A 70-$\mu$ m Pitch 8-$\mu$ W Self-Biased Charge-Integration Active Pixel for Digital Mammography

This paper presents a new low-power compact CMOS active pixel circuit specifically optimized for full-field digital mammography. The proposed digital pixel sensor (DPS) architecture includes self-bias capability at ±10% accuracy, up to 15 nA of dark-current autocalibration, built-in test mechanisms, selectable e-/h+ collection, 10-b lossless charge-integration analog-to-digital conversion, more than 1 decade of individual gain tuning for fixed pattern noise cancellation, and a 50-Mb/s digital-only input/output interface. Experimental results for a 70-μm pitch 8-μW DPS cell example are reported in 0.18-μm CMOS 1-polySi 6-metal technology.

[1]  F. Serra-Graells,et al.  A 0.18µm CMOS low-power charge-integration DPS for X-ray imaging , 2009, 2009 IEEE Biomedical Circuits and Systems Conference.

[2]  Michael Campbell,et al.  Medipix3: A 64 k pixel detector readout chip working in single photon counting mode with improved spectrometric performance , 2011 .

[3]  R. Dinapoli,et al.  Medipix2: A 64-k pixel readout chip with 55-/spl mu/m square elements working in single photon counting mode , 2001 .

[4]  C. D'Orsi,et al.  Diagnostic Performance of Digital versus Film Mammography for Breast-Cancer Screening , 2006 .

[5]  Francisco Serra-Graells,et al.  Sub-1-V CMOS proportional-to-absolute temperature references , 2003, IEEE J. Solid State Circuits.

[6]  G. Meddeler,et al.  A Readout Chip for a 64 x 64 Pixel Matrix with 15-bit Single Photon Counting* , 1997 .

[7]  Leif Gustafsson,et al.  Performance of a chip for hybrid pixel detectors with two counters for X-ray imaging , 2004 .

[8]  R. Horisberger,et al.  Development of single photon counting detectors at the Swiss Light Source , 2004 .

[9]  T. Takahashi,et al.  Single photon counting X-ray imaging with Si and CdTe single chip pixel detectors and multichip pixel modules , 2004, IEEE Transactions on Nuclear Science.

[10]  K. Fujita,et al.  High resolution large formatted CMOS flat panel sensors for X-ray , 2003, 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515).

[11]  Timothy J Wilt,et al.  Screening for breast cancer: U.S. Preventive Services Task Force recommendation statement. , 2009, Annals of internal medicine.

[12]  Gabor C. Temes,et al.  Oversampling delta-sigma data converters : theory, design, and simulation , 1992 .

[13]  G. Pellegrini,et al.  Performance limits of a 55-/spl mu/m pixel CdTe detector , 2006, IEEE Transactions on Nuclear Science.

[14]  P. Pangaud,et al.  XPAD: pixel detector for material sciences , 2005 .

[15]  Mohan Doss,et al.  PEM-2400 - a biopsy-ready PEM scanner with real-time X-ray correlation capability , 2002, 2002 IEEE Nuclear Science Symposium Conference Record.

[16]  N. Petrick,et al.  Digital mammography: observer performance study of the effects of pixel size on the characterization of malignant and benign microcalcifications. , 2001, Academic radiology.

[17]  E. Culurciello,et al.  A biomorphic digital image sensor , 2003, IEEE J. Solid State Circuits.

[18]  W. Davros Medical Imaging Principles, Detectors, and Electronics , 2009 .

[19]  G. Pellegrini,et al.  Performance Limits of a 55- m Pixel CdTe Detector , 2004 .

[20]  Timothy J Wilt,et al.  Screening for breast cancer: U.S. Preventive Services Task Force recommendation statement. , 2009, Annals of internal medicine.

[21]  E. Vittoz,et al.  An analytical MOS transistor model valid in all regions of operation and dedicated to low-voltage and low-current applications , 1995 .

[22]  Francisco Serra-Graells,et al.  A novel DPS integrator for fast CMOS imagers , 2008, 2008 IEEE International Symposium on Circuits and Systems.