Developing automated analytical methods for scientific environments using LabVIEW.

The development of new analytical techniques often requires the building of specially designed devices, each requiring its own dedicated control software. Especially in the research and development phase, LabVIEW has proven to be one highly useful tool for developing this software. Yet, it is still common practice to develop individual solutions for different instruments. In contrast to this, we present here a single LabVIEW-based program that can be directly applied to various analytical tasks without having to change the program code. Driven by a set of simple script commands, it can control a whole range of instruments, from valves and pumps to full-scale spectrometers. Fluid sample (pre-)treatment and separation procedures can thus be flexibly coupled to a wide range of analytical detection methods. Here, the capabilities of the program have been demonstrated by using it for the control of both a sequential injection analysis - capillary electrophoresis (SIA-CE) system with UV detection, and an analytical setup for studying the inhibition of enzymatic reactions using a SIA system with FTIR detection.

[1]  Udo Weimar,et al.  LabView™ for sensor data acquisition , 1999 .

[2]  P. Worsfold,et al.  Automatic Sampler Coupled with Flow Injection‐Chemiluminescence Detection to Monitor Particle/Natural Water Interactions , 2007 .

[3]  S. Chalk,et al.  Development of the continuously variable volume reactor for flow injection analysis: Part 1. Design, capabilities and testing , 2002 .

[4]  Louis Scampavia,et al.  Micro sequential injection: automated insulin derivatization and separation using a lab-on-valve capillary electrophoresis system. , 2003, The Analyst.

[5]  A. Voulgaropoulos,et al.  Coupling of sequential injection analysis and capillary electrophoresis - Laser-induced fluorescence via a valve interface for on-line derivatization and analysis of amino acids and peptides. , 2006, Journal of chromatography. A.

[6]  P. Haris,et al.  Measuring enzymatic activity of a recombinant amidase using Fourier transform infrared spectroscopy. , 2003, Analytical biochemistry.

[7]  B. Lendl,et al.  Determination of enzyme activity inhibition by FTIR spectroscopy on the example of fructose bisphosphatase , 2009, Analytical and bioanalytical chemistry.

[8]  A. Voulgaropoulos,et al.  Automated sample treatment by flow techniques prior to liquid-phase separations. , 2007, Journal of biochemical and biophysical methods.

[9]  T. D. Walsh,et al.  LABVIEW graphical user interface for precision multichannel alignment of Raman lidar at Jet Propulsion Laboratory, Table Mountain Facility. , 2008, The Review of scientific instruments.

[10]  B. Lendl,et al.  A Mid-Infrared Flow-Through Sensor for Label-Free Monitoring of Enzyme Inhibition , 2008, Applied spectroscopy.

[11]  B. Lendl,et al.  A mid-IR flow-through sensor for direct monitoring of enzyme catalysed reactions. Case study: Measurement of carbohydrates in beer. , 2002, The Analyst.

[12]  B. Lendl,et al.  Automated sample preparation and analysis using a sequential-injection-capillary electrophoresis (SI-CE) interface. , 2006, The Analyst.

[13]  E. Achterberg,et al.  Automation of a flow injection system for the determination of dissolved silver at picomolar concentrations in seawater with inductively coupled plasma mass spectrometry , 2003, Journal of automated methods & management in chemistry.

[14]  Claire E. Lenehan,et al.  Design of LabVIEW®-based software for the control of sequential injection analysis instrumentation for the determination of morphine , 2002, Journal of automated methods & management in chemistry.