Interspecies scaling of tolcapone, a new inhibitor of catechol-O-methyltransferase (COMT). Use of in vitro data from hepatocytes to predict metabolic clearance in animals and humans.
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D. Jaeck | J. Meyer | T. Lavé | R. C. Chou | M. Schmitt | P. Coassolo | S. Dupin | M. Kapps | B. Morgenroth | R. Chou