Miniature telemetry system for the recording of action and field potentials

A simple miniature telemetry system for neural recording from freely moving rats is described. It weighs only 1% of the body weight of an adult rat and its recordings are devoid of artifacts due to the animal movement. Together with its long recording time (more than 38 h), its isotropic nature, which is essential for working with freely moving animals, offers further advantages. A frequency-modulation receiver with a flat frequency response down to 6 Hz has been designed for wide-spectrum recording of neural signals, allowing field potential recordings. A detailed printed-circuit layout and the lack of a trimming requirement will allow the system to be easily duplicated by other neuroscientists who are not familiar with wireless-transmission technologies.

[1]  Isao Shimoyama,et al.  A radio-telemetry system with a shape memory alloy microelectrode for neural recording of freely moving insects , 2004, IEEE Transactions on Biomedical Engineering.

[2]  Hen-Wai Tsao,et al.  A multichannel system for recording and analysis of cortical field potentials in freely moving rats , 1999, Journal of Neuroscience Methods.

[3]  Fu-Shan Jaw Optimal sampling of electrophysiological signals , 2001 .

[4]  R G Beschle,et al.  New subminiature amplifier-transmitters for telemetering biopotentials. , 1967, Electroencephalography and clinical neurophysiology.

[5]  Patrick D Wolf,et al.  A multichannel telemetry system for single unit neural recordings , 2004, Journal of Neuroscience Methods.

[6]  Lei Li,et al.  A multi-channel telemetry system for brain microstimulation in freely roaming animals , 2004, Journal of Neuroscience Methods.

[7]  Chih-Kung Lee,et al.  An implantable integrated SiGe FM transmitter for HRV biotelemetry , 2004, IEEE International Workshop on Biomedical Circuits and Systems, 2004..

[8]  P. Grohrock,et al.  Dual-channel telemetry system for recording vocalization-correlated neuronal activity in freely moving squirrel monkeys , 1997, Journal of Neuroscience Methods.

[9]  R Kanzaki,et al.  A dual-channel FM transmitter for acquisition of flight muscle activities from the freely flying hawkmoth, Agrius convolvuli , 2002, Journal of Neuroscience Methods.

[10]  Rainer Hartmann,et al.  A stimulator with wireless power and signal transmission for implantation in animal experiments and other applications , 1998, Journal of Neuroscience Methods.

[11]  Christoph Pinkwart,et al.  Miniature three-function transmitting system for single neuron recording, wireless brain stimulation and marking , 1987, Journal of Neuroscience Methods.

[12]  Chen-Tung Yen,et al.  A simple method for fabricating horizontal and vertical microwire arrays , 2003, Journal of Neuroscience Methods.

[13]  Fu-Shan Jaw,et al.  A laser micromachined probe for recording multiple field potentials in the thalamus , 2004, Journal of Neuroscience Methods.

[14]  W. Kutsch,et al.  A radiotelemetric 2-channel unit for transmission of muscle potentials during free flight of the desert locust, Schistocerca gregaria , 1996, Journal of Neuroscience Methods.

[15]  H R Skutt,et al.  A multichannel telemetry system for use in exercise physiology. , 1970, IEEE transactions on bio-medical engineering.

[16]  L. E Sundstrom,et al.  A new protocol for the transmission of physiological signals by digital telemetry , 1997, Journal of Neuroscience Methods.

[17]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[18]  John L Kubie,et al.  Telemetry system for reliable recording of action potentials from freely moving rats , 2002, Hippocampus.