Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

[1]  M. Agbaga,et al.  ELOVL4 Mutations That Cause Spinocerebellar Ataxia-34 Differentially Alter Very Long Chain Fatty Acid Biosynthesis , 2022, Journal of lipid research.

[2]  P. Bernstein,et al.  Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4-/-/bco2-/- double knockout mice. , 2021, Experimental eye research.

[3]  B. Staels,et al.  PPAR control of metabolism and cardiovascular functions , 2021, Nature Reviews Cardiology.

[4]  Jian-xing Ma,et al.  The role of peroxisome proliferator-activated receptors in healthy and diseased eyes. , 2021, Experimental eye research.

[5]  B. Ruyter,et al.  Deposition and metabolism of dietary n-3 very-long-chain PUFA in different organs of rat, mouse and Atlantic salmon , 2021, British Journal of Nutrition.

[6]  M. Ueffing,et al.  The complement system in age-related macular degeneration , 2021, Cellular and Molecular Life Sciences.

[7]  P. Bernstein,et al.  Retinal bioavailability and functional effects of a synthetic very-long-chain polyunsaturated fatty acid in mice , 2021, Proceedings of the National Academy of Sciences.

[8]  N. Bazan.  Overview of how N32 and N34 elovanoids sustain sight by protecting retinal pigment epithelial cells and photoreceptors. , 2020, Journal of lipid research.

[9]  P. Calder,et al.  Marine Omega-3 (N-3) Fatty Acids for Cardiovascular Health: An Update for 2020 , 2020, International journal of molecular sciences.

[10]  P. Subbaiah,et al.  Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: lysophosphatidylcholine is more efficient than either phosphatidylcholine or triacylglycerol. , 2019, The Journal of nutritional biochemistry.

[11]  Daniel L. Chao,et al.  The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina , 2019, bioRxiv.

[12]  M. Agbaga,et al.  Decreased very long chain polyunsaturated fatty acids in sperm correlates with sperm quantity and quality , 2019, Journal of Assisted Reproduction and Genetics.

[13]  J. Vilo,et al.  g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update) , 2019, Nucleic Acids Res..

[14]  R. Vasan,et al.  Directed Non-targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids and Related Oxylipins. , 2019, Cell chemical biology.

[15]  P. Bernstein,et al.  Supplementation with macular carotenoids improves visual performance of transgenic mice. , 2018, Archives of biochemistry and biophysics.

[16]  T. Lydic,et al.  Staphylococcus aureus Utilizes Host-Derived Lipoprotein Particles as Sources of Fatty Acids , 2018, Journal of bacteriology.

[17]  W. Gordon,et al.  Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity , 2017, Scientific Reports.

[18]  O. Kuda,et al.  Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties , 2016, Diabetes.

[19]  Lior Pachter,et al.  Near-optimal probabilistic RNA-seq quantification , 2016, Nature Biotechnology.

[20]  Shery Jacob,et al.  A simple practice guide for dose conversion between animals and human , 2016, Journal of basic and clinical pharmacy.

[21]  M. Robinson,et al.  Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences , 2015, F1000Research.

[22]  R. Yost,et al.  Comparison of blood plasma sample preparation methods for combined LC-MS lipidomics and metabolomics. , 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[23]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[24]  T. Lydic,et al.  A monophasic extraction strategy for the simultaneous lipidome analysis of polar and nonpolar retina lipids[S] , 2014, Journal of Lipid Research.

[25]  D. Bishop-Bailey,et al.  Lipid-metabolizing CYPs in the regulation and dysregulation of metabolism. , 2014, Annual review of nutrition.

[26]  P. Wong,et al.  Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid , 2014, Nature.

[27]  A. Windust,et al.  Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets , 2014, Journal of Lipid Research.

[28]  Weijun Luo,et al.  Pathview: an R/Bioconductor package for pathway-based data integration and visualization , 2013, Bioinform..

[29]  Cynthia A. Toth,et al.  Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. , 2013, JAMA.

[30]  G. Castellani,et al.  Methylation of ELOVL2 gene as a new epigenetic marker of age , 2012, Aging cell.

[31]  Y. Sauve,et al.  Dietary docosahexaenoic acid supplementation prevents age-related functional losses and A2E accumulation in the retina. , 2012, Investigative ophthalmology & visual science.

[32]  Yanhua Lin,et al.  Role of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophies , 2011, Clinical lipidology.

[33]  Yanhua Lin,et al.  Long-chain and very long-chain polyunsaturated fatty acids in ocular aging and age-related macular degeneration , 2010, Journal of Lipid Research.

[34]  D. Kelley,et al.  Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids. , 2010, The Journal of nutritional biochemistry.

[35]  Davis J. McCarthy,et al.  edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..

[36]  Sang Beom Jun,et al.  Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function , 2009, Journal of neurochemistry.

[37]  I. Rodriguez,et al.  Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process. , 2006, Molecular vision.

[38]  I. Rodriguez,et al.  Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors. , 2006, Molecular vision.

[39]  J. Sangiovanni,et al.  The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina , 2005, Progress in Retinal and Eye Research.

[40]  S. Wassall,et al.  Docosahexaenoic acid: membrane properties of a unique fatty acid. , 2003, Chemistry and physics of lipids.

[41]  R. Turner,et al.  Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man , 1985, Diabetologia.

[42]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.

[43]  J. Mesirov,et al.  The Molecular Signatures Database (MSigDB) hallmark gene set collection. , 2015, Cell systems.

[44]  Manabu T. Nakamura,et al.  Regulation of energy metabolism by long-chain fatty acids. , 2014, Progress in lipid research.

[45]  A. Poulos.  Very long chain fatty acids in higher animals—A review , 2006, Lipids.

[46]  H. Guillou,et al.  The same rat Delta6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis. , 2002, The Biochemical journal.

[47]  T. Řezanka.  Very-long-chain fatty acids from the animal and plant kingdoms. , 1989, Progress in lipid research.