DNA secondary structures: stability and function of G-quadruplex structures
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Katrin Paeschke | Virginia A. Zakian | Matthew L. Bochman | Katrin Paeschke | V. Zakian | K. Paeschke
[1] Jean-Michel Marin,et al. Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs , 2012, Nature Structural &Molecular Biology.
[2] V. Zakian. Telomeres: the beginnings and ends of eukaryotic chromosomes. , 2012, Experimental cell research.
[3] L. Hurley,et al. Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter. , 2012, Journal of medicinal chemistry.
[4] H. Moine,et al. G‐quadruplexes in RNA biology , 2012, Wiley interdisciplinary reviews. RNA.
[5] S. Boulton,et al. RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity , 2012, Cell.
[6] S. Juranek,et al. Cell cycle regulation of G-quadruplex DNA structures at telomeres. , 2012, Current pharmaceutical design.
[7] J. Postberg,et al. A telomerase-associated RecQ protein-like helicase resolves telomeric G-quadruplex structures during replication , 2012, Gene.
[8] Zhongbo Yu,et al. Tertiary DNA structure in the single-stranded hTERT promoter fragment unfolds and refolds by parallel pathways via cooperative or sequential events. , 2012, Journal of the American Chemical Society.
[9] S. Balasubramanian,et al. 5′-UTR RNA G-quadruplexes: translation regulation and targeting , 2012, Nucleic acids research.
[10] Stephen P. Jackson,et al. Small molecule-induced DNA damage identifies alternative DNA structures in human genes , 2012, Nature chemical biology.
[11] S. Balasubramanian,et al. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA , 2011, Nucleic acids research.
[12] A. Nicolas,et al. G‐quadruplex‐induced instability during leading‐strand replication , 2011, The EMBO journal.
[13] L. Hurley,et al. Demonstration that Drug-targeted Down-regulation of MYC in Non-Hodgkins Lymphoma Is Directly Mediated through the Promoter G-quadruplex* , 2011, The Journal of Biological Chemistry.
[14] Katrin Paeschke,et al. DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase , 2011, Cell.
[15] S. Balasubramanian,et al. Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae , 2011, Nature Structural &Molecular Biology.
[16] Xuan Zhu,et al. A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation , 2011, Cell.
[17] Hong Wang,et al. Single Molecule Studies of Physiologically Relevant Telomeric Tails Reveal POT1 Mechanism for Promoting G-quadruplex Unfolding* , 2010, The Journal of Biological Chemistry.
[18] J. Sale,et al. Epigenetic Instability due to Defective Replication of Structured DNA , 2010, Molecular cell.
[19] L. Hurley,et al. The C-terminus of nucleolin promotes the formation of the c-MYC G-quadruplex and inhibits c-MYC promoter activity. , 2010, Biochemistry.
[20] F. Major,et al. RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles , 2010, Nucleic acids research.
[21] Katrin Paeschke,et al. Telomeres: Structures in need of unwinding , 2010, FEBS letters.
[22] L. Hurley,et al. Making sense of G‐quadruplex and i‐motif functions in oncogene promoters , 2010, The FEBS journal.
[23] J. Huppert,et al. Structure, location and interactions of G‐quadruplexes , 2010, The FEBS journal.
[24] C. M. Sanders. Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity. , 2010, The Biochemical journal.
[25] Jean-Louis Mergny,et al. How long is too long? Effects of loop size on G-quadruplex stability , 2010, Nucleic acids research.
[26] Mona Singh,et al. G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae , 2010, PLoS Comput. Biol..
[27] Stephen Neidle,et al. Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer , 2010, The FEBS journal.
[28] L. Hurley,et al. The c-MYC NHE III(1): function and regulation. , 2010, Annual review of pharmacology and toxicology.
[29] J. Shklover,et al. Quadruplex structures of muscle gene promoter sequences enhance in vivo MyoD-dependent gene expression , 2010, Nucleic acids research.
[30] P. Ryvkin,et al. Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential , 2009, Nucleic acids research.
[31] S. Balasubramanian,et al. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. , 2009, Journal of the American Chemical Society.
[32] S. Tavaré,et al. Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression , 2009, Nucleic acids research.
[33] L. Hurley,et al. Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands. , 2009, Journal of the American Chemical Society.
[34] Laty A. Cahoon,et al. An Alternative DNA Structure Is Necessary for Pilin Antigenic Variation in Neisseria gonorrhoeae , 2009, Science.
