Influence of tissue mechanical strength during UV and IR laser ablation in vitro

It has been established that the infrared (Ho:YAG at 2.09 micrometers ) ablation process involves direct heating of tissue water followed by subsurface pressure build up that ultimately leads to a violent explosion. Recently, we presented evidence that the same mechanism plays a role in ultraviolet (XeCl at 308 nm) ablation. It is expected that this process is dependent upon the mechanical strength of the irradiated tissue. A qualitative study was done to demonstrate the effect of the tissue mechanical properties on the pulsed laser ablation process and resulting mechanical damage to tissue.

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