Statins reduce endothelial cell apoptosis via inhibition of TRAIL expression on activated CD4 T cells in acute coronary syndrome.
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[1] S. Homer-Vanniasinkam,et al. Simvastatin alters human endothelial cell adhesion molecule expression and inhibits leukocyte adhesion under flow. , 2008, Atherosclerosis.
[2] Renu Virmani,et al. Pathology of the vulnerable plaque. , 2007, Journal of the American College of Cardiology.
[3] E. Chaikof,et al. Pathogen-Sensing Plasmacytoid Dendritic Cells Stimulate Cytotoxic T-Cell Function in the Atherosclerotic Plaque Through Interferon-&agr; , 2006, Circulation.
[4] M. Böhm,et al. Rapid immunomodulation by rosuvastatin in patients with acute coronary syndrome. , 2006, European heart journal.
[5] J. Stone,et al. T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α , 2006, Nature Immunology.
[6] Kayoko Sato,et al. T Cell Recognition and Killing of Vascular Smooth Muscle Cells in Acute Coronary Syndrome , 2006, Circulation research.
[7] M. Goldstein,et al. Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin , 2006, The Journal of experimental medicine.
[8] R. Frye,et al. TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque , 2006, The Journal of experimental medicine.
[9] C. Baldari,et al. Simvastatin inhibits T‐cell activation by selectively impairing the function of Ras superfamily GTPases , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[10] M. Desnos,et al. In Vivo Induction of Endothelial Apoptosis Leads to Vessel Thrombosis and Endothelial Denudation: A Clue to the Understanding of the Mechanisms of Thrombotic Plaque Erosion , 2004, Circulation.
[11] Qingbo Xu,et al. Heat-Shock Protein 60-Reactive CD4+CD28null T Cells in Patients With Acute Coronary Syndromes , 2004, Circulation.
[12] T. Toyo-Oka,et al. Inhibition of Hydroxymethylglutaryl-Coenzyme A Reductase Reduces Th1 Development and Promotes Th2 Development , 2003, Circulation research.
[13] D. Cantrell. GTPases and T cell activation , 2003, Immunological reviews.
[14] B. Binder,et al. Simvastatin Reduces the Expression of Adhesion Molecules in Circulating Monocytes From Hypercholesterolemic Patients , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[15] S. Youssef,et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease , 2002, Nature.
[16] R. Frye,et al. T-Cell–Mediated Lysis of Endothelial Cells in Acute Coronary Syndromes , 2002, Circulation.
[17] R. Virmani,et al. The thin-cap fibroatheroma: a type of vulnerable plaque: The major precursor lesion to acute coronary syndromes , 2001, Current opinion in cardiology.
[18] F. Mach,et al. Statins as a newly recognized type of immunomodulator , 2000, Nature Medicine.
[19] M. Deckert,et al. Vav modulation of the Ras / MEK / ERK signaling pathway plays a role in NFAT activation and CD69 up‐regulation , 2000, European journal of immunology.
[20] K. Okumura,et al. Type I Interferons (IFNs) Regulate Tumor Necrosis Factor–related Apoptosis-inducing Ligand (TRAIL) Expression on Human T Cells: A Novel Mechanism for the Antitumor Effects of Type I IFNs , 1999, The Journal of experimental medicine.
[21] J. Tschopp,et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. , 1997, Immunity.
[22] R J Hohl,et al. Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras. , 1996, Blood.
[23] G. Hansson,et al. Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice. , 1996, The American journal of pathology.
[24] C A Smith,et al. Identification and characterization of a new member of the TNF family that induces apoptosis. , 1995, Immunity.
[25] S. Young,et al. Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[26] J. Witztum,et al. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[27] A. Becker,et al. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. , 1994, Circulation.
[28] G. Hansson,et al. Detection of activated T lymphocytes in the human atherosclerotic plaque. , 1989, The American journal of pathology.