Assessment of α-amanitin toxicity and effects of silibinin and penicillin in different in vitro models.
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[1] S. Forbes,et al. Blended electrospinning with human liver extracellular matrix for engineering new hepatic microenvironments , 2019, Scientific Reports.
[2] H. Goudarzi,et al. Silibinin upregulates E-cadherin expression in MKN-45 human gastric cancer cells , 2018 .
[3] S. Ohta,et al. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures. , 2018, Biological & pharmaceutical bulletin.
[4] J. Diaz. Amatoxin-Containing Mushroom Poisonings: Species, Toxidromes, Treatments, and Outcomes. , 2018, Wilderness & environmental medicine.
[5] U. Udomsubpayakul,et al. Clinical characteristics and outcome of toxicity from Amanita mushroom poisoning , 2017, International journal of general medicine.
[6] G. Mailhot,et al. Phosphate-Linked Silibinin Dimers (PLSd): New Promising Modified Metabolites , 2017, Molecules.
[7] Simon Messner,et al. Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury , 2017, Archives of Toxicology.
[8] Christine Unger,et al. Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT–mTOR–S6K signaling and drug responses , 2017, Journal of Cell Science.
[9] H. Faulstich,et al. Cyclopeptide-Containing Mushrooms: The Deadly Amanitas , 2017 .
[10] Kristi S Anseth,et al. Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype. , 2016, Biomaterials.
[11] E. Kaya,et al. A Case Study: What Doses of Amanita phalloides and Amatoxins Are Lethal to Humans? , 2015, Wilderness & environmental medicine.
[12] Aleksandra Galetin,et al. Meta-Analysis of Expression of Hepatic Organic Anion–Transporting Polypeptide (OATP) Transporters in Cellular Systems Relative to Human Liver Tissue , 2015, Drug Metabolism and Disposition.
[13] T. Mukohara,et al. Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer. , 2015, Oncology reports.
[14] K. Maeda. Organic anion transporting polypeptide (OATP)1B1 and OATP1B3 as important regulators of the pharmacokinetics of substrate drugs. , 2015, Biological & pharmaceutical bulletin.
[15] T. Gudermann,et al. Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells. , 2013, Chemico-biological interactions.
[16] A. Schmidt,et al. Silibinin as a potential therapeutic for sulfur mustard injuries. , 2013, Chemico-biological interactions.
[17] A. Erden,et al. Acute liver failure caused by mushroom poisoning: a case report and review of the literature , 2013, International medical case reports journal.
[18] A. Segura‐Carretero,et al. Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo , 2013, Scientific Reports.
[19] Katrin Wlcek,et al. Hepatocellular Organic Anion–Transporting Polypeptides (OATPs) and Multidrug Resistance–Associated Protein 2 (MRP2) Are Inhibited by Silibinin , 2013, Drug Metabolism and Disposition.
[20] Elmar Heinzle,et al. 3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies. , 2013, Toxicological sciences : an official journal of the Society of Toxicology.
[21] R. Agarwal,et al. Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship , 2013, PloS one.
[22] E. Hackett,et al. Milk thistle and its derivative compounds: a review of opportunities for treatment of liver disease. , 2013, Journal of veterinary internal medicine.
[23] R. Agarwal,et al. Silibinin Attenuates Sulfur Mustard Analog-Induced Skin Injury by Targeting Multiple Pathways Connecting Oxidative Stress and Inflammation , 2012, PloS one.
[24] Ralf-Torsten Pohl,et al. Legalon® SIL: The Antidote of Choice in Patients with Acute Hepatotoxicity from Amatoxin Poisoning , 2012, Current pharmaceutical biotechnology.
[25] S. Fey,et al. Determination of Drug Toxicity Using 3D Spheroids Constructed From an Immortal Human Hepatocyte Cell Line , 2012, Toxicological sciences : an official journal of the Society of Toxicology.
[26] R. Agarwal,et al. Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells , 2011, Cancer Prevention Research.
[27] J. Tavis,et al. Differential In Vitro Effects of Intravenous versus Oral Formulations of Silibinin on the HCV Life Cycle and Inflammation , 2011, PloS one.
[28] T. Sozański,et al. Influence of commonly used clinical antidotes on antioxidant systems in human hepatocyte culture intoxicated with α-amanitin , 2011, Human & experimental toxicology.
[29] P. K. Mediratta,et al. Substitute of Animals in Drug Research: An Approach Towards Fulfillment of 4R's , 2011, Indian journal of pharmaceutical sciences.
[30] I. Madubunyi. Influence of silibinin on the permeability of primary cultured cell membranes , 2012, Comparative Clinical Pathology.
[31] J. Walton,et al. Colocalization of Amanitin and a Candidate Toxin-Processing Prolyl Oligopeptidase in Amanita Basidiocarps , 2010, Eukaryotic Cell.
[32] Steven N. Hart,et al. A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues , 2010, Drug Metabolism and Disposition.
[33] Ş. Eren,et al. Mushroom poisoning: retrospective analysis of 294 cases , 2010, Clinics.
[34] S. Nyberg,et al. E-Cadherin Protects Primary Hepatocyte Spheroids from Cell Death by a Caspase-Independent Mechanism , 2009, Cell transplantation.
[35] M. Niemi,et al. Impact of OATP transporters on pharmacokinetics , 2009, British journal of pharmacology.
[36] D. Keppler,et al. Molecular characterization and inhibition of amanitin uptake into human hepatocytes. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[37] F. Panaro,et al. Liver transplantation represents the optimal treatment for fulminant hepatic failure from amanita phalloides poisoning , 2006, Transplant international : official journal of the European Society for Organ Transplantation.
[38] M. Roma,et al. Silymarin as a new hepatoprotective agent in experimental cholestasis: new possibilities for an ancient medication. , 2006, Current medicinal chemistry.
[39] L. Griffith,et al. Capturing complex 3D tissue physiology in vitro , 2006, Nature Reviews Molecular Cell Biology.
[40] Frank Stahl,et al. Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[41] S. Rapior,et al. Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis , 2002, Journal of toxicology. Clinical toxicology.