Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations

[1]  P. Sullivan,et al.  Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample. , 2008, Alcoholism, clinical and experimental research.

[2]  H. Shin,et al.  Major genetic components underlying alcoholism in Korean population. , 2008, Human molecular genetics.

[3]  S. Yin,et al.  Pharmacokinetic and pharmacodynamic basis for partial protection against alcoholism in Asians, heterozygous for the variant ALDH2*2 gene allele , 2007, Pharmacogenetics and genomics.

[4]  K. Kidd,et al.  Geographically separate increases in the frequency of the derived ADH1B*47His allele in eastern and western Asia. , 2007, American journal of human genetics.

[5]  J. Stamler,et al.  Structural and Functional Consequences of Coenzyme Binding to the Inactive Asian Variant of Mitochondrial Aldehyde Dehydrogenase , 2007, Journal of Biological Chemistry.

[6]  Eriksson Cj Measurement of acetaldehyde: what levels occur naturally and in response to alcohol? , 2007 .

[7]  S. Yin,et al.  Acetaldehyde, polymorphisms and the cardiovascular system. , 2007, Novartis Foundation symposium.

[8]  V. Vasiliou,et al.  Removal of acetaldehyde from the body. , 2007, Novartis Foundation symposium.

[9]  C. Eriksson Measurement of acetaldehyde: what levels occur naturally and in response to alcohol? , 2007, Novartis Foundation symposium.

[10]  T. Foroud,et al.  REVIEW: The genetics of alcoholism: identifying specific genes through family studies , 2006, Addiction biology.

[11]  G. Chau,et al.  Functional assessment of human alcohol dehydrogenase family in ethanol metabolism: significance of first-pass metabolism. , 2006, Alcoholism, clinical and experimental research.

[12]  N. Schork,et al.  Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. , 2006, American journal of human genetics.

[13]  L. Bierut,et al.  Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. , 2006, Human molecular genetics.

[14]  Mauro Santos,et al.  Do alcohol‐metabolizing enzyme gene polymorphisms increase the risk of alcoholism and alcoholic liver disease? , 2006, Hepatology.

[15]  James E. Bray,et al.  Enzymology and Molecular Biology of Carbonyl Metabolism , 2005 .

[16]  B. Kee,et al.  Scanning of genetic effects of alcohol metabolism gene (ADH1B and ADH1C) polymorphisms on the risk of alcoholism , 2005, Human mutation.

[17]  V. Preedy,et al.  Comprehensive handbook of alcohol related pathology. , 2005 .

[18]  J. Höög,et al.  Functionality of allelic variations in human alcohol dehydrogenase gene family: assessment of a functional window for protection against alcoholism. , 2004, Pharmacogenetics.

[19]  D. Crabb,et al.  Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology , 2004, Proceedings of the Nutrition Society.

[20]  S. Yin,et al.  33 – Overview of ALDH Polymorphism: Relation to Cardiovascular Effects of Alcohol , 2004 .

[21]  T. Li,et al.  Alcohol dehydrogenase polymorphisms influence alcohol-elimination rates in a male Jewish population. , 2004, Alcoholism, clinical and experimental research.

[22]  C. Ehlers,et al.  Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission Indians. , 2003, The American journal of psychiatry.

[23]  S. Yin,et al.  Alcohol sensitivity in Taiwanese men with different alcohol and aldehyde dehydrogenase genotypes. , 2002, Journal of the Formosan Medical Association = Taiwan yi zhi.

[24]  D. Agarwal,et al.  Functional Polymorphism of Alcohol and Aldehyde Dehydrogenases: Alcohol Metabolism, Alcoholism, and Alcohol- Induced Organ Damage , 2001 .

[25]  S. Yin Functional Polymorphism of Alcohol and Aldehyde Dehydrogenases , 2001 .

[26]  B. Gibbons,et al.  Three‐dimensional structures of the three human class I alcohol dehydrogenases , 2001, Protein science : a publication of the Protein Society.

[27]  Ting-kai Li,et al.  Genetic and environmental influences on alcohol metabolism in humans. , 2001, Alcoholism, clinical and experimental research.

[28]  H. Weiner,et al.  Basis for half-of-the-site reactivity and the dominance of the K487 oriental subunit over the E487 subunit in heterotetrameric human liver mitochondrial aldehyde dehydrogenase. , 2000, Biochemistry.

[29]  T. Li,et al.  Alcohol metabolism and cardiovascular response in an alcoholic patient homozygous for the ALDH2*2 variant gene allele. , 1999, Alcoholism, clinical and experimental research.

[30]  V. Vasiliou,et al.  Mouse cytosolic class 3 aldehyde dehydrogenase (Aldh3a1): gene structure and regulation of constitutive and dioxin-inducible expression. , 1999, Pharmacogenetics.

[31]  C. C. Chen,et al.  Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. , 1999, American journal of human genetics.

[32]  A. Bairoch,et al.  Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping. , 1999, Pharmacogenetics.

[33]  Ting-kai Li,et al.  Involvement of acetaldehyde for full protection against alcoholism by homozygosity of the variant allele of mitochondrial aldehyde dehydrogenase gene in Asians. , 1999, Pharmacogenetics.

[34]  H. Jörnvall,et al.  Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family. , 1999, Biochemical pharmacology.

[35]  S. Yin,et al.  Human stomach alcohol and aldehyde dehydrogenases: comparison of expression pattern and activities in alimentary tract. , 1997, Gastroenterology.

[36]  S. Yin,et al.  Substrate binding pocket structure of human aldehyde dehydrogenases. A substrate specificity approach. , 1995, Advances in experimental medicine and biology.

[37]  Y. Ueno,et al.  Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism. , 1994, Alcohol and alcoholism.

[38]  S. Higuchi,et al.  Aldehyde dehydrogenase genotypes In Japanese alcoholics , 1994, The Lancet.

[39]  D. Agarwal,et al.  Pharmacogenetics of alcohol metabolism and alcoholism. , 1992, Pharmacogenetics.

[40]  K. Lindros,et al.  Blood acetaldehyde concentration gradient between hepatic and antecubital venous blood in ethanol‐intoxicated alcoholics and controls* , 1984, European journal of clinical investigation.