[35] E. Hovig,et al. The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts , 2009, Nucleic acids research.
[36] S. Neidle,et al. G-quadruplex compounds and cis-platin act synergistically to inhibit cancer cell growth in vitro and in vivo. , 2009, Biochemical pharmacology.
[37] Daekyu Sun,et al. Identification and Characterization of Nucleolin as a c-myc G-quadruplex-binding Protein* , 2009, The Journal of Biological Chemistry.
[38] Stephen Neidle,et al. The structures of quadruplex nucleic acids and their drug complexes. , 2009, Current opinion in structural biology.
[39] L. Hurley,et al. The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression. , 2009, Journal of medicinal chemistry.
[40] Jean-Louis Mergny,et al. The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo , 2009, PLoS genetics.
[41] Han Min Wong,et al. Function and targeting of G-quadruplexes. , 2009, Current opinion in molecular therapeutics.
[42] Yalin Tang,et al. Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: I. recognizing mixed G-quadruplex in human telomeres. , 2009, Chemical communications.
[43] Jaroslav Kypr,et al. Circular dichroism and conformational polymorphism of DNA , 2009, Nucleic acids research.
[44] D. Gilbert,et al. Replication timing and transcriptional control: beyond cause and effect--part II. , 2002, Current opinion in genetics & development.
[45] T. Shaikh,et al. Chromosomal instability mediated by non-B DNA: cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. , 2009, Genome research.
[46] A. Bacolla,et al. Non-B DNA structure-induced genetic instability and evolution , 2009, Cellular and Molecular Life Sciences.
[47] S. Balasubramanian,et al. FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts* , 2008, Journal of Biological Chemistry.
[48] Stephen C. West,et al. RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination , 2008, Cell.
[49] Julian Leon Huppert,et al. G-quadruplexes: the beginning and end of UTRs , 2008, Nucleic acids research.
[50] Julian Leon Huppert,et al. Four-Stranded Nucleic Acids: Structure, Function and Targeting of G-Quadruplexes , 2008 .
[51] R. Vilar,et al. Stabilisation of G-quadruplex DNA by small molecules. , 2008, Current topics in medicinal chemistry.
[52] Guliang Wang,et al. DNA triple helices: biological consequences and therapeutic potential. , 2008, Biochimie.
[53] Laurence H. Hurley,et al. Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions. , 2008, Biochimie.
[54] E. Cuppen,et al. Mutagenic Capacity of Endogenous G4 DNA Underlies Genome Instability in FANCJ-Defective C. elegans , 2008, Current Biology.
[55] Jonathan B. Chaires,et al. Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures , 2008, Nucleic acids research.
[56] H. Lipps,et al. Telomerase recruitment by the telomere end binding protein-β facilitates G-quadruplex DNA unfolding in ciliates , 2008, Nature Structural &Molecular Biology.
[57] J. Shklover,et al. Differential binding of quadruplex structures of muscle-specific genes regulatory sequences by MyoD, MRF4 and myogenin , 2008, Nucleic acids research.
[58] J. Sale,et al. PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40. , 2008, Molecular cell.
[59] Daniel Svozil,et al. DNA conformations and their sequence preferences , 2008, Nucleic acids research.
[60] K. Shin‐ya,et al. FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability , 2008, Molecular and Cellular Biology.
[61] D. Levens,et al. The functional response of upstream DNA to dynamic supercoiling in vivo , 2008, Nature Structural &Molecular Biology.
[62] Shankar Balasubramanian,et al. A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. , 2008, Biochemistry.
[63] F. Johnson,et al. Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae , 2007, Nucleic acids research.
[64] Shantanu Chowdhury,et al. QuadBase: genome-wide database of G4 DNA—occurrence and conservation in human, chimpanzee, mouse and rat promoters and 146 microbes , 2007, Nucleic Acids Res..
[65] K. Shin‐ya,et al. Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action , 2007, Proceedings of the National Academy of Sciences.
[66] P. S. Ho,et al. Phylogenomic analysis of the emergence of GC-rich transcription elements , 2007, Proceedings of the National Academy of Sciences.
[67] S. Balasubramanian,et al. Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. , 2007, Journal of the American Chemical Society.
[68] Dinshaw J. Patel,et al. Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics , 2007, Nucleic acids research.
[69] G. Ghosal,et al. The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity. , 2007, Journal of molecular biology.
[70] H. Sugiyama,et al. First International Meeting on Quadruplex DNA. , 2007, ACS chemical biology.
