Physiological Activation in Patients With Sleep State Misperception

Objective Sleep State Misperception insomnia has been commonly viewed as a perceptual or psychological problem. It was hypothesized that Sleep State Misperception insomnia, like psychophysiological insomnia, could be associated with increased physiological activation, here indexed by whole body metabolic rate. Method Groups of nine patients with Sleep State Misperception insomnia and age-, sex-, and weight-matched normal sleepers were evaluated on sleep, performance, mood, personality, and metabolic measures over a 36-hour sleep laboratory stay. Results Sleep State Misperception insomniacs had a subjective history of poor sleep and perceived their laboratory sleep as poor but had electroencephalogram (EEG) parameters that did not differ statistically from matched normal controls. Sleep State Misperception insomniacs had abnormal MMPI values and were subjectively more confused, tense, depressed, and angry than matched normals. Sleep State Misperception insomniacs also had a significantly increased 24-hour metabolic rate, compared with matched normals. Conclusions The overall increase in whole body oxygen use was less than that seen in psychophysiological insomniacs but was consistent with the view that Sleep State Misperception insomnia may be a mild version or a precursor to psychophysiological insomnia.

[1]  M. Bonnet,et al.  Impact of the level of physiological arousal on estimates of sleep latency. , 1994 .

[2]  T. Coates,et al.  Cognitive activity, sleep disturbance, and stage specific differences between recorded and reported sleep. , 1983, Psychophysiology.

[3]  R. Freedman,et al.  Physiological and psychological factors in sleep-onset insomnia. , 1982, Journal of abnormal psychology.

[4]  R. Freedman,et al.  EEG power spectra in sleep-onset insomnia. , 1986, Electroencephalography and clinical neurophysiology.

[5]  I. Oswald,et al.  Physiological and psychological differences between good and poor sleepers. , 1986, Journal of psychiatric research.

[6]  Harold L. Williams,et al.  Some Effects of Sleep Loss on Memory , 1966, Perceptual and motor skills.

[7]  D. Schneider-Helmert,et al.  Twenty-four-hour sleep-wake function and personality patterns in chronic insomniacs and healthy controls. , 1986, Sleep.

[8]  T. Roth,et al.  Long-term study of the sleep of insomnia patients with sleep state misperception and other insomnia patients. , 1992, The American journal of psychiatry.

[9]  E. Wolpert.  A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. , 1969 .

[10]  E. Bixler,et al.  Biopsychobehavioral Correlates of Insomnia. II. Pattern Specificity and Consistency with the Minnesota Multiphasic Personality Inventory , 1983, Psychosomatic medicine.

[11]  J. Trinder.  Subjective insomnia without objective findings: a pseudo diagnostic classification? , 1988, Psychological bulletin.

[12]  L. J. Monroe.  Psychological and physiological differences between good and poor sleepers. , 1967, Journal of abnormal psychology.

[13]  T. Roth,et al.  Daytime alertness in patients with chronic insomnia compared with asymptomatic control subjects. , 1988, Sleep.

[14]  E. Bixler,et al.  Biopsychobehavioral correlates of insomnia, V: Clinical characteristics and behavioral correlates. , 1984, The American journal of psychiatry.

[15]  M. Bonnet,et al.  24-Hour metabolic rate in insomniacs and matched normal sleepers. , 1995, Sleep.

[16]  M. Bonnet,et al.  The consequences of a week of insomnia. , 1996, Sleep.

[17]  M. Bonnet,et al.  Caffeine use as a model of acute and chronic insomnia. , 1992, Sleep.

[18]  D. Wechsler.  Manual for the Wechsler Adult Intelligence Scale. , 1955 .

[19]  S. Haynes,et al.  Insomnia: sleep patterns and anxiety level. , 1974, Journal of psychosomatic research.

[20]  P Knauth,et al.  The effect of memory load on the circadian variation in performance efficiency under a rapidly rotating shift system. , 1976, Ergonomics.