Optical Coherence Tomography: Future Applications in Cerebrovascular Imaging.

Cross-sectional imaging of biological tissue microstructure using optical backscattering was first demonstrated in 1991.1 The technique, known as optical coherence tomography (OCT), uses low-coherence interferometry to produce a 2-dimensional image of optical scattering from tissues in a way that resembles pulse-echo imaging in ultrasound. Huang et al1 revealed promising clinical and research applications with their in vitro demonstrations of this novel imaging technique in both the peripapillary area of the retina and the coronary arteries. The first in vivo clinical application of OCT was reported in 1993, when it permitted detailed, noninvasive imaging of the anterior eye chamber, as well as other structures, such as the fovea and the optic disc of the retina.2–5 Collaboration between this pioneering group and the New England Eye Center has led to its routine use in ophthalmologic diagnostics and its subsequent commercial availability in 1996.6 Recent advancements in OCT technology have broadened its application to retinal vasculature and nontransparent tissues.7–10 OCT angiography has permitted noninvasive evaluation of retinal vascular abnormalities ranging from detecting neovascularization to quantifying ischemia.11 OCT use in areas ranging from developmental biology research to clinical applications in the fields of gastroenterology, urology, and neurosurgery have now been investigated.8,12–23 Optimization of OCT technology as an imaging modality has been achieved with the use of real-time imaging yielding greater image acquisition rates and laser light sources, which have improved image resolution.12,24–27 The recent US Food and Drug Administration approval of OCT for intravascular imaging has provided an unprecedented level of detail, on the micron level, in the evaluation of vascular pathologies that involve individual vessel wall layers.28 This has also sparked interest in the translation of the technology into the field of …

[1]  C. Durst,et al.  Venous sinus stenting for reduction of intracranial pressure in IIH: a prospective pilot study. , 2017, Journal of neurosurgery.

[2]  S. Vedantham,et al.  Acute thrombus formation on phosphorilcholine surface modified flow diverters , 2017, Journal of NeuroInterventional Surgery.

[3]  D. Lopes,et al.  Analysis of neointima development in flow diverters using optical coherence tomography imaging , 2017, Journal of NeuroInterventional Surgery.

[4]  D. Ding,et al.  A pilot study and novel angiographic classification for superior sagittal sinus stenting in patients with non-thrombotic intracranial venous occlusive disease , 2017, Journal of NeuroInterventional Surgery.

[5]  Ching-Jen Chen,et al.  Patency of the vein of Labbé after venous stenting of the transverse and sigmoid sinuses , 2017, Journal of NeuroInterventional Surgery.

[6]  L. Wilkins.  Endovascular vs medical management of acute ischemic stroke , 2016, Neurology.

[7]  A. Demchuk,et al.  Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials , 2016, The Lancet.

[8]  Sylvia Glaßer,et al.  Experimental investigation of intravascular OCT for imaging of intracranial aneurysms , 2016, International Journal of Computer Assisted Radiology and Surgery.

[9]  K. van der Marel,et al.  Grading of Regional Apposition after Flow-Diverter Treatment (GRAFT): a comparative evaluation of VasoCT and intravascular OCT , 2015, Journal of NeuroInterventional Surgery.

[10]  H. Diener,et al.  Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. , 2015, The New England journal of medicine.

[11]  C. Durst,et al.  Endovascular Treatment of Venous Sinus Stenosis in Idiopathic Intracranial Hypertension: Complications, Neurological Outcomes, and Radiographic Results , 2015, TheScientificWorldJournal.

[12]  David J. Wilson,et al.  Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye , 2015, Proceedings of the National Academy of Sciences.

[13]  M. Krause,et al.  Endovascular therapy for ischemic stroke with perfusion-imaging selection. , 2015, The New England journal of medicine.

[14]  Hester F. Lingsma,et al.  A randomized trial of intraarterial treatment for acute ischemic stroke. , 2015, The New England journal of medicine.

[15]  David M Hasan,et al.  Technology developments in endovascular treatment of intracranial aneurysms , 2014, Journal of NeuroInterventional Surgery.

[16]  Hiram G Bezerra,et al.  Optical coherence tomography of the intracranial vasculature and Wingspan stent in a patient , 2014, BMJ Case Reports.

[17]  Prashant Kaul,et al.  Intra-Coronary Imaging Modalities , 2014, Current Treatment Options in Cardiovascular Medicine.

[18]  I. Meredith,et al.  Identification of concomitant ruptured plaque and intracoronary thrombus by optical coherence tomography , 2014, The Lancet.

[19]  Bo Yu,et al.  OCT compared with IVUS in a coronary lesion assessment: the OPUS-CLASS study. , 2013, JACC. Cardiovascular imaging.

[20]  H. Bezerra,et al.  Frequency-domain optical coherence tomography assessment of very late vascular response after carotid stent implantation. , 2013, Journal of vascular surgery.

[21]  David F. Kallmes,et al.  Endovascular Treatment of Intracranial Aneurysms With Flow Diverters: A Meta-Analysis , 2013, Stroke.

[22]  Hiram G Bezerra,et al.  Novel use of optical coherence tomography , 2012, Journal of NeuroInterventional Surgery.