[71] M. Graham,et al. Telomerase recognizes G-quadruplex and linear DNA as distinct substrates. , 2007, Biochemistry.
[72] A. Rattray,et al. Hairpin- and cruciform-mediated chromosome breakage: causes and consequences in eukaryotic cells. , 2007, Frontiers in bioscience : a journal and virtual library.
[73] Shankar Balasubramanian,et al. G-quadruplexes in promoters throughout the human genome , 2006, Nucleic acids research.
[74] Sarah W. Burge,et al. Quadruplex DNA: sequence, topology and structure , 2006, Nucleic acids research.
[75] K. Shin‐ya,et al. Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia , 2006, Oncogene.
[76] B. Emanuel,et al. Palindrome-mediated chromosomal translocations in humans. , 2006, DNA repair.
[77] N. Maizels,et al. Gene function correlates with potential for G4 DNA formation in the human genome , 2006, Nucleic acids research.
[78] K. Shin‐ya,et al. The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells. , 2006, Cancer research.
[79] R. Stephens,et al. Long homopurine•homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region , 2006, Nucleic acids research.
[80] Mitali Mukerji,et al. Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation. , 2006, Genome research.
[81] G. Parkinson,et al. Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures , 2006, Nucleic acids research.
[82] T. Bryan,et al. Extension of G‐quadruplex DNA by ciliate telomerase , 2006, The EMBO journal.
[83] K. Shin‐ya,et al. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells , 2006, Oncogene.
[84] Guliang Wang,et al. Z-DNA-forming sequences generate large-scale deletions in mammalian cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[85] A. Rich,et al. Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases , 2005, Nature.
[86] Jan Postberg,et al. Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo , 2005, Nature Structural &Molecular Biology.
[87] G. Ghosal,et al. Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA , 2005, Nucleic acids research.
[88] T. Cech,et al. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[89] Raju Kucherlapati,et al. (CAG)n-hairpin DNA binds to Msh2–Msh3 and changes properties of mismatch recognition , 2005, Nature Structural &Molecular Biology.
[90] W. Wilson,et al. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure. , 2005, Journal of the American Chemical Society.
[91] Shankar Balasubramanian,et al. Prevalence of quadruplexes in the human genome , 2005, Nucleic acids research.
[92] S. Neidle,et al. Highly prevalent putative quadruplex sequence motifs in human DNA , 2005, Nucleic acids research.
[93] Jean-Louis Mergny,et al. Kinetics of tetramolecular quadruplexes , 2005, Nucleic acids research.
[94] H. Manor,et al. Abundance and degree of dispersion of genomic d(GA)n·d(TC)n sequences , 2005, Journal of Molecular Evolution.
[95] K. Shin‐ya,et al. Interaction of Telomestatin with the Telomeric Single-strand Overhang* , 2004, Journal of Biological Chemistry.
[96] P. Lou,et al. A Novel Carbazole Derivative, BMVC: a Potential Antitumor Agent and Fluorescence Marker of Cancer Cells , 2004, Chemistry & biodiversity.
[97] N. Maizels,et al. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. , 2004, Genes & development.
[98] K. Muniyappa,et al. Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets. , 2004, Nucleic acids research.
[99] J. Mergny,et al. Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing. , 2004, Nucleic acids research.
[100] N. Munshi,et al. Telomerase Inhibition and Cell Growth Arrest After Telomestatin Treatment in Multiple Myeloma , 2004, Clinical Cancer Research.
[101] J. Haber,et al. Role of Saccharomyces Single-Stranded DNA-Binding Protein RPA in the Strand Invasion Step of Double-Strand Break Repair , 2004, PLoS biology.
[102] K. Shin‐ya,et al. Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways , 2003, Oncogene.
[103] L. Hurley,et al. The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures. , 2003, Cancer research.
[104] M. A. Goldman. The role of telomeres and telomerase in cancer. , 2003, Drug discovery today.
[105] Stella Pelengaris,et al. c-MYC: more than just a matter of life and death , 2002, Nature Reviews Cancer.
[106] G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. , 2002, Nucleic acids research.
[107] D. Bearss,et al. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[108] Iris Cheung,et al. Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA , 2002, Nature Genetics.
[109] W. Lutz,et al. Regulation of N-myc expression in development and disease. , 2002, Cancer letters.
[110] Haiyong Han,et al. The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo. , 2002, Molecular cancer therapeutics.
[111] G. Evan,et al. Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression , 2002, Cell.
