Esophageal vasculitis in granulomatosis with polyangiitis.

Granulomatosis with polyangiitis (GPA; formerly Wegener’s granulomatosis) affects the gastrointestinal tract infrequently as compared to other small or medium vessel vasculitis. Case reports of lower gastrointestinal (GI) involvement in GPA are numerous but esophageal vasculitis due to GPA is extremely rare. Only six cases of esophageal involvement in GPA have been reported in the literature thus far. We present the diagnostic and treatment challenges in a case of esophageal ulceration due to GPA and review the relevant literature.