Visual Inspection for Caries Detection

We aimed to perform a systematic review including a meta-analysis to evaluate the overall accuracy of visual methods for detecting carious lesions and to identify possible sources of heterogeneity among the studies included. Two reviewers searched PubMed, Embase, Scopus, and other sources through July 2014 to identify published and nonpublished studies in English. Studies of visual inspection were included that 1) assessed accuracy of the method in detecting caries lesions; 2) were performed on occlusal, proximal, or free smooth surfaces in primary or permanent teeth; 3) had a reference standard; and 4) reported sufficient data about sample size and accuracy of methods. The data were used to calculate the pooled sensitivity, specificity, diagnostic odds ratio, and summary receiver operating characteristics curve. Heterogeneity of the studies was also assessed. A total of 102 manuscripts (from 5,808 articles initially identified) and 1 abstract (from 168) met the inclusion criteria. In general, the analysis demonstrated that the visual method had good accuracy for detecting caries lesions. Although laboratory and clinical studies have presented similar accuracy, clinically obtained specificity was higher. We also observed moderate to high heterogeneity and evidence of publication bias in most papers. Moreover, studies employing widely recognized visual scoring systems presented significantly better accuracy as compared to studies that used their own criteria. In conclusion, visual caries detection method has good overall performance. Furthermore, although the identified studies had high heterogeneity and risk of bias, the use of detailed and validated indices seems to improve the accuracy of the method.

[1]  N. Pitts,et al.  In vitro validity of the Dundee Selectable Threshold Method for caries diagnosis (DSTM). , 2000, Community dentistry and oral epidemiology.

[2]  D Ricketts,et al.  Hidden caries: what is it? Does it exist? Does it matter? , 1997, International dental journal.

[3]  M. Downer Concurrent validity of an epidemiological diagnostic system for caries with the histological appearance of extracted teeth as validating criterion. , 1975, Caries research.

[4]  David Moher,et al.  Addressing Reporting Biases , 2008 .

[5]  R. Heinrich-Weltzien,et al.  Comparison of visual inspection and different radiographic methods for dentin caries detection on occlusal surfaces. , 2009, Dento maxillo facial radiology.

[6]  Patrick Bossuyt,et al.  Systematic Reviews of Diagnostic Test Accuracy , 2008, Annals of Internal Medicine.

[7]  Nigel Pitts,et al.  "ICDAS"--an international system for caries detection and assessment being developed to facilitate caries epidemiology, research and appropriate clinical management. , 2004, Community dental health.

[8]  W. Siqueira,et al.  In vitro performance of methods of approximal caries detection in primary molars. , 2009, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[9]  N B Pitts,et al.  British Association for the Study of Community Dentistry (BASCD) diagnostic criteria for caries prevalence surveys-1996/97. , 1997, Community dental health.

[10]  Mariana M Braga,et al.  Detection activity assessment and diagnosis of dental caries lesions. , 2010, Dental clinics of North America.

[11]  Constantine Gatsonis,et al.  Analysing and Presenting Results , 2010 .

[12]  D. Moher,et al.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement , 2009, BMJ : British Medical Journal.

[13]  Poul Erik Petersen,et al.  Oral Health Surveys -Basic Methods , 2013 .

[14]  E. Kidd,et al.  Reproducibility and accuracy of three methods for assessment of demineralization depth of the occlusal surface: an in vitro examination. , 1997, Caries research.

[15]  J. V. Engelshoven,et al.  Peripheral arterial disease: meta-analysis of the diagnostic performance of MR angiography. , 2000, Radiology.

[16]  A. Ismail,et al.  Visual and Visuo-tactile Detection of Dental Caries , 2004, Journal of dental research.

[17]  V. Baelum,et al.  Reliability of a New Caries Diagnostic System Differentiating between Active and Inactive Caries Lesions , 1999, Caries Research.

[18]  C. Deery,et al.  Clinical Relevance of Studies on the Accuracy of Visual Inspection for Detecting Caries Lesions: A Systematic Review , 2015, Caries Research.

[19]  A Lussi,et al.  Comparison of different methods for the diagnosis of fissure caries without cavitation. , 1993, Caries research.

[20]  T. Marthaler A standardized system of recording dental conditions. , 1966, Helvetica odontologica acta.

[21]  K. Schulz,et al.  An overview of clinical research: the lay of the land , 2002, The Lancet.

[22]  D. Moher,et al.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. , 2010, International journal of surgery.

[23]  Ann Wenzel,et al.  Implications of caries diagnostic strategies for clinical management decisions. , 2012, Community dentistry and oral epidemiology.

[24]  K V Mortimer,et al.  The relationship of deciduous enamel structure to dental disease. , 1970, Caries research.

[25]  P. Bossuyt,et al.  Empirical evidence of design-related bias in studies of diagnostic tests. , 1999, JAMA.

[26]  James D Bader,et al.  A systematic review of the performance of methods for identifying carious lesions. , 2002, Journal of public health dentistry.

[27]  R. Shellis Relationship between human enamel structure and the formation of caries-like lesions in vitro. , 1984, Archives of oral biology.

[28]  V. Clerehugh Oral health surveys: Basic methods, 3rd edition , 1989 .

[29]  Susan Mallett,et al.  QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies , 2011, Annals of Internal Medicine.

[30]  P D Bezemer,et al.  Publications on diagnostic test evaluation in family medicine journals: an optimal search strategy. , 2000, Journal of clinical epidemiology.

[31]  Peter Jüni,et al.  Direction and impact of language bias in meta-analyses of controlled trials: empirical study. , 2002, International journal of epidemiology.

[32]  M. Braga,et al.  Radiographic and Laser Fluorescence Methods Have No Benefits for Detecting Caries in Primary Teeth , 2012, Caries Research.

[33]  Downer Mc Validation of methods used in dental caries diagnosis. , 1989 .

[34]  A R Jadad,et al.  What contributions do languages other than English make on the results of meta-analyses? , 2000, Journal of clinical epidemiology.

[35]  C. Deery,et al.  Fluorescence-Based Methods for Detecting Caries Lesions: Systematic Review, Meta-Analysis and Sources of Heterogeneity , 2013, PloS one.

[36]  J. Deeks,et al.  A methodological review of how heterogeneity has been examined in systematic reviews of diagnostic test accuracy. , 2005, Health technology assessment.

[37]  N B Pitts,et al.  The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. , 2007, Community dentistry and oral epidemiology.

[38]  R. Hickel,et al.  Development, Methodology and Potential of the New Universal Visual Scoring System (UniViSS) for Caries Detection and Diagnosis , 2009, International journal of environmental research and public health.

[39]  J. Sterne,et al.  Systematic reviews of test accuracy should search a range of databases to identify primary studies. , 2008, Journal of clinical epidemiology.

[40]  M. Raadal,et al.  Diagnosis of dentin involvement in occlusal caries based on visual and radiographic examination of the teeth. , 1992, Scandinavian journal of dental research.

[41]  Patrick M M Bossuyt,et al.  Exploring sources of heterogeneity in systematic reviews of diagnostic tests , 2002, Statistics in medicine.