A time-domain diffuse optical/fluorescent tomography using multi-dimensional TCSPC design

Techniques of time-correlated single-photon counting (TCSPC) have been widely used in diffuse optical tomography (DOT) and diffuse fluorescence tomography (DFT). While a multi-channel TCSPC-based DOT/DFT system can be conveniently constructed using independent modules, the state-of-the-art TCSPC technique has extended its multidimensional function by facilitating a compact and cost-effective design of the multi-channel as well as multi-wavelength data-acquisition. We herein present a revised multi-channel TCSPC system that is based the multidimensional function of the TCSPC device. We also design a series of DOT and DFT experiments to validate effectiveness of the system.