Blastic plasmacytoid dendritic cell neoplasm with history of myeloma and concomitant acute undifferentiated leukemia: Illustration of morphologic and immunophenotypic challenges of an emerging phenomenon

Siba El Hussein , Wei Wang, Sa A. Wang, Sanam Loghavi, Xiaoqiong Wang, Lianqun Qiu , Hong Fang, L. Jeffrey Medeiros, Phyu P. Aung, Carlos Torres Cabala, Jeffrey L. Jorgensen, Naveen Pemmaraju and Joseph D. Khoury Departments of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Dermatology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

[1]  F. Jardin,et al.  Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape , 2020, Haematologica.

[2]  M. Arcila,et al.  Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia. , 2020, Blood.

[3]  H. Meyerson,et al.  Flow Cytometry Identifies a Spectrum of Maturation in Myeloid Neoplasms Having Plasmacytoid Dendritic Cell Differentiation , 2020, Cytometry. Part B, Clinical cytometry.

[4]  Yan-rong Liu,et al.  Myeloid Neoplasms with Elevated Plasmacytoid Dendritic Cell Differentiation Reflect the Maturation Process of Dendritic Cells , 2019, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[5]  Hannah C. Beird,et al.  Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Commonly Presents in the Setting of Prior or Concomitant Hematologic Malignancies (PCHM): Patient Characteristics and Outcomes in the Rapidly Evolving Modern Targeted Therapy Era , 2019, Blood.

[6]  M. Gobbi,et al.  A Blastic Plasmacytoid Dendritic Cell Neoplasm-like Phenotype Identifies a Subgroup of NPM1-Mutated AML Patients with Worse Prognosis While Has Not Predictive Value in NPM1-Wt AML , 2018, Blood.

[7]  R. Kanagal-Shamanna,et al.  Myelodysplastic Syndromes: Laboratory Workup in the Context of New Concepts and Classification Criteria , 2018, Current Hematologic Malignancy Reports.

[8]  M. Gobbi,et al.  A blastic plasmacytoid dendritic cell neoplasm‐like phenotype identifies a subgroup of npm1‐mutated acute myeloid leukemia patients with worse prognosis , 2018, American journal of hematology.

[9]  M. Teitell,et al.  TCL1 and CLA expression in agranular CD4/CD56 hematodermic neoplasms (blastic NK-cell lymphomas) and leukemia cutis. , 2004, American journal of clinical pathology.