Preparing the anatomical model for ablation of unresectable liver tumor

Introduction Nowadays the best treatment of the primary and secondary hepatic tumor is surgical resection, but only 5–15% of all patient with hepatocellular carcinoma and 20–25% of all patients with liver metastases are indicated for resection. In these cases some kind of ablation and other technique could be used. Aim To present the methodology of preparing the anatomical model for ablation of unresectable liver tumor. Material and methods The presented method is based on abdomen computed tomography (CT) dynamic examination. Three methods of segmentation are used: rolling vector for liver volume, modified Frangi filter for liver vessels, and fuzzy expert system with initial region-of-interest anisotropic filtration for liver metastases. Segmentation results are the input data for creating 3D anatomical models in the form of B-spline curves and surfaces performing the surface global interpolation algorithm. A graphical user interface for presentation and evaluation of models, presented in color against DICOM images in grayscale, is designed and implemented. Results The proposed approach was tested on 20 abdominal CT obtained from the Department of Clinical Radiology of Silesian Medical University. The lack of a “gold standard” provides for the correction of the results. Conclusions Preparation of the anatomical model is one of the important early stages of the use of image-based navigation systems. This process could not take place in a fully automatic manner and verification of the results obtained is performed by the radiologist. Using the above anatomical model in surgical workflow is presented.

[1]  Dominik Spinczyk,et al.  In vitro evaluation of stereoscopic liver surface reconstruction , 2013, Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques.

[2]  Andrew S. Glassner,et al.  Introduction to computer graphics , 2013, SIGGRAPH '13.

[3]  Gábor Székely,et al.  Predicting Liver Motion Using Exemplar Models , 2012, Abdominal Imaging.

[4]  Dominik Spinczyk,et al.  Stereoscopic liver surface reconstruction , 2012, Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques.

[5]  Xing Zhang,et al.  Interactive liver tumor segmentation from ct scans using support vector classification with watershed , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  Marcin Rudzki,et al.  Automatic image contrast enhancement method for liver vasculature detection , 2011, Proceedings of the 18th International Conference Mixed Design of Integrated Circuits and Systems - MIXDES 2011.

[7]  E. Abdalla Resection of Colorectal Liver Metastases , 2011, Journal of Gastrointestinal Surgery.

[8]  Marcin Rudzki,et al.  Automatic Liver Vasculature Segmentation Method Using a Modified Multiscale Vesselness Filter , 2011 .

[9]  P. Norton,et al.  Introduction to Computers , 2010 .

[10]  Kai Yang,et al.  Interventional navigation systems for treatment of unresectable liver tumor , 2010, Medical & Biological Engineering & Computing.

[11]  R. Elliott,et al.  Stereotactic radiofrequency ablation: a minimally invasive technique for nonpalpable breast cancer in postmenopausal patients. , 2009, Cancer epidemiology.

[12]  Daniel Rueckert,et al.  Medical Image Computing and Computer-Assisted Intervention − MICCAI 2017: 20th International Conference, Quebec City, QC, Canada, September 11-13, 2017, Proceedings, Part II , 2017, Lecture Notes in Computer Science.

[13]  K. Cleary,et al.  Image-guided interventions : technology and applications , 2008 .

[14]  Yrjö Häme Liver Tumor Segmentation Using Implicit Surface Evolution , 2008 .

[15]  Philippe L. Pereira,et al.  Actual role of radiofrequency ablation of liver metastases , 2007, European Radiology.

[16]  Makoto Hashizume,et al.  Interventional navigation for abdominal therapy based on simultaneous use of MRI and ultrasound , 2006, Medical and Biological Engineering and Computing.

[17]  Sumanta N. Pattanaik,et al.  Physiologically-based modeling and visualization of deformable lungs , 2003, 11th Pacific Conference onComputer Graphics and Applications, 2003. Proceedings..

[18]  M. Prokop,et al.  Spiral and multislice computed tomography of the body , 2003 .

[19]  C. Couinaud,et al.  Liver Anatomy: Portal (and Suprahepatic) or Biliary Segmentation , 2000, Digestive Surgery.

[20]  L. Ellis,et al.  Radiofrequency Ablation of Unresectable Primary and Metastatic Hepatic Malignancies: Results in 123 Patients , 1999 .

[21]  Alejandro F. Frangi,et al.  Muliscale Vessel Enhancement Filtering , 1998, MICCAI.

[22]  Guido Gerig,et al.  3D Multi-scale line filter for segmentation and visualization of curvilinear structures in medical images , 1997, CVRMed.

[23]  Paul Dierckx,et al.  Curve and surface fitting with splines , 1994, Monographs on numerical analysis.

[24]  Berthold K. P. Horn,et al.  Closed-form solution of absolute orientation using unit quaternions , 1987 .

[25]  J. Lundy,et al.  Liver Metastases. , 1981, Current problems in surgery.

[26]  Richard B. Bunt,et al.  An introduction to computer , 1979 .