Towards integrated devices for computer screen photo-assisted multi-parameter sensing.

The computer screen photo-assisted technique (CSPT) utilizes consumer electronic devices such as computer screens and web cameras for distributed chemical sensing. Key to this method is the development of small and disposable sensing assays able to aid the CSPT optical detection, and the evaluation of multiple indicators. Here we demonstrate CSPT identification of fluorescent indicators from individual 100 microm SU-8 (10) pillars covering an area of 4 mm x 4 mm with a density of 47 elements mm(-2). The extraction of distinctive spectral fingerprints is aided by the exploitation of a three-band Moiré interference that enables the partial Bayer decoding of the CSPT images.

[1]  C Di Natale,et al.  Electronic nose analysis of urine samples containing blood. , 1999, Physiological measurement.

[2]  George R. Thoma,et al.  Research Paper: Using Wireless Handheld Computers to Seek Information at the Point of Care: An Evaluation by Clinicians , 2007, J. Am. Medical Informatics Assoc..

[3]  Kazuo Arakawa,et al.  Experimental analysis of thermal displacement and strain distributions in a small outline J-leaded electronic package by using wedged-glass phase-shifting moiré interferometry , 2008 .

[4]  Wesley E. Snyder,et al.  Demosaicking methods for Bayer color arrays , 2002, J. Electronic Imaging.

[5]  Daniel Filippini,et al.  Fingerprinting of fluorescent substances for diagnostic purposes using computer screen illumination , 2005 .

[6]  Daniel Filippini,et al.  Optical properties of microstructures for computer screen photoassisted experiments , 2006 .

[7]  R. Paolesse,et al.  Polychromatic fingerprinting of excitation emission matrices. , 2008, Chemistry.

[8]  Daniel Filippini,et al.  Computer screen as a programmable light source for visible absorption characterization of (bio)chemical assays. , 2003, Chemical communications.

[9]  Philip Huie,et al.  Building thick photoresist structures from the bottom up , 2003 .

[10]  Radoslaw Mazurczyk,et al.  A novel concept of the integrated fluorescence detection system and its application in a lab-on-a-chip microdevice , 2006 .

[11]  William R. Hruschka,et al.  Computerized analysis of two-dimensional electrophoretograms , 1983 .

[12]  Gwo-Bin Lee,et al.  An integrated microfluidic chip for DNA/RNA amplification, electrophoresis separation and on‐line optical detection , 2006, Electrophoresis.

[13]  Neal A. Rakow,et al.  A colorimetric sensor array for odour visualization , 2000, Nature.

[14]  D Filippini,et al.  Measurement strategy and instrumental performance of a computer screen photo-assisted technique for the evaluation of a multi-parameter colorimetric test strip. , 2006, The Analyst.

[15]  Roger Guilard,et al.  The porphyrin handbook , 2002 .

[16]  Radislav A Potyrailo,et al.  Analog signal acquisition from computer optical disk drives for quantitative chemical sensing. , 2006, Analytical chemistry.

[17]  Daniel Filippini,et al.  Computer screen photo-assisted detection of complementary DNA strands using a luminescent zwitterionic polythiophene derivative , 2006 .

[18]  J. Gardner,et al.  Non-destructive egg freshness determination : an electronic nose based approach , 2003 .

[19]  Richard A. Johnson,et al.  Applied Multivariate Statistical Analysis , 1983 .

[20]  Daniel Filippini,et al.  Chemical sensing with familiar devices. , 2006, Angewandte Chemie.

[21]  Thomas Ruckstuhl,et al.  Supercritical angle fluorescence (SAF) microscopy. , 2004, Optics express.

[22]  W. Lukosz,et al.  Light emission by magnetic and electric dipoles close to a plane dielectric interface. II. Radiation patterns of perpendicular oriented dipoles , 1977 .

[23]  W. Lukosz,et al.  Light emission by magnetic and electric dipoles close to a plane interface. I. Total radiated power , 1977 .

[24]  Colin B. Kennedy,et al.  Automated Lab-on-a-Chip Analysis of DNA Fragments , 2001 .

[25]  C. Mirkin,et al.  Scanometric DNA array detection with nanoparticle probes. , 2000, Science.