journal of Cancer.
[28] S. Petersen,et al. Chromosomal imbalances of primary and metastatic lung adenocarcinomas , 2002, The Journal of pathology.
[29] Thomas Ragg,et al. Bayesian learning and evolutionary parameter optimization , 2001, AI Commun..
[30] A. Harris,et al. Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway , 2001, British Journal of Cancer.
[31] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[32] N. Reinmuth,et al. Ploidy, expression of erbB1, erbB2, P53 and amplification of erbB1, erbB2 and erbB3 in non-small cell lung cancer. , 2000, The European respiratory journal.
[33] L. Ellis,et al. Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases , 2000, Cancer.
[34] S. Scholnick,et al. Localization of a putative tumor suppressor gene in the sub-telomeric region of chromosome 8p , 1999, Oncogene.
[35] L. Ellis,et al. The implications of angiogenesis for the biology and therapy of cancer metastasis , 1994, Cell.
[36] J Piper,et al. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors , 1994, Genes, chromosomes & cancer.
[37] Thomas Cremer,et al. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization , 1993, Human Genetics.
[38] K. Kinzler,et al. Relationship between gene amplification and chromosomal deviations in malignant human gliomas. , 1987, Cancer genetics and cytogenetics.
[39] Y. Shimosato,et al. Histological Typing of Lung Tumours 1 , 1981 .
[40] BMC Molecular Biology BioMed Central , 2008 .
[41] N. Reinmuth,et al. Prognostic significance of vessel architecture and vascular stability in non-small cell lung cancer. , 2007, Lung cancer.