[112] M. Eilers,et al. Contributions of Myc to tumorigenesis. , 2002, Biochimica et biophysica acta.
[113] Kazuo Shin-Ya,et al. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. , 2002, Journal of the American Chemical Society.
[114] D. Langley,et al. Selective interactions of cationic porphyrins with G-quadruplex structures. , 2001, Journal of the American Chemical Society.
[115] I Berger,et al. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[116] Ian D. Hickson,et al. The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases , 2001, Nucleic Acids Res..
[117] Q. Wei,et al. Regulation of MyoD function in the dividing myoblast , 2001, FEBS letters.
[118] R. Cardiff,et al. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations , 2001, Nature Medicine.
[119] M. Dixon,et al. Mismatch repair blocks expansions of interrupted trinucleotide repeats in yeast. , 2000, Molecular cell.
[120] B. Byers,et al. Yeast Meiosis-Specific Protein Hop1 Binds to G4 DNA and Promotes Its Formation , 2000, Molecular and Cellular Biology.
[121] C. C. Hardin,et al. Thermodynamic and kinetic characterization of the dissociation and assembly of quadruplex nucleic acids , 2000, Biopolymers.
[122] P. Bates,et al. Antiproliferative Activity of G-rich Oligonucleotides Correlates with Protein Binding* , 1999, The Journal of Biological Chemistry.
[123] N. Maizels,et al. G4 DNA Binding by LR1 and Its Subunits, Nucleolin and hnRNP D, A Role for G-G pairing in Immunoglobulin Switch Recombination* , 1999, The Journal of Biological Chemistry.
[124] D. Gordenin,et al. Factors affecting inverted repeat stimulation of recombination and deletion in Saccharomyces cerevisiae. , 1998, Genetics.
[125] P. Pečinka,et al. DNA tetraplex formation in the control region of c-myc. , 1998, Nucleic acids research.
[126] S. Neidle,et al. Inhibition of human telomerase by a G-quadruplex-interactive compound. , 1997, Journal of medicinal chemistry.
[127] C. E. Pearson,et al. Inverted repeats, stem‐loops, and cruciforms: Significance for initiation of DNA replication , 1996, Journal of cellular biochemistry.
[128] S. Freier,et al. Kinetics of G-quartet-mediated tetramer formation. , 1996, Biochemistry.
[129] W. Gilbert,et al. The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: Implication of in vivo functions for this novel DNA structure , 1994, Cell.
[130] N. Maizels,et al. LR1 regulates c-myc transcription in B-cell lymphomas. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[131] D. Rhodes,et al. The yeast telomere‐binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA. , 1994, The EMBO journal.
[132] K. V. van Holde,et al. Unusual DNA structures, chromatin and transcription. , 1994, BioEssays : news and reviews in molecular, cellular and developmental biology.
[133] T. Cech,et al. The β subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA , 1993, Cell.
[134] G. Schroth,et al. Mapping Z-DNA in the human genome. Computer-aided mapping reveals a nonrandom distribution of potential Z-DNA-forming sequences in human genes. , 1992, The Journal of biological chemistry.
[135] A. Patel,et al. myc function and regulation. , 1992, Annual review of biochemistry.
[136] David M. Prescott,et al. Inhibition of telomerase by G-quartet DMA structures , 1991, Nature.
[137] E. Paleček,et al. Local supercoil-stabilized DNA structures. , 1991, Critical reviews in biochemistry and molecular biology.
[138] Aaron Klug,et al. Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops , 1989, Nature.
[139] T. Cech,et al. Monovalent cation-induced structure of telomeric DNA: The G-quartet model , 1989, Cell.
[140] R. Wells,et al. Stabilization of Z DNA in vivo by localized supercoiling. , 1989, Science.
[141] A. Rich,et al. The molecular structure of the left-handed Z-DNA double helix at 1.0-A atomic resolution. Geometry, conformation, and ionic interactions of d(CGCGCG). , 1989, The Journal of biological chemistry.
[142] W. Gilbert,et al. Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis , 1988, Nature.
[143] C. C. Hardin,et al. Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine·guanine base pairs , 1987, Cell.
[144] B. Glickman,et al. Structural intermediates of deletion mutagenesis: a role for palindromic DNA. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[145] F. Crick,et al. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid , 1974, Nature.
[146] D. Davies,et al. Helix formation by guanylic acid. , 1962, Proceedings of the National Academy of Sciences of the United States of America.