Impact of spatially correlated noise on neuronal firing.

We explore the impact of spatially correlated noise on neuronal firing when uncoupled Hodgkin-Huxley model neurons are subjected to a common subthreshold signal. Noise can play a positive role in optimizing neuronal behavior. Although the output signal-to-noise ratio decreases with enhanced noise correlation, both the degree of synchronization among neurons and the spike timing precision are improved. This suggests that there can exist precisely synchronized firings in the presence of correlated noise and that the nervous system can exploit temporal patterns of neural activity to convey more information than just using rate codes. The mechanisms underlying these noise-induced effects are also discussed in detail.

[1]  K Pakdaman,et al.  Response of an ensemble of noisy neuron models to a single input. , 1999, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

[2]  Spike timing precision for a neuronal array with periodic signal , 2001 .

[3]  Jianfeng Feng,et al.  Behavior of integrate-and-fire and Hodgkin-Huxley models with correlated inputs. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[4]  J. Movshon,et al.  A computational analysis of the relationship between neuronal and behavioral responses to visual motion , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[5]  Jürgen Kurths,et al.  Noise-induced synchronization and coherence resonance of a Hodgkin-Huxley model of thermally sensitive neurons. , 2003, Chaos.

[6]  F. Liu,et al.  Resonance-enhanced signal detection and transduction in the Hodgkin-Huxley neuronal systems. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[7]  Christof Koch,et al.  Temporal Precision of Spike Trains in Extrastriate Cortex of the Behaving Macaque Monkey , 1999, Neural Computation.

[8]  A Grinvald,et al.  Coherent spatiotemporal patterns of ongoing activity revealed by real-time optical imaging coupled with single-unit recording in the cat visual cortex. , 1995, Journal of neurophysiology.

[9]  H. Sompolinsky,et al.  Population coding in neuronal systems with correlated noise. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[10]  J. Kurths,et al.  Array-enhanced coherence resonance: nontrivial effects of heterogeneity and spatial independence of noise. , 2001, Physical review letters.

[11]  L. F. Abbott.  The timing game , 2001, Nature Neuroscience.

[12]  J. Movshon.  Reliability of Neuronal Responses , 2000, Neuron.

[13]  Wei Wang,et al.  Frequency sensitivity in weak signal detection , 1999 .

[14]  F Liu,et al.  Effects of correlated and independent noise on signal processing in neuronal systems. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[15]  J J Hopfield,et al.  What is a moment? "Cortical" sensory integration over a brief interval. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[16]  Wolf Singer,et al.  Time as coding space? , 1999, Current Opinion in Neurobiology.

[17]  A. Aertsen,et al.  Spike synchronization and rate modulation differentially involved in motor cortical function. , 1997, Science.

[18]  Ehud Zohary,et al.  Correlated neuronal discharge rate and its implications for psychophysical performance , 1994, Nature.

[19]  W. Newsome,et al.  The Variable Discharge of Cortical Neurons: Implications for Connectivity, Computation, and Information Coding , 1998, The Journal of Neuroscience.

[20]  W. Bair,et al.  Correlated Firing in Macaque Visual Area MT: Time Scales and Relationship to Behavior , 2001, The Journal of Neuroscience.

[21]  A. P. Georgopoulos,et al.  Variability and Correlated Noise in the Discharge of Neurons in Motor and Parietal Areas of the Primate Cortex , 1998, The Journal of Neuroscience.

[22]  A. Grinvald,et al.  Dynamics of Ongoing Activity: Explanation of the Large Variability in Evoked Cortical Responses , 1996, Science.

[23]  William R. Softky,et al.  The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[24]  A. Roskies.  The Binding Problem , 1999, Neuron.

[25]  J. Kurths,et al.  Array-Enhanced Coherence Resonance , 2001 .

[26]  David Ferster,et al.  Is Neural Noise Just a Nuisance? , 1996, Science.

[27]  G. Buzsáki,et al.  Gamma Oscillation by Synaptic Inhibition in a Hippocampal Interneuronal Network Model , 1996, The Journal of Neuroscience.

[28]  Fox,et al.  Second-order algorithm for the numerical integration of colored-noise problems. , 1991, Physical review. A, Atomic, molecular, and optical physics.

[29]  Michael Rudolph,et al.  Do Neocortical Pyramidal Neurons Display Stochastic Resonance? , 2001, Journal of Computational Neuroscience.

[30]  A. Destexhe,et al.  Correlation detection and resonance in neural systems with distributed noise sources. , 2001, Physical review letters.

[31]  Moss,et al.  Noise-Mediated Spike Timing Precision from Aperiodic Stimuli in an Array of Hodgekin-Huxley-Type Neurons. , 1996, Physical review letters.

[32]  Khashayar Pakdaman,et al.  Noise-induced transition in excitable neuron models , 2001, Biological Cybernetics.