Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
暂无分享,去创建一个
Bernhard Kuster | Carsten Hopf | Nigel Ramsden | Marcus Bantscheff | Gerard Drewes | A. Bauer | Jens M. Rick | Sonja Bastuck | G. Drewes | M. Raida | T. Bouwmeester | B. Kuster | G. Neubauer | Markus Boesche | Christina Rau | M. Bantscheff | N. Ramsden | Toby Mathieson | D. Eberhard | C. Hopf | G. Sweetman | S. Hobson | Yann Abraham | V. Reader | U. Kruse | Sonja Bastuck | Tewis Bouwmeester | Andreas Bauer | Toby Mathieson | Gavain Sweetman | Dirk Eberhard | Gitte Neubauer | Jens Rick | Jessica Perrin | Markus Boesche | Yann Abraham | Manfred Raida | Jessica Perrin | Scott Hobson | Christina Rau | Valérie Reader | Ulrich Kruse | Christina E. Rau
[1] James D. Griffin,et al. Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia , 2007, Nature Reviews Cancer.
[2] Helge Weissig,et al. Functional interrogation of the kinome using nucleotide acyl phosphates. , 2007, Biochemistry.
[3] G. Superti-Furga,et al. Dasatinib (BMS354825) Inhibits IgE-Dependent Activation and Histamine Release in Human Blood Basophils. , 2006 .
[4] Ping Chen,et al. 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase in , 2006, Journal of medicinal chemistry.
[5] W. Vogel,et al. Discoidin domain receptor 1-deficient mice are resistant to bleomycin-induced lung fibrosis. , 2006, American journal of respiratory and critical care medicine.
[6] C. Ford,et al. Sensing extracellular matrix: an update on discoidin domain receptor function. , 2006, Cellular signalling.
[7] F. Lee,et al. Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis. , 2006, Blood.
[8] N. Gray,et al. Rational design of inhibitors that bind to inactive kinase conformations , 2006, Nature chemical biology.
[9] C·霍普夫,et al. Process for the identification of novel enzyme interacting compounds , 2006 .
[10] S. Hall,et al. Chemoproteomics-driven drug discovery: addressing high attrition rates. , 2006, Drug discovery today.
[11] T. Haystead. The purinome, a complex mix of drug and toxicity targets. , 2006, Current topics in medicinal chemistry.
[12] C. Niemeyer,et al. Effect of STI-571 (imatinib mesylate) in combination with retinoic acid and gamma-irradiation on viability of neuroblastoma cells. , 2006, Biochemical and biophysical research communications.
[13] G. Ferry,et al. NRH:quinone reductase 2: an enzyme of surprises and mysteries. , 2005, Biochemical pharmacology.
[14] A. Fliri,et al. Analysis of drug-induced effect patterns to link structure and side effects of medicines , 2005, Nature chemical biology.
[15] D. Campbell,et al. Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428. , 2005, The Biochemical journal.
[16] William Pao,et al. Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[17] Kevan M Shokat,et al. Features of selective kinase inhibitors. , 2005, Chemistry & biology.
[18] L. Wodicka,et al. A small molecule–kinase interaction map for clinical kinase inhibitors , 2005, Nature Biotechnology.
[19] I. Graef,et al. Recruitment of the Extracellular Signal-Regulated Kinase/Ribosomal S6 Kinase Signaling Pathway to the NFATc4 Transcription Activation Complex , 2005, Molecular and Cellular Biology.
[20] Ping Chen,et al. Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. , 2004, Journal of medicinal chemistry.
[21] A. Ullrich,et al. Strategies to overcome resistance to targeted protein kinase inhibitors , 2004, Nature Reviews Drug Discovery.
[22] M. Cotten,et al. Chemical Proteomic Analysis Reveals Alternative Modes of Action for Pyrido[2,3-d]pyrimidine Kinase Inhibitors* , 2004, Molecular & Cellular Proteomics.
[23] K. Parker,et al. Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents*S , 2004, Molecular & Cellular Proteomics.
[24] C. Daniels,et al. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. , 2004, The Journal of clinical investigation.
[25] Min Wu,et al. Fishing for targets: novel approaches using small molecule baits. , 2004, Drug discovery today. Technologies.
[26] D. Fabbro,et al. Structural insights into the conformational selectivity of STI-571 and related kinase inhibitors. , 2004, Current opinion in drug discovery & development.
[27] Richard Morphy,et al. From magic bullets to designed multiple ligands. , 2004, Drug discovery today.
[28] C. Heldin,et al. Suppressors of T-cell Receptor Signaling Sts-1 and Sts-2 Bind to Cbl and Inhibit Endocytosis of Receptor Tyrosine Kinases* , 2004, Journal of Biological Chemistry.
[29] Fei Ye,et al. 7-Alkoxy-4-phenylamino-3-quinolinecar-bonitriles as dual inhibitors of Src and Abl kinases. , 2004, Journal of medicinal chemistry.
[30] Oliver Hantschel,et al. Regulation of the c-Abl and Bcr–Abl tyrosine kinases , 2004, Nature Reviews Molecular Cell Biology.
[31] M. Cotten,et al. An efficient proteomics method to identify the cellular targets of protein kinase inhibitors , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[32] Peter G. Schultz,et al. Synthetic small molecules that control stem cell fate , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[33] Li Fang,et al. p53 induction and activation of DDR1 kinase counteract p53‐mediated apoptosis and influence p53 regulation through a positive feedback loop , 2003, The EMBO journal.
[34] D. Boschelli,et al. SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice. , 2003, Cancer research.
[35] T. Hunter,et al. The Protein Kinase Complement of the Human Genome , 2002, Science.
[36] Timothy A J Haystead,et al. Discovery of novel targets of quinoline drugs in the human purine binding proteome. , 2002, Molecular pharmacology.
[37] Doriano Fabbro,et al. Targeting protein kinases in cancer therapy. , 2002, Current opinion in drug discovery & development.
[38] M. Mann,et al. Large-scale Proteomic Analysis of the Human Spliceosome References , 2006 .
[39] Alex Matter,et al. Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug , 2002, Nature Reviews Drug Discovery.
[40] P. Cohen. Protein kinases — the major drug targets of the twenty-first century? , 2002, Nature reviews. Drug discovery.
[41] A. Orth,et al. Large-scale analysis of the human and mouse transcriptomes , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[42] T. Ganesan,et al. Functional analysis of discoidin domain receptor 1: effect of adhesion on DDR1 phosphorylation , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[43] T. Jacks,et al. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications , 2001, Oncogene.
[44] T. C. Jenkins,et al. Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy. , 2000, Cancer research.
[45] J Mottram,et al. Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors. , 2000, Chemistry & biology.
[46] Jürg Zimmermann,et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells , 1996, Nature Medicine.
[47] A. Shevchenko,et al. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. , 1996, Analytical chemistry.
[48] T. Meyer,et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. , 1996, Cancer research.
[49] C. Lowe,et al. Some parameters relevant to affinity chromatography on immobilized nucleotides. , 1973, The Biochemical journal.