Linear and cyclic peptides as substrates for Lyn tyrosine kinase

Two Tyr residues are supposed to play a crucial role in the regulation of protein tyrosine kinases of the Src family. Autophosphorylation of Src Tyr416 correlates with enzyme activation, while phosphorylation of C‐terminal Tyr527 by Csk gives rise to inactive forms of Src kinases.

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