[23]  H. Bezerra,et al.  Intravascular Frequency-Domain Optical Coherence Tomography Assessment of Atherosclerosis and Stent-Vessel Interactions in Human Carotid Arteries , 2012, American Journal of Neuroradiology.

[24]  D. Lopes,et al.  Evaluation of cerebral artery perforators and the pipeline embolization device using optical coherence tomography , 2011, Journal of NeuroInterventional Surgery.

[25]  David F Kallmes,et al.  Flow Diversion for Intracranial Aneurysms: A Review , 2011, Stroke.

[26]  Jianping Su,et al.  Neuroendovascular Optical Coherence Tomography Imaging and Histological Analysis , 2011, Neurosurgery.

[27]  T. Gambichler,et al.  Optical coherence tomography in dermatology: technical and clinical aspects , 2011, Archives of Dermatological Research.

[28]  Dimitrios Nikas,et al.  Preliminary experience with optical coherence tomography imaging to evaluate carotid artery stents: safety, feasibility and techniques. , 2011, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[29]  Toru Iwama,et al.  Demonstration of Intraluminal Thrombus in the Carotid Artery by Optical Coherence Tomography: Technical Case Report , 2010, Neurosurgery.

[30]  A. Rollins,et al.  Intracoronary optical coherence tomography: a comprehensive review clinical and research applications. , 2009, JACC. Cardiovascular interventions.

[31]  Zhongping Chen,et al.  Imaging treated brain aneurysms in vivo using optical coherence tomography , 2008, SPIE BiOS.

[32]  David Huang,et al.  Optical coherence tomography: a new method to assess aneurysm healing. , 2005, Journal of neurosurgery.

[33]  A. Molyneux.  International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial , 2002, The Lancet.

[34]  J. Fujimoto,et al.  In vivo ultrahigh-resolution optical coherence tomography. , 1999, Optics letters.

[35]  S A Boppart,et al.  Optical coherence tomography for neurosurgical imaging of human intracortical melanoma. , 1998, Neurosurgery.

[36]  J. Fujimoto,et al.  Intraoperative assessment of microsurgery with three-dimensional optical coherence tomography. , 1998, Radiology.

[37]  J. G. Fujimoto,et al.  Optical Biopsy in Human Pancreatobiliary Tissue Using Optical Coherence Tomography , 1998, Digestive Diseases and Sciences.

[38]  J. Izatt,et al.  High-resolution cross-sectional imaging of the gastrointestinal tract using optical coherence tomography: preliminary results. , 1998, Gastrointestinal endoscopy.

[39]  J. Fujimoto,et al.  High resolution imaging of the upper respiratory tract with optical coherence tomography: a feasibility study. , 1998, American journal of respiratory and critical care medicine.

[40]  J. Fujimoto,et al.  High-speed phase- and group-delay scanning with a grating-based phase control delay line. , 1997, Optics letters.

[41]  B E Bouma,et al.  Optical biopsy in human gastrointestinal tissue using optical coherence tomography. , 1997, The American journal of gastroenterology.

[42]  E A Swanson,et al.  Optical biopsy with optical coherence tomography: feasibility for surgical diagnostics. , 1997, The Journal of surgical research.

[43]  J. Fujimoto,et al.  In vivo endoscopic optical biopsy with optical coherence tomography. , 1997, Science.

[44]  J. Fujimoto,et al.  Optical biopsy in human urologic tissue using optical coherence tomography. , 1997, The Journal of urology.

[45]  J. Fujimoto,et al.  Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[46]  Stephen A. Boppart,et al.  Imaging developing neural morphology using optical coherence tomography , 1996, Journal of Neuroscience Methods.

[47]  B E Bouma,et al.  Rapid acquisition of in vivo biological images by use of optical coherence tomography. , 1996, Optics letters.

[48]  J. Fujimoto,et al.  Investigation of developing embryonic morphology using optical coherence tomography. , 1996, Developmental biology.

[49]  J. Fujimoto,et al.  Optical coherence tomography for optical biopsy. Properties and demonstration of vascular pathology. , 1996, Circulation.

[50]  J G Fujimoto,et al.  High-resolution optical coherence tomographic imaging using a mode-locked Ti:Al(2)O(3) laser source. , 1995, Optics letters.

[51]  J. Duker,et al.  Imaging of macular diseases with optical coherence tomography. , 1995, Ophthalmology.

[52]  E A Swanson,et al.  Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography. , 1994, Archives of ophthalmology.

[53]  J. Schmitt,et al.  Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering. , 1994, Physics in medicine and biology.

[54]  J. Fujimoto,et al.  In vivo retinal imaging by optical coherence tomography. , 1993, Optics letters.

[55]  A. Fercher,et al.  In vivo optical coherence tomography. , 1993, American journal of ophthalmology.

[56]  Eiji Toyota,et al.  Assessment of coronary arterial thrombus by optical coherence tomography. , 2006, The American journal of cardiology.

[57]  J. Fujimoto,et al.  Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. , 2000, Neoplasia.

[58]  G. Ripandelli,et al.  Optical coherence tomography. , 1998, Seminars in ophthalmology.

[59]  J. Fujimoto,et al.  Optical biopsy and imaging using optical coherence tomography , 1995, Nature Medicine.