Synchronous Ileal Stromal Tumor (GIST) and Colonic Adenocarcinoma

Synchronous existence of gastrointestinal stromal tumor and colonic adenocarcinoma was rarely reported. We describe an 84-year-old female presenting with abdominal pain and obstipation followed by vomiting for 3 days. There was intermittent abdominal pain of 8 months' duration. Plain abdominal film revealed marked dilatation of the intestine proximal to the descending colon. An annular tumor was radiologically and endoscopically demonstrated in the splenic flexure of the colon. Computed tomographic scans of the abdomen had an incidental finding of a 5-cm tumor mass in the ileum. After surgical resection of both tumor lesions, the colon tumor lesion was pathologically proven to be a well-differentiated adenocarcinoma (Duck's stage C2) and another tumor from the ileum showed positive reactivity to CD 117 immunohistochemical staining consisting with gastrointestinal stromal tumor. The patient was discharged on the 18th hospital day and subsequently underwent chemotherapy (Ufur containing 100 mg Tegafur and 224 mg Uracil).