Enantioselective, Palladium-Catalyzed Conjugate Additions of Arylboronic Acids to Form Bis-benzylic Quaternary Stereocenters.
暂无分享,去创建一个
[1] B. Stoltz,et al. Preparation of (S)-tert-ButylPyOx and Palladium-catalyzed Asymmetric Conjugate Addition of Arylboronic Acids. , 2016, Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals.
[2] C. Ottmann,et al. Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation. , 2016, Journal of medicinal chemistry.
[3] B. Stoltz,et al. Synthesis of diverse β-quaternary ketones via palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enones. , 2015, Tetrahedron.
[4] B. Stoltz,et al. Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles. , 2015, Organic process research & development.
[5] R. Zeeland,et al. Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β,β-Disubstituted Enones in Aqueous Media: Formation of Bis-benzylic and ortho-Substituted Benzylic Quaternary Centers , 2015 .
[6] B. Stoltz,et al. Catalytic enantioselective construction of quaternary stereocenters: assembly of key building blocks for the synthesis of biologically active molecules. , 2015, Accounts of chemical research.
[7] K. Houk,et al. Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones , 2015, Chemical science.
[8] R. Gainetdinov,et al. Further Insights Into the Pharmacology of the Human Trace Amine‐Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach , 2014, Chemical biology & drug design.
[9] A. Minnaard,et al. Enantioselective palladium catalyzed conjugate additions of ortho-substituted arylboronic acids to β,β-disubstituted cyclic enones: total synthesis of herbertenediol, enokipodin A and enokipodin B. , 2014, Organic & biomolecular chemistry.
[10] Susanta Banerjee,et al. Effect of introduction of cardo cyclohexylidene moiety on gas transport properties of fluorinated poly(arylene ether)s , 2014 .
[11] Chun-Young Lee,et al. Protodeboronation of ortho- and para-phenol boronic acids and application to ortho and meta functionalization of phenols using boronic acids as blocking and directing groups. , 2013, The Journal of organic chemistry.
[12] K. Houk,et al. Mechanism and enantioselectivity in palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones: insights from computation and experiment. , 2013, Journal of the American Chemical Society.
[13] A. Hoveyda,et al. Enantioselective synthesis of quaternary carbon stereogenic centers through copper-catalyzed conjugate additions of aryl- and alkylaluminum reagents to acyclic trisubstituted enones. , 2013, Angewandte Chemie.
[14] C. Butts,et al. Diastereodivergent synthesis of trisubstituted alkenes through protodeboronation of allylic boronic esters: application to the synthesis of the Californian red scale beetle pheromone. , 2012, Angewandte Chemie.
[15] M. Lutz,et al. Palladium-Catalyzed Asymmetric Quaternary Stereocenter Formation , 2012, Synfacts.
[16] B. Stoltz,et al. Palladium-catalyzed asymmetric conjugate addition of arylboronic acids to five-, six-, and seven-membered β-substituted cyclic enones: enantioselective construction of all-carbon quaternary stereocenters. , 2011, Journal of the American Chemical Society.
[17] V. Aggarwal,et al. Protodeboronation of tertiary boronic esters: asymmetric synthesis of tertiary alkyl stereogenic centers. , 2010, Journal of the American Chemical Society.
[18] A. Alexakis,et al. Metal-catalyzed asymmetric conjugate addition reaction: formation of quaternary stereocenters. , 2010, Chemical communications.
[19] A. Alexakis,et al. Formation of quaternary chiral centers by N-heterocyclic carbene-Cu-catalyzed asymmetric conjugate addition reactions with Grignard reagents on trisubstituted cyclic enones. , 2010, Chemistry.
[20] S. Snyder,et al. Total syntheses of dalesconol A and B. , 2010, Angewandte Chemie.
[21] R. Shintani,et al. Chiral tetrafluorobenzobarrelenes as effective ligands for rhodium-catalyzed asymmetric 1,4-addition of arylboroxines to beta,beta-disubstituted alpha,beta-unsaturated ketones. , 2010, Angewandte Chemie.
[22] M. Burke,et al. General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates. , 2010, Organic letters.
[23] F. Glorius,et al. Olefin-oxazolines (OlefOx): highly modular, easily tunable ligands for asymmetric catalysis. , 2010, Angewandte Chemie.
[24] R. Shintani,et al. Sodium tetraarylborates as effective nucleophiles in rhodium/diene-catalyzed 1,4-addition to beta,beta-disubstituted alpha,beta-unsaturated ketones: catalytic asymmetric construction of quaternary carbon stereocenters. , 2009, Journal of the American Chemical Society.
[25] M. Burke,et al. A general solution for unstable boronic acids: slow-release cross-coupling from air-stable MIDA boronates. , 2009, Journal of the American Chemical Society.
[26] Michal M. Achmatowicz,et al. Practical synthesis of a p38 MAP kinase inhibitor. , 2009, The Journal of organic chemistry.
[27] A. Alexakis,et al. Copper-catalyzed asymmetric conjugate addition of aryl aluminum reagents to trisubstituted enones: construction of aryl-substituted quaternary centers. , 2008, Angewandte Chemie.
[28] A. Hoveyda,et al. Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones. , 2008, Angewandte Chemie.
[29] R. Harvey,et al. Efficient syntheses of C(8)-aryl adducts of adenine and guanine formed by reaction of radical cation metabolites of carcinogenic polycyclic aromatic hydrocarbons with DNA. , 2007, The Journal of organic chemistry.
[30] A. Hoveyda,et al. All-carbon quaternary stereogenic centers by enantioselective cu-catalyzed conjugate additions promoted by a chiral N-heterocyclic carbene. , 2007, Angewandte Chemie.
[31] A. Alexakis,et al. Copper-catalyzed asymmetric conjugate addition of Grignard reagents to trisubstituted enones. Construction of all-carbon quaternary chiral centers. , 2006, Journal of the American Chemical Society.
[32] A. Hird,et al. A practical method for enantioselective synthesis of all-carbon quaternary stereogenic centers through NHC-Cu-catalyzed conjugate additions of alkyl- and arylzinc reagents to beta-substituted cyclic enones. , 2006, Journal of the American Chemical Society.
[33] E. Nesterov,et al. An experimental and theoretical study of the type C enone rearrangement: mechanistic and exploratory organic photochemistry. , 2003, Journal of the American Chemical Society.
[34] K. Tsubaki,et al. Asymmetric synthesis and determination of the absolute configuration of FK584, an agent for the treatment of overactive detrusor. , 2000, Chemical & pharmaceutical bulletin.
[35] D. L. Larson,et al. Synthesis of 7-arylmorphinans. Probing the "address" requirements for selectivity at opioid delta receptors. , 1998, Journal of medicinal chemistry.
[36] M. Beckett,et al. Protodeboronation of arylboronic acids and triarylboroxines in Bu20/THF , 1993 .
[37] H. Kuivila,et al. Electrophilic Displacement Reactions. X. General Acid Catalysis in the Protodeboronation of Areneboronic Acids1-3 , 1961 .
[38] H. Kuivila,et al. Electrophilic Displacement Reactions. XII. Substituent Effects in the Protodeboronation of Areneboronic Acids1-3 , 1961 .
[39] F. Challenger,et al. CCLXXX.—Studies of the boron–carbon linkage. Part I. The oxidation and nitration of phenylboric acid , 1930 .